2022 ICD-10-CM Diagnosis Code L25.1

Unspecified contact dermatitis due to drugs in contact with skin

    2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
  • L25.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • Short description: Unsp contact dermatitis due to drugs in contact with skin
  • The 2022 edition of ICD-10-CM L25.1 became effective on October 1, 2021.
  • This is the American ICD-10-CM version of L25.1 - other international versions of ICD-10 L25.1 may differ.
Use Additional
Use Additional Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • code for adverse effect, if applicable, to identify drug (T36-T50
    ICD-10-CM Range T36-T50

    Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances

    Code First
    • , for adverse effects, the nature of the adverse effect, such as:
    • adverse effect NOS (T88.7)
    • aspirin gastritis (K29.-)
    • blood disorders (D56-D76)
    • contact dermatitis (L23-L25)
    • dermatitis due to substances taken internally (L27.-)
    • nephropathy (N14.0-N14.2)
    Includes
    • adverse effect of correct substance properly administered
    • poisoning by overdose of substance
    • poisoning by wrong substance given or taken in error
    • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
    Note
    • The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
    Type 1 Excludes
    • toxic reaction to local anesthesia in pregnancy (O29.3-)
    Type 2 Excludes
    • abuse and dependence of psychoactive substances (F10-F19)
    • abuse of non-dependence-producing substances (F55.-)
    • immunodeficiency due to drugs (D84.821)
    • drug reaction and poisoning affecting newborn (P00-P96)
    • pathological drug intoxication (inebriation) (F10-F19)
    Use Additional
    • code(s) to specify:
    • manifestations of poisoning
    • underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
    • underdosing of medication regimen (Z91.12-, Z91.13-)
    • T36 Poisoning by, adverse effect of and unde...
    • T37 Poisoning by, adverse effect of and unde...
    • T38 Poisoning by, adverse effect of and unde...
    • T39 Poisoning by, adverse effect of and unde...
    • T40 Poisoning by, adverse effect of and unde...
    • T41 Poisoning by, adverse effect of and unde...
    • T42 Poisoning by, adverse effect of and unde...
    • T43 Poisoning by, adverse effect of and unde...
    • T44 Poisoning by, adverse effect of and unde...
    • T45 Poisoning by, adverse effect of and unde...
    • T46 Poisoning by, adverse effect of and unde...
    • T47 Poisoning by, adverse effect of and unde...
    • T48 Poisoning by, adverse effect of and unde...
    • T49 Poisoning by, adverse effect of and unde...
    • T50 Poisoning by, adverse effect of and unde...
    with fifth or sixth character 5)
Type 2 Excludes
Type 2 Excludes Help
A type 2 excludes note represents "not included here". A type 2 excludes note indicates that the condition excluded is not part of the condition it is excluded from but a patient may have both conditions at the same time. When a type 2 excludes note appears under a code it is acceptable to use both the code (L25.1) and the excluded code together.
  • dermatitis due to ingested drugs and medicaments (
    ICD-10-CM Diagnosis Code L27.0

    Generalized skin eruption due to drugs and medicaments taken internally

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    Use Additional
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
    L27.0-
    ICD-10-CM Diagnosis Code L27.1

    Localized skin eruption due to drugs and medicaments taken internally

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    Use Additional
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
    L27.1
    )
The following code(s) above L25.1 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to L25.1:
  • L00-L99
    2022 ICD-10-CM Range L00-L99

    Diseases of the skin and subcutaneous tissue

    Type 2 Excludes
    • certain conditions originating in the perinatal period (P04-P96)
    • certain infectious and parasitic diseases (A00-B99)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • lipomelanotic reticulosis (I89.8)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    • systemic connective tissue disorders (M30-M36)
    • viral warts (B07.-)
    Diseases of the skin and subcutaneous tissue
  • L20-L30
    2022 ICD-10-CM Range L20-L30

    Dermatitis and eczema

    Note
    • In this block the terms dermatitis and eczema are used synonymously and interchangeably.
    Type 2 Excludes
    • chronic (childhood) granulomatous disease (D71)
    • dermatitis gangrenosa (L08.0)
    • dermatitis herpetiformis (L13.0)
    • dry skin dermatitis (L85.3)
    • factitial dermatitis (L98.1)
    • perioral dermatitis (L71.0)
    • radiation-related disorders of the skin and subcutaneous tissue (L55-L59)
    • stasis dermatitis (I87.2)
    Dermatitis and eczema
  • L25
    ICD-10-CM Diagnosis Code L25

