2021 ICD-10-CM Diagnosis Code E89.3

Postprocedural hypopituitarism

    2016 2017 2018 2019 2020 2021 Billable/Specific Code
  • E89.3 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2021 edition of ICD-10-CM E89.3 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of E89.3 - other international versions of ICD-10 E89.3 may differ.
Applicable To
  • Postirradiation hypopituitarism
The following code(s) above E89.3 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E89.3:
  • E00-E89
    2021 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
  • E89
    ICD-10-CM Diagnosis Code E89

    Postprocedural endocrine and metabolic complications and disorders, not elsewhere classified

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 2 Excludes
    • intraoperative complications of endocrine system organ or structure (E36.0-, E36.1-, E36.8)
    Postprocedural endocrine and metabolic complications and disorders, not elsewhere classified
Approximate Synonyms
  • Hypopituitarism due to pituitary tumor surgery
  • Hypopituitarism due to radiotherapy
  • Iatrogenic pituitary disorder
  • Pituitary disorder, iatrogenic
  • Radiotherapy-induced hypopituitarism
ICD-10-CM E89.3 is grouped within Diagnostic Related Group(s) (MS-DRG v38.0):
  • 643 Endocrine disorders with mcc
  • 644 Endocrine disorders with cc
  • 645 Endocrine disorders without cc/mcc

Convert E89.3 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
Code annotations containing back-references to E89.3:
  • Type 1 Excludes: E23
    ICD-10-CM Diagnosis Code E23

    Hypofunction and other disorders of the pituitary gland

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Includes
    • the listed conditions whether the disorder is in the pituitary or the hypothalamus
    Type 1 Excludes
    • postprocedural hypopituitarism (E89.3)

Diagnosis Index entries containing back-references to E89.3:
  • Absence (of) (organ or part) (complete or partial)
    • pituitary gland (congenital) Q89.2
      ICD-10-CM Diagnosis Code Q89.2

      Congenital malformations of other endocrine glands

        2016 2017 2018 2019 2020 2021 Billable/Specific Code POA Exempt
      Applicable To
      • Congenital malformation of parathyroid or thyroid gland
      • Persistent thyroglossal duct
      • Thyroglossal cyst
      Type 1 Excludes
      • congenital goiter (E03.0)
      • congenital hypothyroidism (E03.1)
      • acquired E89.3
  • Complication(s) (from) (of)
    • endocrine E34.9
      ICD-10-CM Diagnosis Code E34.9

      Endocrine disorder, unspecified

        2016 2017 2018 2019 2020 2021 Billable/Specific Code
      Applicable To
      • Endocrine disturbance NOS
      • Hormone disturbance NOS
    • surgical procedure (on) T81.9
      ICD-10-CM Diagnosis Code T81.9

      Unspecified complication of procedure

        2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
      • hypopituitarism E89.3 (posthypophysectomy)
  • Disorder (of) - see also Disease
    • pituitary gland E23.7
      ICD-10-CM Diagnosis Code E23.7

      Disorder of pituitary gland, unspecified

        2016 2017 2018 2019 2020 2021 Billable/Specific Code
      • iatrogenic E89.3 (postprocedural)
  • Hypopituitarism (juvenile) E23.0
    ICD-10-CM Diagnosis Code E23.0

    Hypopituitarism

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Fertile eunuch syndrome
    • Hypogonadotropic hypogonadism
    • Idiopathic growth hormone deficiency
    • Isolated deficiency of gonadotropin
    • Isolated deficiency of growth hormone
    • Isolated deficiency of pituitary hormone
    • Kallmann's syndrome
    • Lorain-Levi short stature
    • Necrosis of pituitary gland (postpartum)
    • Panhypopituitarism
    • Pituitary cachexia
    • Pituitary insufficiency NOS
    • Pituitary short stature
    • Sheehan's syndrome
    • Simmonds' disease
    • due to
      • hypophysectomy E89.3
      • radiotherapy E89.3
    • postirradiation E89.3
    • postprocedural E89.3

ICD-10-CM Codes Adjacent To E89.3
E88.42 MERRF syndrome
E88.49 Other mitochondrial metabolism disorders
E88.8 Other specified metabolic disorders
E88.81 Metabolic syndrome
E88.89 Other specified metabolic disorders
E88.9 Metabolic disorder, unspecified
E89 Postprocedural endocrine and metabolic complications and disorders, not elsewhere classified
E89.0 Postprocedural hypothyroidism
E89.1 Postprocedural hypoinsulinemia
E89.2 Postprocedural hypoparathyroidism
E89.3 Postprocedural hypopituitarism
E89.4 Postprocedural ovarian failure
E89.40 Asymptomatic postprocedural ovarian failure
E89.41 Symptomatic postprocedural ovarian failure
E89.5 Postprocedural testicular hypofunction
E89.6 Postprocedural adrenocortical (-medullary) hypofunction
E89.8 Other postprocedural endocrine and metabolic complications and disorders
E89.81 Postprocedural hemorrhage of an endocrine system organ or structure following a procedure
E89.810 Postprocedural hemorrhage of an endocrine system organ or structure following an endocrine system procedure
E89.811 Postprocedural hemorrhage of an endocrine system organ or structure following other procedure
E89.82 Postprocedural hematoma and seroma of an endocrine system organ or structure

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.