ICD-10-CM Codes
L00-L99
L20-L30
L27-
2023 ICD-10-CM Diagnosis Code L27.1

2023 ICD-10-CM Diagnosis Code L27.1

Localized skin eruption due to drugs and medicaments taken internally

2016

2017

2018

2019

2020

2021

2022

2023

Billable/Specific Code

L27.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
Short description: Loc skin eruption due to drugs and meds taken internally
The 2023 edition of ICD-10-CM L27.1 became effective on October 1, 2022.
This is the American ICD-10-CM version of L27.1 - other international versions of ICD-10 L27.1 may differ.

Use Additional

Use Additional Help

Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.

code for adverse effect, if applicable, to identify drug (T36-T50
ICD-10-CM Range T36-T50
Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
Code First
- , for adverse effects, the nature of the adverse effect, such as:
- adverse effect NOS (T88.7)
- aspirin gastritis (K29.-)
- blood disorders (D56-D76)
- contact dermatitis (L23-L25)
- dermatitis due to substances taken internally (L27.-)
- nephropathy (N14.0-N14.2)
Includes
- adverse effect of correct substance properly administered
- poisoning by overdose of substance
- poisoning by wrong substance given or taken in error
- underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
Note
- The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
Type 1 Excludes
- toxic reaction to local anesthesia in pregnancy (O29.3-)
Type 2 Excludes
- abuse and dependence of psychoactive substances (F10-F19)
- abuse of non-dependence-producing substances (F55.-)
- immunodeficiency due to drugs (D84.821)
- drug reaction and poisoning affecting newborn (P00-P96)
- pathological drug intoxication (inebriation) (F10-F19)
Use Additional
- code(s) to specify:
- manifestations of poisoning
- underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
- underdosing of medication regimen (Z91.12-, Z91.13-)
- T36 Poisoning by, adverse effect of and unde...
- T37 Poisoning by, adverse effect of and unde...
- T38 Poisoning by, adverse effect of and unde...
- T39 Poisoning by, adverse effect of and unde...
- T40 Poisoning by, adverse effect of and unde...
- T41 Poisoning by, adverse effect of and unde...
- T42 Poisoning by, adverse effect of and unde...
- T43 Poisoning by, adverse effect of and unde...
- T44 Poisoning by, adverse effect of and unde...
- T45 Poisoning by, adverse effect of and unde...
- T46 Poisoning by, adverse effect of and unde...
- T47 Poisoning by, adverse effect of and unde...
- T48 Poisoning by, adverse effect of and unde...
- T49 Poisoning by, adverse effect of and unde...
- T50 Poisoning by, adverse effect of and unde...
with fifth or sixth character 5)

The following code(s) above L27.1 contain annotation back-references

Annotation Back-References

In this context, annotation back-references refer to codes that contain:

Applicable To annotations, or
Code Also annotations, or
Code First annotations, or
Excludes1 annotations, or
Excludes2 annotations, or
Includes annotations, or
Note annotations, or
Use Additional annotations

that may be applicable to L27.1:

L00-L99
2023 ICD-10-CM Range L00-L99
Diseases of the skin and subcutaneous tissue
Type 2 Excludes
- certain conditions originating in the perinatal period (P04-P96)
- certain infectious and parasitic diseases (A00-B99)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- lipomelanotic reticulosis (I89.8)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
- systemic connective tissue disorders (M30-M36)
- viral warts (B07.-)
Diseases of the skin and subcutaneous tissue
L20-L30
2023 ICD-10-CM Range L20-L30
Dermatitis and eczema
Note
- In this block the terms dermatitis and eczema are used synonymously and interchangeably.
Type 2 Excludes
- chronic (childhood) granulomatous disease (D71)
- dermatitis gangrenosa (L08.0)
- dermatitis herpetiformis (L13.0)
- dry skin dermatitis (L85.3)
- factitial dermatitis (L98.1)
- perioral dermatitis (L71.0)
- radiation-related disorders of the skin and subcutaneous tissue (L55-L59)
- stasis dermatitis (I87.2)
Dermatitis and eczema
L27
ICD-10-CM Diagnosis Code L27
Dermatitis due to substances taken internally
Type 1 Excludes
- allergy NOS (T78.40)
Type 2 Excludes
- adverse food reaction, except dermatitis (T78.0-T78.1)
- contact dermatitis (L23-L25)
- drug photoallergic response (L56.1)
- drug phototoxic response (L56.0)
- urticaria (L50.-)
Dermatitis due to substances taken internally

Approximate Synonyms

Localized dermatitis due to drug taken internally

ICD-10-CM L27.1 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):

606 Minor skin disorders with mcc
607 Minor skin disorders without mcc
791 Prematurity with major problems
793 Full term neonate with major problems

Convert L27.1 to ICD-9-CM

Code History

2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
2017 (effective 10/1/2016): No change
2018 (effective 10/1/2017): No change
2019 (effective 10/1/2018): No change
2020 (effective 10/1/2019): No change
2021 (effective 10/1/2020): No change
2022 (effective 10/1/2021): No change
2023 (effective 10/1/2022): No change

Code annotations containing back-references to L27.1:

