1. ICD-10-CM Codes
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2. L00-L99
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3. L49-L54
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4. L51-
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5. 2023 ICD-10-CM Diagnosis Code L51.2

2023 ICD-10-CM Diagnosis Code L51.2

Toxic epidermal necrolysis [Lyell]

2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

• L51.2 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
• The 2023 edition of ICD-10-CM L51.2 became effective on October 1, 2022.
• This is the American ICD-10-CM version of L51.2 - other international versions of ICD-10 L51.2 may differ.

• Lyell's toxic epidermal necrolysis, subepidermal type
• Toxic epidermal necrolysis

• A disorder characterized by greater than 30% total body skin area separation of dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin and the mucous membranes.
• A systemic, serious, and life-threatening disorder characterized by erythematous and necrotic lesions in the skin and mucous membranes that are associated with bullous detachment of the epidermis. The epidermal and mucous membranes detachment leads to sepsis and may be fatal. The lesions appear throughout the body and occupy more than 30% of the body surfaces. It is a hypersensitivity reaction usually caused by drugs (e.g., sulfonamides, nonsteroidal anti-inflammatory drugs, anticonvulsants, and antiretroviral drugs).
• An exfoliative disease of skin seen primarily in adults and characterized by flaccid bullae and spreading erythema so that the skin has the appearance of being scalded. It results primarily from a toxic reaction to various drugs, but occasionally occurs as a result of infection, neoplastic conditions, or other exposure.
• An exfoliative skin disease caused by a toxic reaction to drugs, infections, and substance exposure.

• 595 Major skin disorders with mcc
• 596 Major skin disorders without mcc

Convert L51.2 to ICD-9-CM

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change
• 2021 (effective 10/1/2020): No change
• 2022 (effective 10/1/2021): No change
• 2023 (effective 10/1/2022): No change

• Code First: L49
  ICD-10-CM Diagnosis Code L49

  Exfoliation due to erythematous conditions according to extent of body surface involved

  2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code

  Code First

  • erythematous condition causing exfoliation, such as:
  • Ritter's disease (L00)
  • (Staphylococcal) scalded skin syndrome (L00)
  • Stevens-Johnson syndrome (L51.1)
  • Stevens-Johnson syndrome-toxic epidermal necrolysis
  • overlap syndrome (L51.3)
  • Toxic epidermal necrolysis (L51.2)
• Type 1 Excludes: L00
  ICD-10-CM Diagnosis Code L00

  Staphylococcal scalded skin syndrome

  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

  Applicable To

  • Ritter's disease

  Type 1 Excludes

  • bullous impetigo (L01.03)
  • pemphigus neonatorum (L01.03)
  • toxic epidermal necrolysis [Lyell] (L51.2)

  Use Additional

  • code to identify percentage of skin exfoliation (L49.-)

• Epidermolysis
  • necroticans combustiformis L51.2
• Lyell's syndrome L51.2
  • due to drug L51.2
• Necrolysis, toxic epidermal L51.2

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.