2019 ICD-10-CM Diagnosis Code G93.7

Reye's syndrome

    2016 2017 2018 2019 Billable/Specific Code Pediatric Dx (0-17 years)
  • G93.7 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2019 edition of ICD-10-CM G93.7 became effective on October 1, 2018.
  • This is the American ICD-10-CM version of G93.7 - other international versions of ICD-10 G93.7 may differ.
ICD-10-CM Coding Rules
  • G93.7 is applicable to pediatric patients aged 0 - 17 years inclusive.
Use Additional
Use Additional Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • code for adverse effect due to salicylates, if applicable (
    ICD-10-CM Diagnosis Code T39.0

    Poisoning by, adverse effect of and underdosing of salicylates

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    T39.0-
    , with sixth character 5)
Code First
Code First Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • poisoning due to salicylates, if applicable (
    ICD-10-CM Diagnosis Code T39.0

    Poisoning by, adverse effect of and underdosing of salicylates

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    T39.0-
    , with sixth character 1-4)
The following code(s) above G93.7 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to G93.7:
  • G00-G99
    2019 ICD-10-CM Range G00-G99

    Diseases of the nervous system

    Type 2 Excludes
    • certain conditions originating in the perinatal period (P04-P96)
    • certain infectious and parasitic diseases (A00-B99)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the nervous system
Approximate Synonyms
  • Reyes syndrome
Clinical Information
  • A form of encephalopathy with fatty infiltration of the liver, characterized by brain edema and vomiting that may rapidly progress to seizures; coma; and death. It is caused by a generalized loss of mitochondrial function leading to disturbances in fatty acid and carnitine metabolism.
  • A rare disease that damages the brain and liver and causes death if not treated. It occurs most often in children younger than 15 years who have had a fever-causing virus, such as chickenpox or flu. Taking aspirin during a viral illness may increase the risk of reye syndrome.
  • An acute and potentially fatal metabolic disorder characterized by cerebral edema, fatty liver and hypoglycemia. It occurs primarily in children and has been associated with the use of aspirin for the treatment of viral infections. However, it can also occur in the absence of aspirin use.
  • Rare, acute, sometimes fatal disease of childhood, most often occurring as a sequel of varicella or a viral upper respiratory infection of childhood; marked by recurrent vomiting and elevated serum transaminase levels with distinctive changes in the liver and other viscera; an encephalopathic phase with acute brain swelling disturbances of consciousness and seizures may follow.
  • Reye syndrome is a rare illness that can affect the blood, liver and brain of someone who recently had a viral infection. It always follows another illness. Although it mostly affects children and teens, anyone can get it. It can develop quickly and without warning. It is most common during flu season. Symptoms include
    • nausea and vomiting
    • listlessness
    • personality change - such as irritability, combativeness or confusion
    • delirium
    • convulsions
    • loss of consciousness
    if these symptoms occur soon after a viral illness, seek medical attention immediately. Reye syndrome can lead to a coma and brain death, so quick diagnosis and treatment are critical. Treatment focuses on preventing brain damage. There is no cure.the cause of reye syndrome is unknown. However, studies have shown that taking aspirin increases the risk of getting it. Because of that, health care professionals now recommend other pain relievers for young patients.
ICD-10-CM G93.7 is grouped within Diagnostic Related Group(s) (MS-DRG v36.0):
  • 091 Other disorders of nervous system with mcc
  • 092 Other disorders of nervous system with cc
  • 093 Other disorders of nervous system without cc/mcc

Convert G93.7 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
Code annotations containing back-references to G93.7:
  • Type 1 Excludes: E88.4
    , G71.3
    ICD-10-CM Diagnosis Code E88.4

    Mitochondrial metabolism disorders

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • disorders of pyruvate metabolism (E74.4)
    • Kearns-Sayre syndrome (H49.81)
    • Leber's disease (H47.22)
    • Leigh's encephalopathy (G31.82)
    • Mitochondrial myopathy, NEC (G71.3)
    • Reye's syndrome (G93.7)
    ICD-10-CM Diagnosis Code G71.3

    Mitochondrial myopathy, not elsewhere classified

      2016 2017 2018 2019 Billable/Specific Code
    Type 1 Excludes
    • Kearns-Sayre syndrome (H49.81)
    • Leber's disease (H47.21)
    • Leigh's encephalopathy (G31.82)
    • mitochondrial metabolism disorders (E88.4.-)
    • Reye's syndrome (G93.7)
  • Type 2 Excludes: G31
    ICD-10-CM Diagnosis Code G31

    Other degenerative diseases of nervous system, not elsewhere classified

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Type 2 Excludes
    Use Additional
    • code to identify:
    • dementia with behavioral disturbance (F02.81)
    • dementia without behavioral disturbance (F02.80)

Diagnosis Index entries containing back-references to G93.7:
  • Reye's syndrome G93.7
  • Syndrome - see also Disease
    • Reye's G93.7

ICD-10-CM Codes Adjacent To G93.7
G93.0 Cerebral cysts
G93.1 Anoxic brain damage, not elsewhere classified
G93.2 Benign intracranial hypertension
G93.3 Postviral fatigue syndrome
G93.4 Other and unspecified encephalopathy
G93.40 Encephalopathy, unspecified
G93.41 Metabolic encephalopathy
G93.49 Other encephalopathy
G93.5 Compression of brain
G93.6 Cerebral edema
G93.7 Reye's syndrome
G93.8 Other specified disorders of brain
G93.81 Temporal sclerosis
G93.82 Brain death
G93.89 Other specified disorders of brain
G93.9 Disorder of brain, unspecified
G94 Other disorders of brain in diseases classified elsewhere
G95 Other and unspecified diseases of spinal cord
G95.0 Syringomyelia and syringobulbia
G95.1 Vascular myelopathies
G95.11 Acute infarction of spinal cord (embolic) (nonembolic)

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.