2023 ICD-10-CM Diagnosis Code L12.31

Epidermolysis bullosa due to drug

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • L12.31 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2023 edition of ICD-10-CM L12.31 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of L12.31 - other international versions of ICD-10 L12.31 may differ.
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Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • code for adverse effect, if applicable, to identify drug (T36-T50
    ICD-10-CM Range T36-T50

    Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances

    Code First
    • , for adverse effects, the nature of the adverse effect, such as:
    • adverse effect NOS (T88.7)
    • aspirin gastritis (K29.-)
    • blood disorders (D56-D76)
    • contact dermatitis (L23-L25)
    • dermatitis due to substances taken internally (L27.-)
    • nephropathy (N14.0-N14.2)
    Includes
    • adverse effect of correct substance properly administered
    • poisoning by overdose of substance
    • poisoning by wrong substance given or taken in error
    • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
    Note
    • The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
    Type 1 Excludes
    • toxic reaction to local anesthesia in pregnancy (O29.3-)
    Type 2 Excludes
    • abuse and dependence of psychoactive substances (F10-F19)
    • abuse of non-dependence-producing substances (F55.-)
    • immunodeficiency due to drugs (D84.821)
    • drug reaction and poisoning affecting newborn (P00-P96)
    • pathological drug intoxication (inebriation) (F10-F19)
    Use Additional
    • code(s) to specify:
    • manifestations of poisoning
    • underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
    • underdosing of medication regimen (Z91.12-, Z91.13-)
    • T36 Poisoning by, adverse effect of and unde...
    • T37 Poisoning by, adverse effect of and unde...
    • T38 Poisoning by, adverse effect of and unde...
    • T39 Poisoning by, adverse effect of and unde...
    • T40 Poisoning by, adverse effect of and unde...
    • T41 Poisoning by, adverse effect of and unde...
    • T42 Poisoning by, adverse effect of and unde...
    • T43 Poisoning by, adverse effect of and unde...
    • T44 Poisoning by, adverse effect of and unde...
    • T45 Poisoning by, adverse effect of and unde...
    • T46 Poisoning by, adverse effect of and unde...
    • T47 Poisoning by, adverse effect of and unde...
    • T48 Poisoning by, adverse effect of and unde...
    • T49 Poisoning by, adverse effect of and unde...
    • T50 Poisoning by, adverse effect of and unde...
    with fifth or sixth character 5)
The following code(s) above L12.31 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to L12.31:
  • L00-L99
    2023 ICD-10-CM Range L00-L99

    Diseases of the skin and subcutaneous tissue

    Type 2 Excludes
    • certain conditions originating in the perinatal period (P04-P96)
    • certain infectious and parasitic diseases (A00-B99)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • lipomelanotic reticulosis (I89.8)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    • systemic connective tissue disorders (M30-M36)
    • viral warts (B07.-)
    Diseases of the skin and subcutaneous tissue
  • L10-L14
    2023 ICD-10-CM Range L10-L14

    Bullous disorders

    Type 1 Excludes
    • benign familial pemphigus [Hailey-Hailey] (Q82.8)
    • staphylococcal scalded skin syndrome (L00)
    • toxic epidermal necrolysis [Lyell] (L51.2)
    Bullous disorders
  • L12
    ICD-10-CM Diagnosis Code L12

    Pemphigoid

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • herpes gestationis (O26.4-)
    • impetigo herpetiformis (L40.1)
    Pemphigoid
  • L12.3
    ICD-10-CM Diagnosis Code L12.3

    Acquired epidermolysis bullosa

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • epidermolysis bullosa (congenital) (Q81.-)
    Acquired epidermolysis bullosa
Approximate Synonyms
  • Drug induced epidermolysis bullosa
  • Drug-induced epidermolysis bullosa acquisita
ICD-10-CM L12.31 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 595 Major skin disorders with mcc
  • 596 Major skin disorders without mcc

Convert L12.31 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change

Diagnosis Index entries containing back-references to L12.31:
  • Epidermolysis
    • bullosa (congenital) Q81.9
      ICD-10-CM Diagnosis Code Q81.9

      Epidermolysis bullosa, unspecified

        2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code POA Exempt
      • acquired L12.30
        ICD-10-CM Diagnosis Code L12.30

        Acquired epidermolysis bullosa, unspecified

          2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
        • drug-induced L12.31

ICD-10-CM Codes Adjacent To L12.31
L11.0 Acquired keratosis follicularis
L11.1 Transient acantholytic dermatosis [Grover]
L11.8 Other specified acantholytic disorders
L11.9 Acantholytic disorder, unspecified
L12 Pemphigoid
L12.0 Bullous pemphigoid
L12.1 Cicatricial pemphigoid
L12.2 Chronic bullous disease of childhood
L12.3 Acquired epidermolysis bullosa
L12.30 …… unspecified
L12.31 Epidermolysis bullosa due to drug
L12.35 Other acquired epidermolysis bullosa
L12.8 Other pemphigoid
L12.9 Pemphigoid, unspecified
L13 Other bullous disorders
L13.0 Dermatitis herpetiformis
L13.1 Subcorneal pustular dermatitis
L13.8 Other specified bullous disorders
L13.9 Bullous disorder, unspecified
L14 Bullous disorders in diseases classified elsewhere
L20 Atopic dermatitis

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.