2022 ICD-10-CM Diagnosis Code M31.11

Hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA]

    2022 - New Code Billable/Specific Code
  • M31.11 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • Short description: Hematpoetc stem cell txpltation-assoc throm microangiopathy
  • ICD-10-CM M31.11 is a new 2022 ICD-10-CM code that became effective on October 1, 2021.
  • This is the American ICD-10-CM version of M31.11 - other international versions of ICD-10 M31.11 may differ.
Applicable To
  • Transplant-associated thrombotic microangiopathy [TA-TMA]
Use Additional
Use Additional Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • code to identify specific organ dysfunction, such as:
  • acute kidney failure (
    ICD-10-CM Diagnosis Code N17
    • N17 Acute kidney failure
      • N17.0 Acute kidney failure with tubular necrosis
      • N17.1 Acute kidney failure with acute cortical necr...
      • N17.2 Acute kidney failure with medullary necrosis
      • N17.8 Other acute kidney failure
      • N17.9 Acute kidney failure, unspecified
    N17.-
    )
  • acute respiratory distress syndrome (
    ICD-10-CM Diagnosis Code J80

    Acute respiratory distress syndrome

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    Applicable To
    • Acute respiratory distress syndrome in adult or child
    • Adult hyaline membrane disease
    Type 1 Excludes
    • respiratory distress syndrome in newborn (perinatal) (P22.0)
    J80
    )
  • capillary leak syndrome (
    ICD-10-CM Diagnosis Code I78.8

    Other diseases of capillaries

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    I78.8
    )
  • diffuse alveolar hemorrhage (
    ICD-10-CM Diagnosis Code R04.89

    Hemorrhage from other sites in respiratory passages

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    Applicable To
    • Pulmonary hemorrhage NOS
    R04.89
    )
  • encephalopathy (metabolic) (septic) (
    ICD-10-CM Diagnosis Code G93.41

    Metabolic encephalopathy

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    Applicable To
    • Septic encephalopathy
    G93.41
    )
  • fluid overload, unspecified (
    ICD-10-CM Diagnosis Code E87.70

    Fluid overload, unspecified

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    E87.70
    )
  • graft versus host disease (
    ICD-10-CM Diagnosis Code D89.81

    Graft-versus-host disease

      2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
    Code First
    • underlying cause, such as:
    • complications of transplanted organs and tissue (T86.-)
    • complications of blood transfusion (T80.89)
    Use Additional
    • code to identify associated manifestations, such as:
    • desquamative dermatitis (L30.8)
    • diarrhea (R19.7)
    • elevated bilirubin (R17)
    • hair loss (L65.9)
    D89.81-
    )
  • hemolytic uremic syndrome (
    ICD-10-CM Diagnosis Code D59.3

    Hemolytic-uremic syndrome

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    Use Additional
    • code to identify associated:
    • E. coli infection (B96.2-)
    • Pneumococcal pneumonia (J13)
    • Shigella dysenteriae (A03.9)
    D59.3
    )
  • hepatic failure (
    ICD-10-CM Diagnosis Code K72
    • K72 Hepatic failure, not elsewhere classified
      • K72.0 Acute and subacute hepatic failure
        • K72.00 Acute and subacute hepatic failure without co...
        • K72.01 …… with coma
      • K72.1 Chronic hepatic failure
      • K72.9 Hepatic failure, unspecified
    K72.-
    )
  • hepatic veno-occlusive disease (
    ICD-10-CM Diagnosis Code K76.5

    Hepatic veno-occlusive disease

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    Type 1 Excludes
    • Budd-Chiari syndrome (I82.0)
    K76.5
    )
  • idiopathic interstitial pneumonia (
    ICD-10-CM Diagnosis Code J84.11

    Idiopathic interstitial pneumonia

      2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • lymphoid interstitial pneumonia (J84.2)
    • pneumocystis pneumonia (B59)
    J84.11-
    )
  • sinusoidal obstruction syndrome (
    ICD-10-CM Diagnosis Code K76.5

    Hepatic veno-occlusive disease

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    Type 1 Excludes
    • Budd-Chiari syndrome (I82.0)
    K76.5
    )
Code First
Code First Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • if applicable:
  • complications of bone marrow transplant (
    ICD-10-CM Diagnosis Code T86.0

    Complications of bone marrow transplant

      2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
    T86.0-
    )
  • complications of stem cell transplant (
    ICD-10-CM Diagnosis Code T86.5

    Complications of stem cell transplant

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    Applicable To
    • Complications from stem cells from peripheral blood
    • Complications from stem cells from umbilical cord
    T86.5
    )
The following code(s) above M31.11 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to M31.11:
  • M00-M99
    2022 ICD-10-CM Range M00-M99

    Diseases of the musculoskeletal system and connective tissue

    Note
    • Use an external cause code following the code for the musculoskeletal condition, if applicable, to identify the cause of the musculoskeletal condition
    Type 2 Excludes
    • arthropathic psoriasis (L40.5-)
    • certain conditions originating in the perinatal period (P04-P96)
    • certain infectious and parasitic diseases (A00-B99)
    • compartment syndrome (traumatic) (T79.A-)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the musculoskeletal system and connective tissue
  • M30-M36
    2022 ICD-10-CM Range M30-M36

    Systemic connective tissue disorders

    Includes
    • autoimmune disease NOS
    • collagen (vascular) disease NOS
    • systemic autoimmune disease
    • systemic collagen (vascular) disease
    Type 1 Excludes
    • autoimmune disease, single organ or single cell-type -code to relevant condition category
    Systemic connective tissue disorders
ICD-10-CM M31.11 is grouped within Diagnostic Related Group(s) (MS-DRG v39.0):
  • 545 Connective tissue disorders with mcc
  • 546 Connective tissue disorders with cc
  • 547 Connective tissue disorders without cc/mcc
Code History
  • 2022 (effective 10/1/2021): New code

Diagnosis Index entries containing back-references to M31.11:
  • HSCT-TMA M31.11 (hematopoietic stem cell transplantation-associated thrombotic microangiopathy)

ICD-10-CM Codes Adjacent To M31.11
M30 Polyarteritis nodosa and related conditions
M30.0 Polyarteritis nodosa
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
M30.2 Juvenile polyarteritis
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
M30.8 Other conditions related to polyarteritis nodosa
M31 Other necrotizing vasculopathies
M31.0 Hypersensitivity angiitis
M31.1 Thrombotic microangiopathy
M31.10 …… unspecified
M31.11 Hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA]
M31.19 Other thrombotic microangiopathy
M31.2 Lethal midline granuloma
M31.3 Wegener's granulomatosis
M31.30 …… without renal involvement
M31.31 …… with renal involvement
M31.4 Aortic arch syndrome [Takayasu]
M31.5 Giant cell arteritis with polymyalgia rheumatica
M31.6 Other giant cell arteritis
M31.7 Microscopic polyangiitis
M31.8 Other specified necrotizing vasculopathies

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.