Type 2 Excludes: T81
, T88
, L25.1
, L23.3

ICD-10-CM Diagnosis Code T81
Complications of procedures, not elsewhere classified
Type 2 Excludes
- complications following immunization (T88.0-T88.1)
- complications following infusion, transfusion and therapeutic injection (T80.-)
- complications of transplanted organs and tissue (T86.-)
- specified complications classified elsewhere, such as:
- complication of prosthetic devices, implants and grafts (T82-T85)
- dermatitis due to drugs and medicaments (L23.3, L24.4, L25.1, L27.0-L27.1)
- endosseous dental implant failure (M27.6-)
- floppy iris syndrome (IFIS) (intraoperative) H21.81
- intraoperative and postprocedural complications of specific body system (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95, K91.-, L76.-, M96.-, N99.-)
- ostomy complications (J95.0-, K94.-, N99.5-)
- plateau iris syndrome (post-iridectomy) (postprocedural) H21.82
- poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
Use Additional
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
ICD-10-CM Diagnosis Code T88
Other complications of surgical and medical care, not elsewhere classified
Type 2 Excludes
- complication following infusion, transfusion and therapeutic injection (T80.-)
- complication following procedure NEC (T81.-)
- complications of anesthesia in labor and delivery (O74.-)
- complications of anesthesia in pregnancy (O29.-)
- complications of anesthesia in puerperium (O89.-)
- complications of devices, implants and grafts (T82-T85)
- complications of obstetric surgery and procedure (O75.4)
- dermatitis due to drugs and medicaments (L23.3, L24.4, L25.1, L27.0-L27.1)
- poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
- specified complications classified elsewhere
ICD-10-CM Diagnosis Code L25.1
Unspecified contact dermatitis due to drugs in contact with skin
Type 2 Excludes
- dermatitis due to ingested drugs and medicaments (L27.0-L27.1)
Use Additional
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
ICD-10-CM Diagnosis Code L23.3
Allergic contact dermatitis due to drugs in contact with skin
Type 2 Excludes
- dermatitis due to ingested drugs and medicaments (L27.0-L27.1)
Use Additional
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Diagnosis Index entries containing back-references to L27.1:

Dermatitis (eczematous) L30.9
ICD-10-CM Diagnosis Code L30.9
Dermatitis, unspecified
Applicable To
Eczema NOS
- due to
  - drugs and medicaments (generalized) (internal use) L27.0
    ICD-10-CM Diagnosis Code L27.0
    Generalized skin eruption due to drugs and medicaments taken internally
    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Use Additional
    code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
    - localized skin eruption L27.1
Eruption
- drug (generalized) (taken internally) L27.0
  ICD-10-CM Diagnosis Code L27.0
  Generalized skin eruption due to drugs and medicaments taken internally
  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  Use Additional
  code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  - fixed L27.1
  - localized L27.1
- skin (nonspecific) R21
  ICD-10-CM Diagnosis Code R21
  Rash and other nonspecific skin eruption
  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  Includes
  rash NOS
  Type 1 Excludes
  specified type of rash- code to condition
  vesicular eruption (R23.8)
  - due to inoculation/vaccination (generalized) L27.0
    - see also Dermatitis, due to, vaccine
    ICD-10-CM Diagnosis Code L27.0
    Generalized skin eruption due to drugs and medicaments taken internally
    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Use Additional
    code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
    - localized L27.1
Erythrodysesthesia, palmar plantar L27.1 (PPE)
Hand-foot syndrome L27.1
Syndrome - see also Disease
- hand-foot L27.1

ICD-10-CM Codes Adjacent To L27.1

L25.1 Unspecified contact dermatitis due to drugs in contact with skin

L25.2 Unspecified contact dermatitis due to dyes

L25.3 Unspecified contact dermatitis due to other chemical products

L25.4 Unspecified contact dermatitis due to food in contact with skin

L25.5 Unspecified contact dermatitis due to plants, except food

L25.8 Unspecified contact dermatitis due to other agents

L25.9 Unspecified contact dermatitis, unspecified cause

L26 Exfoliative dermatitis

L27 Dermatitis due to substances taken internally

L27.0 Generalized skin eruption due to drugs and medicaments taken internally

L27.1 Localized skin eruption due to drugs and medicaments taken internally

L27.2 Dermatitis due to ingested food

L27.8 Dermatitis due to other substances taken internally

L27.9 Dermatitis due to unspecified substance taken internally

L28 Lichen simplex chronicus and prurigo

L28.0 Lichen simplex chronicus

L28.1 Prurigo nodularis

L28.2 Other prurigo

L29 Pruritus

L29.0 Pruritus ani

L29.1 Pruritus scroti

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

2023 ICD-10-CM Diagnosis Code L27.1

Localized skin eruption due to drugs and medicaments taken internally

Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances

Diseases of the skin and subcutaneous tissue

Dermatitis and eczema

Dermatitis due to substances taken internally

Complications of procedures, not elsewhere classified

Other complications of surgical and medical care, not elsewhere classified

Unspecified contact dermatitis due to drugs in contact with skin

Allergic contact dermatitis due to drugs in contact with skin

Dermatitis, unspecified

Generalized skin eruption due to drugs and medicaments taken internally

Generalized skin eruption due to drugs and medicaments taken internally

Rash and other nonspecific skin eruption

Generalized skin eruption due to drugs and medicaments taken internally