2021 ICD-10-CM Diagnosis Code M04.8

Other autoinflammatory syndromes

    2017 - New Code 2018 2019 2020 2021 Billable/Specific Code
  • M04.8 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2021 edition of ICD-10-CM M04.8 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of M04.8 - other international versions of ICD-10 M04.8 may differ.
Applicable To
  • Blau syndrome
  • Deficiency of interleukin 1 receptor antagonist [DIRA]
  • Majeed syndrome
  • Periodic fever, aphthous stomatitis, pharyngitis, and adenopathy syndrome [PFAPA]
  • Pyogenic arthritis, pyoderma gangrenosum, and acne syndrome [PAPA]
The following code(s) above M04.8 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to M04.8:
  • M00-M99
    2021 ICD-10-CM Range M00-M99

    Diseases of the musculoskeletal system and connective tissue

    Note
    • Use an external cause code following the code for the musculoskeletal condition, if applicable, to identify the cause of the musculoskeletal condition
    Type 2 Excludes
    • arthropathic psoriasis (L40.5-)
    • certain conditions originating in the perinatal period (P04-P96)
    • certain infectious and parasitic diseases (A00-B99)
    • compartment syndrome (traumatic) (T79.A-)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the musculoskeletal system and connective tissue
  • M04
    ICD-10-CM Diagnosis Code M04

    Autoinflammatory syndromes

      2017 - New Code 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 2 Excludes
    Autoinflammatory syndromes
ICD-10-CM M04.8 is grouped within Diagnostic Related Group(s) (MS-DRG v38.0):
  • 545 Connective tissue disorders with mcc
  • 546 Connective tissue disorders with cc
  • 547 Connective tissue disorders without cc/mcc

Convert M04.8 to ICD-9-CM

Code History
  • 2017 (effective 10/1/2016): New code
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change

Diagnosis Index entries containing back-references to M04.8:
  • Deficiency, deficient
    • of interleukin 1 receptor antagonist [DIRA] M04.8
  • DIRA M04.8 (deficiency of interleukin 1 receptor antagonist)
  • Disease, diseased - see also Syndrome
    • autoinflammatory M04.9
      ICD-10-CM Diagnosis Code M04.9

      Autoinflammatory syndrome, unspecified

        2017 - New Code 2018 2019 2020 2021 Billable/Specific Code
      • NOD2-associated M04.8
      • specified type NEC M04.8
  • PAPA M04.8 (pyogenic arthritis, pyoderma gangrenosum, and acne syndrome)
  • PFAPA M04.8 (periodic fever, aphthous stomatitis, pharyngitis, and adenopathy syndrome)
  • Syndrome - see also Disease
    • autoinflammatory M04.9
      ICD-10-CM Diagnosis Code M04.9

      Autoinflammatory syndrome, unspecified

        2017 - New Code 2018 2019 2020 2021 Billable/Specific Code
      • specified type NEC M04.8
    • Blau M04.8
    • Majeed M04.8
    • periodic fever, aphthous stomatitis, pharyngitis, and adenopathy [PFAPA] M04.8
    • pyogenic arthritis, pyoderma gangrenosum, and acne [PAPA] M04.8
    • Yao M04.8

ICD-10-CM Codes Adjacent To M04.8
M02.87 Other reactive arthropathies, ankle and foot
M02.871 Other reactive arthropathies, right ankle and foot
M02.872 Other reactive arthropathies, left ankle and foot
M02.879 Other reactive arthropathies, unspecified ankle and foot
M02.88 …… vertebrae
M02.89 …… multiple sites
M02.9 Reactive arthropathy, unspecified
M04 Autoinflammatory syndromes
M04.1 Periodic fever syndromes
M04.2 Cryopyrin-associated periodic syndromes
M04.8 Other autoinflammatory syndromes
M04.9 Autoinflammatory syndrome, unspecified
M05 Rheumatoid arthritis with rheumatoid factor
M05.0 Felty's syndrome
M05.00 …… unspecified site
M05.01 Felty's syndrome, shoulder
M05.011 Felty's syndrome, right shoulder
M05.012 Felty's syndrome, left shoulder
M05.019 Felty's syndrome, unspecified shoulder
M05.02 Felty's syndrome, elbow
M05.021 Felty's syndrome, right elbow

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.