    Unspecified contact dermatitis

      2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • allergic contact dermatitis (L23.-)
    • allergy NOS (T78.40)
    • dermatitis NOS (L30.9)
    • irritant contact dermatitis (L24.-)
    Type 2 Excludes
    • dermatitis due to ingested substances (L27.-)
    • dermatitis of eyelid (H01.1-)
    • eczema of external ear (H60.5-)
    • perioral dermatitis (L71.0)
    • radiation-related disorders of the skin and subcutaneous tissue (L55-L59)
    Unspecified contact dermatitis
Approximate Synonyms
  • Contact dermatitis due to drug
  • Contact dermatitis due to drugs and/or medicine
ICD-10-CM L25.1 is grouped within Diagnostic Related Group(s) (MS-DRG v39.0):
  • 606 Minor skin disorders with mcc
  • 607 Minor skin disorders without mcc

Convert L25.1 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
Code annotations containing back-references to L25.1:
  • Type 2 Excludes: T88
    , T81
    ICD-10-CM Diagnosis Code T88

    Other complications of surgical and medical care, not elsewhere classified

      2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
    Type 2 Excludes
    • complication following infusion, transfusion and therapeutic injection (T80.-)
    • complication following procedure NEC (T81.-)
    • complications of anesthesia in labor and delivery (O74.-)
    • complications of anesthesia in pregnancy (O29.-)
    • complications of anesthesia in puerperium (O89.-)
    • complications of devices, implants and grafts (T82-T85)
    • complications of obstetric surgery and procedure (O75.4)
    • dermatitis due to drugs and medicaments (L23.3, L24.4, L25.1, L27.0-L27.1)
    • poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
    • specified complications classified elsewhere
    ICD-10-CM Diagnosis Code T81

    Complications of procedures, not elsewhere classified

      2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
    Type 2 Excludes
    Use Additional
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Diagnosis Index entries containing back-references to L25.1:
  • Dermatitis (eczematous) L30.9
    ICD-10-CM Diagnosis Code L30.9

    Dermatitis, unspecified

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    Applicable To
    • Eczema NOS
    • contact (occupational) L25.9
      ICD-10-CM Diagnosis Code L25.9

      Unspecified contact dermatitis, unspecified cause

        2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
      Applicable To
      • Contact dermatitis (occupational) NOS
      • Contact eczema (occupational) NOS
      • due to
        • drugs in contact with skin L25.1
    • due to
      • drugs and medicaments (generalized) (internal use) L27.0
        ICD-10-CM Diagnosis Code L27.0

        Generalized skin eruption due to drugs and medicaments taken internally

          2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
        Use Additional
        • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • Rash (toxic) R21
    ICD-10-CM Diagnosis Code R21

    Rash and other nonspecific skin eruption

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    Includes
    • rash NOS
    Type 1 Excludes
    • specified type of rash- code to condition
    • vesicular eruption (R23.8)
    • drug (internal use) L27.0
      ICD-10-CM Diagnosis Code L27.0

      Generalized skin eruption due to drugs and medicaments taken internally

        2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
      Use Additional
      • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

ICD-10-CM Codes Adjacent To L25.1
L24.A1 Irritant contact dermatitis due to saliva
L24.A2 Irritant contact dermatitis due to fecal, urinary or dual incontinence
L24.A9 Irritant contact dermatitis due friction or contact with other specified body fluids
L24.B Irritant contact dermatitis related to stoma or fistula
L24.B0 Irritant contact dermatitis related to unspecified stoma or fistula
L24.B1 Irritant contact dermatitis related to digestive stoma or fistula
L24.B2 Irritant contact dermatitis related to respiratory stoma or fistula
L24.B3 Irritant contact dermatitis related to fecal or urinary stoma or fistula
L25 Unspecified contact dermatitis
L25.0 Unspecified contact dermatitis due to cosmetics
L25.1 Unspecified contact dermatitis due to drugs in contact with skin
L25.2 Unspecified contact dermatitis due to dyes
L25.3 Unspecified contact dermatitis due to other chemical products
L25.4 Unspecified contact dermatitis due to food in contact with skin
L25.5 Unspecified contact dermatitis due to plants, except food
L25.8 Unspecified contact dermatitis due to other agents
L25.9 Unspecified contact dermatitis, unspecified cause
L26 Exfoliative dermatitis
L27 Dermatitis due to substances taken internally
L27.0 Generalized skin eruption due to drugs and medicaments taken internally
L27.1 Localized skin eruption due to drugs and medicaments taken internally

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.