2020 ICD-10-CM Diagnosis Code N25.1

Nephrogenic diabetes insipidus

    2016 2017 2018 2019 2020 Billable/Specific Code
  • N25.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2020 edition of ICD-10-CM N25.1 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of N25.1 - other international versions of ICD-10 N25.1 may differ.
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as N25.1. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • diabetes insipidus NOS (
    ICD-10-CM Diagnosis Code E23.2

    Diabetes insipidus

      2016 2017 2018 2019 2020 Billable/Specific Code
    Type 1 Excludes
    • nephrogenic diabetes insipidus (N25.1)
    E23.2
    )
The following code(s) above N25.1 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to N25.1:
  • N00-N99
    2020 ICD-10-CM Range N00-N99

    Diseases of the genitourinary system

    Type 2 Excludes
    • certain conditions originating in the perinatal period (P04-P96)
    • certain infectious and parasitic diseases (A00-B99)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the genitourinary system
  • N25-N29
    2020 ICD-10-CM Range N25-N29

    Other disorders of kidney and ureter

    Type 2 Excludes
    • disorders of kidney and ureter with urolithiasis (N20-N23)
    Other disorders of kidney and ureter
Approximate Synonyms
  • Partial nephrogenic diabetes insipidus
Clinical Information
  • A genetic or acquired polyuric disorder characterized by persistent hypotonic urine and hypokalemia. This condition is due to renal tubular insensitivity to vasopressin and failure to reduce urine volume. It may be the result of mutations of genes encoding vasopressin receptors or aquaporin-2 (aquaporins); kidney diseases; adverse drug effects; or complications from pregnancy.
  • Diabetes insipidus caused by insensitivity of the kidneys to antidiuretic hormone.
  • Polyuric disorder characterized by normal rates of renal filtration and solute excretion, but a persistent hypotonic urine due to the failure of renal tubules to respond to antidiuretic hormones, such as vasopressin, to reduce urine volume; tubular insensitivity to vasopressin can result from genetic defects, diseases, drug effects, or may occur with pregnancy.
ICD-10-CM N25.1 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0):
  • 698 Other kidney and urinary tract diagnoses with mcc
  • 699 Other kidney and urinary tract diagnoses with cc
  • 700 Other kidney and urinary tract diagnoses without cc/mcc

Convert N25.1 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
Code annotations containing back-references to N25.1:
  • Type 1 Excludes: E23.2
    ICD-10-CM Diagnosis Code E23.2

    Diabetes insipidus

      2016 2017 2018 2019 2020 Billable/Specific Code
    Type 1 Excludes
    • nephrogenic diabetes insipidus (N25.1)

Diagnosis Index entries containing back-references to N25.1:
  • Diabetes, diabetic (mellitus) (sugar) E11.9
    ICD-10-CM Diagnosis Code E11.9

    Type 2 diabetes mellitus without complications

      2016 2017 2018 2019 2020 Billable/Specific Code Questionable As Admission Dx
    • insipidus E23.2
      ICD-10-CM Diagnosis Code E23.2

      Diabetes insipidus

        2016 2017 2018 2019 2020 Billable/Specific Code
      Type 1 Excludes
      • nephrogenic diabetes insipidus (N25.1)
      • nephrogenic N25.1
      • vasopressin resistant N25.1

ICD-10-CM Codes Adjacent To N25.1
N20.9 Urinary calculus, unspecified
N21 Calculus of lower urinary tract
N21.0 Calculus in bladder
N21.1 Calculus in urethra
N21.8 Other lower urinary tract calculus
N21.9 Calculus of lower urinary tract, unspecified
N22 Calculus of urinary tract in diseases classified elsewhere
N23 Unspecified renal colic
N25 Disorders resulting from impaired renal tubular function
N25.0 Renal osteodystrophy
N25.1 Nephrogenic diabetes insipidus
N25.8 Other disorders resulting from impaired renal tubular function
N25.81 Secondary hyperparathyroidism of renal origin
N25.89 Other disorders resulting from impaired renal tubular function
N25.9 Disorder resulting from impaired renal tubular function, unspecified
N26 Unspecified contracted kidney
N26.1 Atrophy of kidney (terminal)
N26.2 Page kidney
N26.9 Renal sclerosis, unspecified
N27 Small kidney of unknown cause
N27.0 Small kidney, unilateral

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.