2022 ICD-10-CM Diagnosis Code O01.9

Hydatidiform mole, unspecified

    2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code Maternity Dx (12-55 years)
  • O01.9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2022 edition of ICD-10-CM O01.9 became effective on October 1, 2021.
  • This is the American ICD-10-CM version of O01.9 - other international versions of ICD-10 O01.9 may differ.
ICD-10-CM Coding Rules
  • O01.9 is applicable to maternity patients aged 12 - 55 years inclusive.
Applicable To
  • Trophoblastic disease NOS
  • Vesicular mole NOS
The following code(s) above O01.9 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to O01.9:
  • O00-O9A
    2022 ICD-10-CM Range O00-O9A

    Pregnancy, childbirth and the puerperium

    Note
    • CODES FROM THIS CHAPTER ARE FOR USE ONLY ON MATERNAL RECORDS, NEVER ON NEWBORN RECORDS
    • Codes from this chapter are for use for conditions related to or aggravated by the pregnancy, childbirth, or by the puerperium (maternal causes or obstetric causes)
    • Trimesters are counted from the first day of the last menstrual period. They are defined as follows:
    • 1st trimester- less than 14 weeks 0 days
    • 2nd trimester- 14 weeks 0 days to less than 28 weeks 0 days
    • 3rd trimester- 28 weeks 0 days until delivery
    Type 1 Excludes
    • supervision of normal pregnancy (Z34.-)
    Type 2 Excludes
    • mental and behavioral disorders associated with the puerperium (F53.-)
    • obstetrical tetanus (A34)
    • postpartum necrosis of pituitary gland (E23.0)
    • puerperal osteomalacia (M83.0)
    Use Additional
    • code from category Z3A, Weeks of gestation, to identify the specific week of the pregnancy, if known.
    Pregnancy, childbirth and the puerperium
  • O00-O08
    2022 ICD-10-CM Range O00-O08

    Pregnancy with abortive outcome

    Type 1 Excludes
    • continuing pregnancy in multiple gestation after abortion of one fetus or more (O31.1-, O31.3-)
    Pregnancy with abortive outcome
  • O01
    ICD-10-CM Diagnosis Code O01

    Hydatidiform mole

      2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • chorioadenoma (destruens) (D39.2)
    • malignant hydatidiform mole (D39.2)
    Use Additional
    • code from category O08 to identify any associated complication.
    Hydatidiform mole
Approximate Synonyms
  • Gestational trophoblastic disease
Clinical Information
  • A gestational disorder characterized by an abnormal placenta with marked enlargement of the chorionic villi and hyperplasia of the villous trophoblastic cells. According to the amount of villous involvement, a hydatidiform mole is defined as complete or partial. Most molar pregnancies are complete and are characterized by generalized hydropic villous changes. Partial moles are characterized by a mixture of large hydropic villi and normal placenta tissue. Complete moles are usually diploid and typically present between the eleventh and twenty-fifth week of pregnancy, whereas partial moles are usually triploid and usually present around the nineteenth week of pregnancy. The incidence of choriocarcinoma is higher in patients with complete hydatidiform mole. When a hydatidiform mole invades the myometrium and broad ligament, or it is found in distant sites as vagina, vulva, and lung, it is referred as invasive mole.
  • A group of diseases arising from pregnancy that are commonly associated with hyperplasia of trophoblasts (trophoblast) and markedly elevated human chorionic gonadotropin. They include hydatidiform mole, invasive mole (hydatidiform mole, invasive), placental-site trophoblastic tumor (trophoblastic tumor, placental site), and choriocarcinoma. These neoplasms have varying propensities for invasion and spread.
  • A rare cancer in women of childbearing age in which cancer cells grow in the tissues that are formed in the uterus after conception. Also called gestational trophoblastic disease, gestational trophoblastic neoplasia, gestational trophoblastic tumor, or choriocarcinoma.
  • A slow-growing tumor that develops from trophoblastic cells (cells that help an embryo attach to the uterus and help form the placenta) after fertilization of an egg by a sperm. A hydatidiform mole contains many cysts (sacs of fluid). It is usually benign (not cancer) but it may spread to nearby tissues (invasive mole). It may also become a malignant tumor called choriocarcinoma. Hydatidiform mole is the most common type of gestational trophoblastic tumor.
  • Derived from the fertilization of an anuclear ovum by one or sometimes two haploid sperm. Its molar chromosomes derive entirely from the paternal origin. It has no identifiable embryonic or fetal tissue. The chorionic villi have generalized swelling and diffuse trophoblastic hyperplasia. Most complete moles (>90%) have a 46,xx karyotype and the rest 46,xy karyotype.
  • Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the chorionic villi and elevated human chorionic gonadotropin. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.
  • Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy; characterized by the swelling of the chorionic villi and elevated human chorionic gonadotropin; hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.
ICD-10-CM O01.9 is grouped within Diagnostic Related Group(s) (MS-DRG v39.0):
  • 817 Other antepartum diagnoses with o.r. Procedures with mcc
  • 818 Other antepartum diagnoses with o.r. Procedures with cc
  • 819 Other antepartum diagnoses with o.r. Procedures without cc/mcc
  • 831 Other antepartum diagnoses without o.r. Procedures with mcc
  • 832 Other antepartum diagnoses without o.r. Procedures with cc
  • 833 Other antepartum diagnoses without o.r. Procedures without cc/mcc

