2023 ICD-10-CM Diagnosis Code G37.1

Central demyelination of corpus callosum

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • G37.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2023 edition of ICD-10-CM G37.1 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of G37.1 - other international versions of ICD-10 G37.1 may differ.
The following code(s) above G37.1 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to G37.1:
  • G00-G99
    2023 ICD-10-CM Range G00-G99

    Diseases of the nervous system

    Type 2 Excludes
    • certain conditions originating in the perinatal period (P04-P96)
    • certain infectious and parasitic diseases (A00-B99)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the nervous system
Approximate Synonyms
  • Central demyelination, corpus callosum
  • Marchiafava-bignami disease
Clinical Information
  • A neurodegenerative condition that is characterized by demyelination or necrosis of the corpus callosum. Symptoms include depression; paranoia; dementia; seizures; and ataxia which can progress to coma and death in a few months. Marchiafava-bignami syndrome is seen often in alcoholics but has been found in non-alcoholics as well.
  • Progressive degeneration of the corpus callosum characterized by progressive intellectual deterioration, emotional disturbances, confusion, hallucinations, tremor, rigidity, and convulsions; very rare disorder affecting chiefly middle-aged male alcoholics and patients with nutritional deficiency states.
ICD-10-CM G37.1 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 058 Multiple sclerosis and cerebellar ataxia with mcc
  • 059 Multiple sclerosis and cerebellar ataxia with cc
  • 060 Multiple sclerosis and cerebellar ataxia without cc/mcc

Convert G37.1 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change

Diagnosis Index entries containing back-references to G37.1:
  • Demyelination, demyelinization
    • corpus callosum G37.1 (central)
  • Encephalopathy (acute) G93.40
    ICD-10-CM Diagnosis Code G93.40

    Encephalopathy, unspecified

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    • demyelinating callosal G37.1
  • Marchiafava G37.1 (-Bignami)

ICD-10-CM Codes Adjacent To G37.1
G32.81 Cerebellar ataxia in diseases classified elsewhere
G32.89 Other specified degenerative disorders of nervous system in diseases classified elsewhere
G35 Multiple sclerosis
G36 Other acute disseminated demyelination
G36.0 Neuromyelitis optica [Devic]
G36.1 Acute and subacute hemorrhagic leukoencephalitis [Hurst]
G36.8 Other specified acute disseminated demyelination
G36.9 Acute disseminated demyelination, unspecified
G37 Other demyelinating diseases of central nervous system
G37.0 Diffuse sclerosis of central nervous system
G37.1 Central demyelination of corpus callosum
G37.2 Central pontine myelinolysis
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
G37.4 Subacute necrotizing myelitis of central nervous system
G37.5 Concentric sclerosis [Balo] of central nervous system
G37.8 Other specified demyelinating diseases of central nervous system
G37.9 Demyelinating disease of central nervous system, unspecified
G40 Epilepsy and recurrent seizures
G40.0 Localization-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localized onset
G40.00 Localization-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localized onset, not intractable
G40.001 …… with status epilepticus

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.