2021 ICD-10-CM Diagnosis Code N25.81

Secondary hyperparathyroidism of renal origin

    2016 2017 2018 2019 2020 2021 Billable/Specific Code
  • N25.81 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2021 edition of ICD-10-CM N25.81 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of N25.81 - other international versions of ICD-10 N25.81 may differ.
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as N25.81. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • secondary hyperparathyroidism, non-renal (
    ICD-10-CM Diagnosis Code E21.1

    Secondary hyperparathyroidism, not elsewhere classified

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Type 1 Excludes
    • secondary hyperparathyroidism of renal origin (N25.81)
    E21.1
    )
Type 2 Excludes
Type 2 Excludes Help
A type 2 excludes note represents "not included here". A type 2 excludes note indicates that the condition excluded is not part of the condition it is excluded from but a patient may have both conditions at the same time. When a type 2 excludes note appears under a code it is acceptable to use both the code (N25.81) and the excluded code together.
  • metabolic disorders classifiable to E70-E88
    ICD-10-CM Range E70-E88

    Metabolic disorders

    Type 1 Excludes
    • androgen insensitivity syndrome (E34.5-)
    • congenital adrenal hyperplasia (E25.0)
    • Ehlers-Danlos syndromes (Q79.6-)
    • hemolytic anemias attributable to enzyme disorders (D55.-)
    • Marfan's syndrome (Q87.4)
    • 5-alpha-reductase deficiency (E29.1)
    • E70 Disorders of aromatic amino-acid metabol...
    • E71 Disorders of branched-chain amino-acid m...
    • E72 Other disorders of amino-acid metabolism
    • E73 Lactose intolerance
    • E74 Other disorders of carbohydrate metaboli...
    • E75 Disorders of sphingolipid metabolism and...
    • E76 Disorders of glycosaminoglycan metabolis...
    • E77 Disorders of glycoprotein metabolism
    • E78 Disorders of lipoprotein metabolism and ...
    • E79 Disorders of purine and pyrimidine metab...
    • E80 Disorders of porphyrin and bilirubin met...
    • E83 Disorders of mineral metabolism
    • E84 Cystic fibrosis
    • E85 Amyloidosis
    • E86 Volume depletion
    • E87 Other disorders of fluid, electrolyte an...
    • E88 Other and unspecified metabolic disorder...
The following code(s) above N25.81 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to N25.81:
  • N00-N99
    2021 ICD-10-CM Range N00-N99

    Diseases of the genitourinary system

    Type 2 Excludes
    • certain conditions originating in the perinatal period (P04-P96)
    • certain infectious and parasitic diseases (A00-B99)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the genitourinary system
  • N25-N29
    2021 ICD-10-CM Range N25-N29

    Other disorders of kidney and ureter

    Type 2 Excludes
    • disorders of kidney and ureter with urolithiasis (N20-N23)
    Other disorders of kidney and ureter
Approximate Synonyms
  • Chronic kidney disease due to type 2 diabetes mellitus with hyperparathyroidism due to end stage renal disease on dialysis
  • Dm 2 w diabetic ckd, secondary hyperparathyroidism due to esrd, on dialysis
  • Hyperparathyroidism due to end stage renal disease on dialysis
  • Hyperparathyroidism due to renal insufficiency
  • Hyperparathyroidism, secondary
  • Secondary hyperparathyroidism
  • Secondary hyperparathyroidism due to esrd, on dialysis
ICD-10-CM N25.81 is grouped within Diagnostic Related Group(s) (MS-DRG v38.0):
  • 698 Other kidney and urinary tract diagnoses with mcc
  • 699 Other kidney and urinary tract diagnoses with cc
  • 700 Other kidney and urinary tract diagnoses without cc/mcc

Convert N25.81 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
Code annotations containing back-references to N25.81:
  • Type 1 Excludes: E21.1
    ICD-10-CM Diagnosis Code E21.1

    Secondary hyperparathyroidism, not elsewhere classified

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Type 1 Excludes
    • secondary hyperparathyroidism of renal origin (N25.81)

Diagnosis Index entries containing back-references to N25.81:
  • Hyperparathyroidism E21.3
    ICD-10-CM Diagnosis Code E21.3

    Hyperparathyroidism, unspecified

      2016 2017 2018 2019 2020 2021 Billable/Specific Code

ICD-10-CM Codes Adjacent To N25.81
N21.0 Calculus in bladder
N21.1 Calculus in urethra
N21.8 Other lower urinary tract calculus
N21.9 Calculus of lower urinary tract, unspecified
N22 Calculus of urinary tract in diseases classified elsewhere
N23 Unspecified renal colic
N25 Disorders resulting from impaired renal tubular function
N25.0 Renal osteodystrophy
N25.1 Nephrogenic diabetes insipidus
N25.8 Other disorders resulting from impaired renal tubular function
N25.81 Secondary hyperparathyroidism of renal origin
N25.89 Other disorders resulting from impaired renal tubular function
N25.9 Disorder resulting from impaired renal tubular function, unspecified
N26 Unspecified contracted kidney
N26.1 Atrophy of kidney (terminal)
N26.2 Page kidney
N26.9 Renal sclerosis, unspecified
N27 Small kidney of unknown cause
N27.0 Small kidney, unilateral
N27.1 Small kidney, bilateral
N27.9 Small kidney, unspecified

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.