2022 ICD-10-CM Diagnosis Code G92.0

Immune effector cell-associated neurotoxicity syndrome

    2022 - New Code Non-Billable/Non-Specific Code
  • G92.0 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • ICD-10-CM G92.0 is a new 2022 ICD-10-CM code that became effective on October 1, 2021.
  • This is the American ICD-10-CM version of G92.0 - other international versions of ICD-10 G92.0 may differ.
Code First
Code First Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • underlying cause such as:
  • complications of immune effector cellular therapy (
    ICD-10-CM Diagnosis Code T80.82

    Complication of immune effector cellular therapy

      2022 - New Code Non-Billable/Non-Specific Code
    Applicable To
    • Complication of chimeric antigen receptor (CAR-T) cell therapy
    • Complication of IEC therapy
    Type 2 Excludes
    • complication of bone marrow transplant (T86.0)
    • complication of stem cell transplant (T86.5)
    Use Additional
    • code to identify the specific complication, such as:
    • cytokine release syndrome (D89.83-)
    • immune effector cell-associated neurotoxicity syndrome (G92.0-)
    T80.82
    )
Code Also
Code Also Help
A code also note instructs that 2 codes may be required to fully describe a condition but the sequencing of the two codes is discretionary, depending on the severity of the conditions and the reason for the encounter.
  • associated signs and symptoms, such as seizures and cerebral edema
The following code(s) above G92.0 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to G92.0:
  • G00-G99
    2022 ICD-10-CM Range G00-G99

    Diseases of the nervous system

    Type 2 Excludes
    • certain conditions originating in the perinatal period (P04-P96)
    • certain infectious and parasitic diseases (A00-B99)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the nervous system
Code History
  • 2022 (effective 10/1/2021): New code
Code annotations containing back-references to G92.0:
  • Use Additional: T80.82
    ICD-10-CM Diagnosis Code T80.82

    Complication of immune effector cellular therapy

      2022 - New Code Non-Billable/Non-Specific Code
    Applicable To
    • Complication of chimeric antigen receptor (CAR-T) cell therapy
    • Complication of IEC therapy
    Type 2 Excludes
    • complication of bone marrow transplant (T86.0)
    • complication of stem cell transplant (T86.5)
    Use Additional
    • code to identify the specific complication, such as:
    • cytokine release syndrome (D89.83-)
    • immune effector cell-associated neurotoxicity syndrome (G92.0-)
ICD-10-CM Codes Adjacent To G92.0
G90.9 Disorder of the autonomic nervous system, unspecified
G91 Hydrocephalus
G91.0 Communicating hydrocephalus
G91.1 Obstructive hydrocephalus
G91.2 (Idiopathic) normal pressure hydrocephalus
G91.3 Post-traumatic hydrocephalus, unspecified
G91.4 Hydrocephalus in diseases classified elsewhere
G91.8 Other hydrocephalus
G91.9 Hydrocephalus, unspecified
G92 Toxic encephalopathy
G92.0 Immune effector cell-associated neurotoxicity syndrome
G92.00 …… grade unspecified
G92.01 …… grade 1
G92.02 …… grade 2
G92.03 …… grade 3
G92.04 …… grade 4
G92.05 …… grade 5
G92.8 Other toxic encephalopathy
G92.9 Unspecified toxic encephalopathy
G93 Other disorders of brain
G93.0 Cerebral cysts

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.