2020 ICD-10-CM Diagnosis Code I68.0

Cerebral amyloid angiopathy

    2016 2017 2018 2019 2020 Billable/Specific Code Manifestation Code
  • I68.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2020 edition of ICD-10-CM I68.0 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of I68.0 - other international versions of ICD-10 I68.0 may differ.
ICD-10-CM Coding Rules
  • I68.0 describes the manifestation of an underlying disease, not the disease itself.
Code First
Code First Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • underlying amyloidosis (
    ICD-10-CM Diagnosis Code E85
    • E85 Amyloidosis
      • E85.0 Non-neuropathic heredofamilial amyloidosis
      • E85.1 Neuropathic heredofamilial amyloidosis
      • E85.2 Heredofamilial amyloidosis, unspecified
      • E85.3 Secondary systemic amyloidosis
      • E85.4 Organ-limited amyloidosis
      • E85.8 Other amyloidosis
        • E85.81 Light chain (AL) amyloidosis
        • E85.82 Wild-type transthyretin-related (ATTR) amyloi...
        • E85.89 Other amyloidosis
      • E85.9 Amyloidosis, unspecified
    E85.-
    )
The following code(s) above I68.0 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to I68.0:
  • I00-I99
    2020 ICD-10-CM Range I00-I99

    Diseases of the circulatory system

    Type 2 Excludes
    • certain conditions originating in the perinatal period (P04-P96)
    • certain infectious and parasitic diseases (A00-B99)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    • systemic connective tissue disorders (M30-M36)
    • transient cerebral ischemic attacks and related syndromes (G45.-)
    Diseases of the circulatory system
  • I60-I69
    2020 ICD-10-CM Range I60-I69

    Cerebrovascular diseases

    Type 1 Excludes
    • traumatic intracranial hemorrhage (S06.-)
    Use Additional
    • code to identify presence of:
    • alcohol abuse and dependence (F10.-)
    • exposure to environmental tobacco smoke (Z77.22)
    • history of tobacco dependence (Z87.891)
    • hypertension (I10-I16)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)
    Cerebrovascular diseases
Clinical Information
  • A disorder characterized by the deposition of amyloid in the wall of the vessels in the brain.
  • A heterogeneous group of sporadic or familial disorders characterized by amyloid deposits in the walls of small and medium sized blood vessels of cerebral cortex and meninges. Clinical features include multiple, small lobar cerebral hemorrhage; cerebral ischemia (brain ischemia); and cerebral infarction. Cerebral amyloid angiopathy is unrelated to generalized amyloidosis. Amyloidogenic peptides in this condition are nearly always the same ones found in alzheimer disease. (from kumar: robbins and cotran: pathologic basis of disease, 7th ed., 2005)
ICD-10-CM I68.0 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0):
  • 070 Nonspecific cerebrovascular disorders with mcc
  • 071 Nonspecific cerebrovascular disorders with cc
  • 072 Nonspecific cerebrovascular disorders without cc/mcc

Convert I68.0 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
ICD-10-CM Codes Adjacent To I68.0
I67.83 Posterior reversible encephalopathy syndrome
I67.84 Cerebral vasospasm and vasoconstriction
I67.841 Reversible cerebrovascular vasoconstriction syndrome
I67.848 Other cerebrovascular vasospasm and vasoconstriction
I67.85 Hereditary cerebrovascular diseases
I67.850 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
I67.858 Other hereditary cerebrovascular disease
I67.89 Other cerebrovascular disease
I67.9 Cerebrovascular disease, unspecified
I68 Cerebrovascular disorders in diseases classified elsewhere
I68.0 Cerebral amyloid angiopathy
I68.2 Cerebral arteritis in other diseases classified elsewhere
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
I69 Sequelae of cerebrovascular disease
I69.0 Sequelae of nontraumatic subarachnoid hemorrhage
I69.00 Unspecified sequelae of nontraumatic subarachnoid hemorrhage
I69.01 Cognitive deficits following nontraumatic subarachnoid hemorrhage
I69.010 Attention and concentration deficit following nontraumatic subarachnoid hemorrhage
I69.011 Memory deficit following nontraumatic subarachnoid hemorrhage
I69.012 Visuospatial deficit and spatial neglect following nontraumatic subarachnoid hemorrhage
I69.013 Psychomotor deficit following nontraumatic subarachnoid hemorrhage

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.