2023 ICD-10-CM Diagnosis Code N12

Tubulo-interstitial nephritis, not specified as acute or chronic

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • N12 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • Short description: Tubulo-interstitial nephritis, not spcf as acute or chronic
  • The 2023 edition of ICD-10-CM N12 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of N12 - other international versions of ICD-10 N12 may differ.
Applicable To
  • Interstitial nephritis NOS
  • Pyelitis NOS
  • Pyelonephritis NOS
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as N12. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • calculous pyelonephritis (
    ICD-10-CM Diagnosis Code N20.9

    Urinary calculus, unspecified

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
The following code(s) above N12 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to N12:
  • N00-N99
    2023 ICD-10-CM Range N00-N99

    Diseases of the genitourinary system

    Type 2 Excludes
    • certain conditions originating in the perinatal period (P04-P96)
    • certain infectious and parasitic diseases (A00-B99)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the genitourinary system
  • N10-N16
    2023 ICD-10-CM Range N10-N16

    Renal tubulo-interstitial diseases

    • pyelonephritis
    Type 1 Excludes
    • pyeloureteritis cystica (N28.85)
    Renal tubulo-interstitial diseases
Approximate Synonyms
  • Drug-induced interstitial nephritis
  • Interstitial nephritis
  • Nephritis, interstitial, drug induced
  • Nephritis, tubulo-interstitial, primary/idiopathic
  • Nephritis, tubulo-interstitial, secondary
  • Obstructive pyelonephritis
  • Primary tubulointerstitial nephritis
  • Pyelonephritis
  • Pyelonephritis (kidney infection)
  • Secondary tubulointerstitial nephritis
Clinical Information
  • A disorder characterized by an infectious process involving the kidney.
  • An acute or chronic inflammatory process affecting the kidney. It is caused by bacteria and in most cases it is the result of a urinary tract infection. Signs and symptoms include fever, chills, flank pain, painful and frequent urination, cloudy or bloody urine, and confusion.
  • Diffuse or local inflammation and edema of the interstitial tissue of the kidney, including the tubules.
  • Inflammation of the interstitial tissue of the kidney. This term is generally used for primary inflammation of kidney tubules and/or surrounding interstitium. For primary inflammation of glomerular interstitium, see glomerulonephritis. Infiltration of the inflammatory cells into the interstitial compartment results in edema, increased spaces between the tubules, and tubular renal dysfunction.
  • Inflammation of the kidney and its pelvis due to infection.
  • Inflammation of the kidney involving the renal parenchyma (the nephrons); kidney pelvis; and kidney calices. It is characterized by abdominal pain; fever; nausea; vomiting; and occasionally diarrhea.
  • Inflammation of the kidney pelvis and kidney calices where urine is collected before discharge, but does not involve the renal parenchyma (the nephrons) where urine is processed.
ICD-10-CM N12 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 689 Kidney and urinary tract infections with mcc
  • 690 Kidney and urinary tract infections without mcc
  • 791 Prematurity with major problems
  • 793 Full term neonate with major problems

Convert N12 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
Code annotations containing back-references to N12:
  • Type 1 Excludes: N05
    ICD-10-CM Diagnosis Code N05

    Unspecified nephritic syndrome

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    • glomerular disease NOS
    • glomerulonephritis NOS
    • nephritis NOS
    • nephropathy NOS and renal disease NOS with morphological lesion specified in .0-.8
    Type 1 Excludes
    • nephropathy NOS with no stated morphological lesion (N28.9)
    • renal disease NOS with no stated morphological lesion (N28.9)
    • tubulo-interstitial nephritis NOS (N12)

Diagnosis Index entries containing back-references to N12:
  • Disease, diseased - see also Syndrome
    • antiglomerular basement membrane (anti- GBM) M31.0
      ICD-10-CM Diagnosis Code M31.0

      Hypersensitivity angiitis

        2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
      Applicable To
      • Goodpasture's syndrome
      • tubulo-interstitial nephritis N12
    • renal (functional) (pelvis) N28.9
      - see also Disease, kidney
      ICD-10-CM Diagnosis Code N28.9

      Disorder of kidney and ureter, unspecified

        2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
      Applicable To
      • Nephropathy NOS
      • Renal disease (acute) NOS
      • Renal insufficiency (acute)
      Type 1 Excludes
      • chronic renal insufficiency (N18.9)
      • unspecified nephritic syndrome (N05.-)
      • with
        • interstitial nephritis N12
  • Nephritis, nephritic (albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic) N05.9
    ICD-10-CM Diagnosis Code N05.9

    Unspecified nephritic syndrome with unspecified morphologic changes

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • Pyelonephritis - see also Nephritis, tubulo-interstitial
  • Pyonephritis N12

ICD-10-CM Codes Adjacent To N12
N07.8 Hereditary nephropathy, not elsewhere classified with other morphologic lesions
N07.9 Hereditary nephropathy, not elsewhere classified with unspecified morphologic lesions
N07.A Hereditary nephropathy, not elsewhere classified with C3 glomerulonephritis
N08 Glomerular disorders in diseases classified elsewhere
N10 Acute pyelonephritis
N11 Chronic tubulo-interstitial nephritis
N11.0 Nonobstructive reflux-associated chronic pyelonephritis
N11.1 Chronic obstructive pyelonephritis
N11.8 Other chronic tubulo-interstitial nephritis
N11.9 Chronic tubulo-interstitial nephritis, unspecified
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
N13 Obstructive and reflux uropathy
N13.0 Hydronephrosis with ureteropelvic junction obstruction
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
N13.3 Other and unspecified hydronephrosis
N13.30 Unspecified hydronephrosis
N13.39 Other hydronephrosis
N13.4 Hydroureter
N13.5 Crossing vessel and stricture of ureter without hydronephrosis
N13.6 Pyonephrosis

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.