1. ICD-10-CM Codes
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2. K00-K95 Diseases of the digestive system
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3. K70-K77 Diseases of liver
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4. K72- Hepatic failure, not elsewhere classified
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5. 2021 ICD-10-CM Diagnosis Code K72.0

2021 ICD-10-CM Diagnosis Code K72.0

Acute and subacute hepatic failure

2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code

• K72.0 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
• The 2021 edition of ICD-10-CM K72.0 became effective on October 1, 2020.
• This is the American ICD-10-CM version of K72.0 - other international versions of ICD-10 K72.0 may differ.

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change
• 2021 (effective 10/1/2020): No change

• Code Also: M35.81
  ICD-10-CM Diagnosis Code M35.81

  Multisystem inflammatory syndrome

  2021 - New Code Billable/Specific Code

  Applicable To

  • MIS-A
  • MIS-C
  • Multisystem inflammatory syndrome in adults
  • Multisystem inflammatory syndrome in children
  • Pediatric inflammatory multisystem syndrome
  • PIMS

  Code First

  • , if applicable, COVID-19 (U07.1)

  Code Also

  • any associated complications such as:
  • acute hepatic failure (K72.0-)
  • acute kidney failure (N17.-)
  • acute myocarditis (I40.-)
  • acute respiratory distress syndrome (J80)
  • cardiac arrhythmia (I47-I49.-)
  • pneumonia due to COVID-19 (J12.82)
  • severe sepsis (R65.2-)
  • viral cardiomyopathy (B33.24)
  • viral pericarditis (B33.23)

  Use Additional

  • code, if applicable, for:
  • exposure to COVID-19 or SARS-CoV-2 infection (Z20.822)
  • personal history of COVID-19 (Z86.16)
  • sequelae of COVID-19 (B94.8)
• Type 1 Excludes: K75.2
  , K75.3
  , K75.9
  ICD-10-CM Diagnosis Code K75.2

  Nonspecific reactive hepatitis

  2016 2017 2018 2019 2020 2021 Billable/Specific Code

  Type 1 Excludes

  • acute or subacute hepatitis (K72.0-)
  • chronic hepatitis NEC (K73.-)
  • viral hepatitis (B15-B19)
  ICD-10-CM Diagnosis Code K75.3

  Granulomatous hepatitis, not elsewhere classified

  2016 2017 2018 2019 2020 2021 Billable/Specific Code

  Type 1 Excludes

  • acute or subacute hepatitis (K72.0-)
  • chronic hepatitis NEC (K73.-)
  • viral hepatitis (B15-B19)
  ICD-10-CM Diagnosis Code K75.9

  Inflammatory liver disease, unspecified

  2016 2017 2018 2019 2020 2021 Billable/Specific Code

  Applicable To

  • Hepatitis NOS

  Type 1 Excludes

  • acute or subacute hepatitis (K72.0-)
  • chronic hepatitis NEC (K73.-)
  • viral hepatitis (B15-B19)
• Type 2 Excludes: K75.0
  ICD-10-CM Diagnosis Code K75.0

  Abscess of liver

  2016 2017 2018 2019 2020 2021 Billable/Specific Code

  Applicable To

  • Cholangitic hepatic abscess
  • Hematogenic hepatic abscess
  • Hepatic abscess NOS
  • Lymphogenic hepatic abscess
  • Pylephlebitic hepatic abscess

  Type 1 Excludes

  • amebic liver abscess (A06.4)
  • cholangitis without liver abscess (K83.09)
  • pylephlebitis without liver abscess (K75.1)

  Type 2 Excludes

  • acute or subacute hepatitis NOS (B17.9)
  • acute or subacute non-viral hepatitis (K72.0)
  • chronic hepatitis NEC (K73.8)
• Use Additional: R65.11
  , R65.2
  ICD-10-CM Diagnosis Code R65.11

  Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction

  2016 2017 2018 2019 2020 2021 Billable/Specific Code

  Use Additional

  • code to identify specific acute organ dysfunction, such as:
  • acute kidney failure (N17.-)
  • acute respiratory failure (J96.0-)
  • critical illness myopathy (G72.81)
  • critical illness polyneuropathy (G62.81)
  • disseminated intravascular coagulopathy [DIC] (D65)
  • encephalopathy (metabolic) (septic) (G93.41)
  • hepatic failure (K72.0-)
  ICD-10-CM Diagnosis Code R65.2

  Severe sepsis

  2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code

  Applicable To

  • Infection with associated acute organ dysfunction
  • Sepsis with acute organ dysfunction
  • Sepsis with multiple organ dysfunction
  • Systemic inflammatory response syndrome due to infectious process with acute organ dysfunction

  Code First

  • underlying infection, such as:
  • infection following a procedure (T81.4-)
  • infections following infusion, transfusion and therapeutic injection (T80.2-)
  • puerperal sepsis (O85)
  • sepsis following complete or unspecified spontaneous abortion (O03.87)
  • sepsis following ectopic and molar pregnancy (O08.82)
  • sepsis following incomplete spontaneous abortion (O03.37)
  • sepsis following (induced) termination of pregnancy (O04.87)
  • sepsis NOS (A41.9)

  Use Additional

  • code to identify specific acute organ dysfunction, such as:
  • acute kidney failure (N17.-)
  • acute respiratory failure (J96.0-)
  • critical illness myopathy (G72.81)
  • critical illness polyneuropathy (G62.81)
  • disseminated intravascular coagulopathy [DIC] (D65)
  • encephalopathy (metabolic) (septic) (G93.41)
  • hepatic failure (K72.0-)

• Hepatitis K75.9
  ICD-10-CM Diagnosis Code K75.9

  Inflammatory liver disease, unspecified

  2016 2017 2018 2019 2020 2021 Billable/Specific Code

  Applicable To

  • Hepatitis NOS

  Type 1 Excludes

  • acute or subacute hepatitis (K72.0-)
  • chronic hepatitis NEC (K73.-)
  • viral hepatitis (B15-B19)
  • acute B17.9
    ICD-10-CM Diagnosis Code B17.9

    Acute viral hepatitis, unspecified

    2016 2017 2018 2019 2020 2021 Billable/Specific Code

    Applicable To

    • Acute hepatitis NOS
    • Acute infectious hepatitis NOS
    • non-viral K72.0

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.