2019 ICD-10-CM Diagnosis Code G72.3

Periodic paralysis

    2016 2017 2018 2019 Billable/Specific Code
  • G72.3 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2019 edition of ICD-10-CM G72.3 became effective on October 1, 2018.
  • This is the American ICD-10-CM version of G72.3 - other international versions of ICD-10 G72.3 may differ.
Applicable To
  • Familial periodic paralysis
  • Hyperkalemic periodic paralysis (familial)
  • Hypokalemic periodic paralysis (familial)
  • Myotonic periodic paralysis (familial)
  • Normokalemic paralysis (familial)
  • Potassium sensitive periodic paralysis
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as G72.3. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • paramyotonia congenita (of von Eulenburg) (
    ICD-10-CM Diagnosis Code G71.19

    Other specified myotonic disorders

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Myotonia fluctuans
    • Myotonia permanens
    • Neuromyotonia [Isaacs]
    • Paramyotonia congenita (of von Eulenburg)
    • Pseudomyotonia
    • Symptomatic myotonia
    G71.19
    )
The following code(s) above G72.3 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to G72.3:
  • G00-G99
    2019 ICD-10-CM Range G00-G99

    Diseases of the nervous system

    Type 2 Excludes
    • certain conditions originating in the perinatal period (P04-P96)
    • certain infectious and parasitic diseases (A00-B99)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the nervous system
  • G72
    ICD-10-CM Diagnosis Code G72

    Other and unspecified myopathies

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • arthrogryposis multiplex congenita (Q74.3)
    • dermatopolymyositis (M33.-)
    • ischemic infarction of muscle (M62.2-)
    • myositis (M60.-)
    • polymyositis (M33.2.-)
    Other and unspecified myopathies
Approximate Synonyms
  • Familial periodic paralysis
  • Periodic paralysis, familial
Clinical Information
  • A group of genetic neurological disorders caused by mutations in genes involved in the sodium and calcium channels in nerve cells. It is characterized by episodes of muscle paralysis in which the affected muscles become flaccid and the deep tendon reflexes disappear. Between the episodes the affected muscles usually work normally.
  • A heterogenous group of inherited disorders characterized by recurring attacks of rapidly progressive flaccid paralysis or myotonia. These conditions have in common a mutation of the gene encoding the alpha subunit of the sodium channel in skeletal muscle. They are frequently associated with fluctuations in serum potassium levels. Periodic paralysis may also occur as a non-familial process secondary to thyrotoxicosis and other conditions. (from Adams et al., Principles of Neurology, 6th ed, p1481)
  • An autosomal dominant familial disorder characterized by recurrent episodes of skeletal muscle weakness associated with falls in serum potassium levels. The condition usually presents in the first or second decade of life with attacks of trunk and leg paresis during sleep or shortly after awakening. Symptoms may persist for hours to days and generally are precipitated by exercise or a meal high in carbohydrates. (Adams et al., Principles of Neurology, 6th ed, p1483)
  • An autosomal dominant familial disorder which presents in infancy or childhood and is characterized by episodes of weakness associated with hyperkalemia. During attacks, muscles of the lower extremities are initially affected, followed by the lower trunk and arms. Episodes last from 15-60 minutes and typically occur after a period of rest following exercise. A defect in skeletal muscle sodium channels has been identified as the cause of this condition. Normokalemic periodic paralysis is a closely related disorder marked by a lack of alterations in potassium levels during attacks of weakness. (Adams et al., Principles of Neurology, 6th ed, p1481)
  • An autosomal dominant inherited or genetic disorder characterized by irregular episodes of muscle weakness or paralysis which are always accompanied by low levels of potassium in the blood.
  • Heterogenous group of inherited disorders characterized by recurring attacks of rapidly progressive flaccid paralysis or myotonia; these conditions have in common a mutation of the gene encoding the alpha subunit of the sodium channel in skeletal muscle; frequently associated with fluctuations in serum potassium levels; periodic paralysis may also occur as a non-familial process secondary to thyrotoxicosis and other conditions.
ICD-10-CM G72.3 is grouped within Diagnostic Related Group(s) (MS-DRG v36.0):
  • 091 Other disorders of nervous system with mcc
  • 092 Other disorders of nervous system with cc
  • 093 Other disorders of nervous system without cc/mcc

Convert G72.3 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
Code annotations containing back-references to G72.3:
  • Type 1 Excludes: E87
    ICD-10-CM Diagnosis Code E87

    Other disorders of fluid, electrolyte and acid-base balance

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • diabetes insipidus (E23.2)
    • electrolyte imbalance associated with hyperemesis gravidarum (O21.1)
    • electrolyte imbalance following ectopic or molar pregnancy (O08.5)
    • familial periodic paralysis (G72.3)

Diagnosis Index entries containing back-references to G72.3:
  • Adynamia G72.3 (episodica) (hereditary) (periodic)
  • Cavare's disease G72.3 (familial periodic paralysis)
  • Disease, diseased - see also Syndrome
    • Cavare's G72.3 (familial periodic paralysis)
    • familial periodic paralysis G72.3
    • Gamstorp's G72.3 (adynamia episodica hereditaria)
  • Gamstorp's disease G72.3 (adynamia episodica hereditaria)
  • Paralysis, paralytic (complete) (incomplete) G83.9
    ICD-10-CM Diagnosis Code G83.9

    Paralytic syndrome, unspecified

      2016 2017 2018 2019 Billable/Specific Code
    • familial (recurrent) (periodic) G72.3
    • hyperkalemic periodic G72.3 (familial)
    • hypokalemic periodic G72.3
    • normokalemic periodic G72.3
    • periodic G72.3 (familial) (hyperkalemic) (hypokalemic) (myotonic) (normokalemic) (potassium sensitive) (secondary)

ICD-10-CM Codes Adjacent To G72.3
G71.14 Drug induced myotonia
G71.19 Other specified myotonic disorders
G71.2 Congenital myopathies
G71.3 Mitochondrial myopathy, not elsewhere classified
G71.8 Other primary disorders of muscles
G71.9 Primary disorder of muscle, unspecified
G72 Other and unspecified myopathies
G72.0 Drug-induced myopathy
G72.1 Alcoholic myopathy
G72.2 Myopathy due to other toxic agents
G72.3 Periodic paralysis
G72.4 Inflammatory and immune myopathies, not elsewhere classified
G72.41 Inclusion body myositis [IBM]
G72.49 Other inflammatory and immune myopathies, not elsewhere classified
G72.8 Other specified myopathies
G72.81 Critical illness myopathy
G72.89 Other specified myopathies
G72.9 Myopathy, unspecified
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
G73.1 Lambert-Eaton syndrome in neoplastic disease
G73.3 Myasthenic syndromes in other diseases classified elsewhere

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.