Convert O01.9 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
Code annotations containing back-references to O01.9:
  • Type 1 Excludes: C58
    , D39.2
    ICD-10-CM Diagnosis Code C58

    Malignant neoplasm of placenta

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code Maternity Dx (12-55 years) Female Dx
    Includes
    • choriocarcinoma NOS
    • chorionepithelioma NOS
    Type 1 Excludes
    • chorioadenoma (destruens) (D39.2)
    • hydatidiform mole NOS (O01.9)
    • invasive hydatidiform mole (D39.2)
    • male choriocarcinoma NOS (C62.9-)
    • malignant hydatidiform mole (D39.2)
    ICD-10-CM Diagnosis Code D39.2

    Neoplasm of uncertain behavior of placenta

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code Maternity Dx (12-55 years)
    Applicable To
    • Chorioadenoma destruens
    • Invasive hydatidiform mole
    • Malignant hydatidiform mole
    Type 1 Excludes
    • hydatidiform mole NOS (O01.9)

Diagnosis Index entries containing back-references to O01.9:
  • Hydatidiform mole (benign) (complicating pregnancy) (delivered) (undelivered) O01.9
  • Mole (pigmented) - see also Nevus
  • Pregnancy (single) (uterine) Z33.1
    - see also Delivery and Puerperal
    ICD-10-CM Diagnosis Code Z33.1

    Pregnant state, incidental

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code Maternity Dx (12-55 years)
    Applicable To
    • Pregnancy NOS
    • Pregnant state NOS
    Type 1 Excludes
    • complications of pregnancy (O00-O9A)
    • pregnant state, gestational carrier (Z33.3)
    • complicated by (care of) (management affected by)
    • molar NEC O02.0
      ICD-10-CM Diagnosis Code O02.0

      Blighted ovum and nonhydatidiform mole

        2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code Maternity Dx (12-55 years)
      Applicable To
      • Carneous mole
      • Fleshy mole
      • Intrauterine mole NOS
      • Molar pregnancy NEC
      • Pathological ovum
  • Trophoblastic disease O01.9 - see also Mole, hydatidiform

ICD-10-CM Codes Adjacent To O01.9
O00.219 Unspecified ovarian pregnancy with intrauterine pregnancy
O00.8 Other ectopic pregnancy
O00.80 …… without intrauterine pregnancy
O00.81 …… with intrauterine pregnancy
O00.9 Ectopic pregnancy, unspecified
O00.90 Unspecified ectopic pregnancy without intrauterine pregnancy
O00.91 Unspecified ectopic pregnancy with intrauterine pregnancy
O01 Hydatidiform mole
O01.0 Classical hydatidiform mole
O01.1 Incomplete and partial hydatidiform mole
O01.9 Hydatidiform mole, unspecified
O02 Other abnormal products of conception
O02.0 Blighted ovum and nonhydatidiform mole
O02.1 Missed abortion
O02.8 Other specified abnormal products of conception
O02.81 Inappropriate change in quantitative human chorionic gonadotropin (hCG) in early pregnancy
O02.89 Other abnormal products of conception
O02.9 Abnormal product of conception, unspecified
O03 Spontaneous abortion
O03.0 Genital tract and pelvic infection following incomplete spontaneous abortion
O03.1 Delayed or excessive hemorrhage following incomplete spontaneous abortion

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.