2021 ICD-10-CM Diagnosis Code G12.0

Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]

    2016 2017 2018 2019 2020 2021 Billable/Specific Code
  • G12.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2021 edition of ICD-10-CM G12.0 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of G12.0 - other international versions of ICD-10 G12.0 may differ.
The following code(s) above G12.0 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to G12.0:
  • G00-G99
    2021 ICD-10-CM Range G00-G99

    Diseases of the nervous system

    Type 2 Excludes
    • certain conditions originating in the perinatal period (P04-P96)
    • certain infectious and parasitic diseases (A00-B99)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the nervous system
Approximate Synonyms
  • Werdnig hoffmann disease
Clinical Information
  • The most severe form of spinal muscular atrophy. It is manifested in the first year of life with muscle weakness, poor muscle tone, and lack of motor development. The motor neuron death affects the major organ systems, particularly the respiratory system. Most patients die before the age of two secondary to pneumonia.
ICD-10-CM G12.0 is grouped within Diagnostic Related Group(s) (MS-DRG v38.0):
  • 056 Degenerative nervous system disorders with mcc
  • 057 Degenerative nervous system disorders without mcc

Convert G12.0 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change

Diagnosis Index entries containing back-references to G12.0:
  • Atrophy, atrophic (of)
    • muscle, muscular (diffuse) (general) (idiopathic) (primary) M62.50
      ICD-10-CM Diagnosis Code M62.50

      Muscle wasting and atrophy, not elsewhere classified, unspecified site

        2016 2017 2018 2019 2020 2021 Billable/Specific Code
      • progressive (bulbar) G12.21
        ICD-10-CM Diagnosis Code G12.21

        Amyotrophic lateral sclerosis

          2016 2017 2018 2019 2020 2021 Billable/Specific Code Adult Dx (15-124 years)
        • spinal G12.25
          ICD-10-CM Diagnosis Code G12.25

          Progressive spinal muscle atrophy

            2018 - New Code 2019 2020 2021 Billable/Specific Code
          • infantile G12.0
        • infantile G12.0 (spinal)
      • spinal G12.9
        ICD-10-CM Diagnosis Code G12.9

        Spinal muscular atrophy, unspecified

          2016 2017 2018 2019 2020 2021 Billable/Specific Code
        • infantile, type I G12.0 (Werdnig-Hoffmann)
      • infantile spinal G12.0
    • Werdnig-Hoffmann G12.0
  • Disease, diseased - see also Syndrome
    • Werdnig-Hoffmann G12.0
  • Syndrome - see also Disease
    • Hoffmann-Werdnig G12.0
    • Werdnig-Hoffman G12.0
  • Werdnig-Hoffmann syndrome G12.0 (muscular atrophy)

ICD-10-CM Codes Adjacent To G12.0
G11.1 Early-onset cerebellar ataxia
G11.10 …… unspecified
G11.11 Friedreich ataxia
G11.19 Other early-onset cerebellar ataxia
G11.2 Late-onset cerebellar ataxia
G11.3 Cerebellar ataxia with defective DNA repair
G11.4 Hereditary spastic paraplegia
G11.8 Other hereditary ataxias
G11.9 Hereditary ataxia, unspecified
G12 Spinal muscular atrophy and related syndromes
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
G12.1 Other inherited spinal muscular atrophy
G12.2 Motor neuron disease
G12.20 …… unspecified
G12.21 Amyotrophic lateral sclerosis
G12.22 Progressive bulbar palsy
G12.23 Primary lateral sclerosis
G12.24 Familial motor neuron disease
G12.25 Progressive spinal muscle atrophy
G12.29 Other motor neuron disease
G12.8 Other spinal muscular atrophies and related syndromes

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.