2021 ICD-10-CM Diagnosis Code K75.4

Autoimmune hepatitis

    2016 2017 2018 2019 2020 2021 Billable/Specific Code
  • K75.4 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2021 edition of ICD-10-CM K75.4 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of K75.4 - other international versions of ICD-10 K75.4 may differ.
Applicable To
  • Lupoid hepatitis NEC
The following code(s) above K75.4 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to K75.4:
  • K00-K95
    2021 ICD-10-CM Range K00-K95

    Diseases of the digestive system

    Type 2 Excludes
    • certain conditions originating in the perinatal period (P04-P96)
    • certain infectious and parasitic diseases (A00-B99)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the digestive system
  • K70-K77
    2021 ICD-10-CM Range K70-K77

    Diseases of liver

    Type 1 Excludes
    • jaundice NOS (R17)
    Type 2 Excludes
    Diseases of liver
  • K75
    ICD-10-CM Diagnosis Code K75

    Other inflammatory liver diseases

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 2 Excludes
    • toxic liver disease (K71.-)
    Other inflammatory liver diseases
Approximate Synonyms
  • Autoimmune hepatitis, chronic
  • Chronic active hepatitis
  • Chronic autoimmune hepatitis
  • Lupus hepatitis
Clinical Information
  • A chronic self-perpetuating hepatocellular inflammation of unknown cause, usually with hypergammaglobulinemia and serum autoantibodies.
  • Hepatitis caused by autoantibodies. Drugs, infections, and toxins may trigger the production of the autoantibodies against the liver parenchyma.
ICD-10-CM K75.4 is grouped within Diagnostic Related Group(s) (MS-DRG v38.0):
  • 441 Disorders of liver except malignancy, cirrhosis or alcoholic hepatitis with mcc
  • 442 Disorders of liver except malignancy, cirrhosis or alcoholic hepatitis with cc
  • 443 Disorders of liver except malignancy, cirrhosis or alcoholic hepatitis without cc/mcc

Convert K75.4 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change

Diagnosis Index entries containing back-references to K75.4:
  • Hepatitis K75.9
    ICD-10-CM Diagnosis Code K75.9

    Inflammatory liver disease, unspecified

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Hepatitis NOS
    Type 1 Excludes
    • acute or subacute hepatitis (K72.0-)
    • chronic hepatitis NEC (K73.-)
    • viral hepatitis (B15-B19)
    • autoimmune K75.4
    • lupoid NEC K75.4

ICD-10-CM Codes Adjacent To K75.4
K74.4 Secondary biliary cirrhosis
K74.5 Biliary cirrhosis, unspecified
K74.6 Other and unspecified cirrhosis of liver
K74.60 Unspecified cirrhosis of liver
K74.69 Other cirrhosis of liver
K75 Other inflammatory liver diseases
K75.0 Abscess of liver
K75.1 Phlebitis of portal vein
K75.2 Nonspecific reactive hepatitis
K75.3 Granulomatous hepatitis, not elsewhere classified
K75.4 Autoimmune hepatitis
K75.8 Other specified inflammatory liver diseases
K75.81 Nonalcoholic steatohepatitis (NASH)
K75.89 Other specified inflammatory liver diseases
K75.9 Inflammatory liver disease, unspecified
K76 Other diseases of liver
K76.0 Fatty (change of) liver, not elsewhere classified
K76.1 Chronic passive congestion of liver
K76.2 Central hemorrhagic necrosis of liver
K76.3 Infarction of liver
K76.4 Peliosis hepatis

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.