ICD-10-CM Codes
O00-O9A
O20-O29
O21-
2023 ICD-10-CM Diagnosis Code O21

2023 ICD-10-CM Diagnosis Code O21

Excessive vomiting in pregnancy

2016

2017

2018

2019

2020

2021

2022

2023

Non-Billable/Non-Specific Code

O21 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
The 2023 edition of ICD-10-CM O21 became effective on October 1, 2022.
This is the American ICD-10-CM version of O21 - other international versions of ICD-10 O21 may differ.

The following code(s) above O21 contain annotation back-references

Annotation Back-References

In this context, annotation back-references refer to codes that contain:

Applicable To annotations, or
Code Also annotations, or
Code First annotations, or
Excludes1 annotations, or
Excludes2 annotations, or
Includes annotations, or
Note annotations, or
Use Additional annotations

that may be applicable to O21:

O00-O9A
2023 ICD-10-CM Range O00-O9A
Pregnancy, childbirth and the puerperium
Note
- CODES FROM THIS CHAPTER ARE FOR USE ONLY ON MATERNAL RECORDS, NEVER ON NEWBORN RECORDS
- Codes from this chapter are for use for conditions related to or aggravated by the pregnancy, childbirth, or by the puerperium (maternal causes or obstetric causes)
- Trimesters are counted from the first day of the last menstrual period. They are defined as follows:
- 1st trimester- less than 14 weeks 0 days
- 2nd trimester- 14 weeks 0 days to less than 28 weeks 0 days
- 3rd trimester- 28 weeks 0 days until delivery
Type 1 Excludes
- supervision of normal pregnancy (Z34.-)
Type 2 Excludes
- mental and behavioral disorders associated with the puerperium (F53.-)
- obstetrical tetanus (A34)
- postpartum necrosis of pituitary gland (E23.0)
- puerperal osteomalacia (M83.0)
Use Additional
- code from category Z3A, Weeks of gestation, to identify the specific week of the pregnancy, if known.
Pregnancy, childbirth and the puerperium
O20-O29
2023 ICD-10-CM Range O20-O29
Other maternal disorders predominantly related to pregnancy
Type 2 Excludes
- maternal care related to the fetus and amniotic cavity and possible delivery problems (O30-O48)
- maternal diseases classifiable elsewhere but complicating pregnancy, labor and delivery, and the puerperium (O98-O99)
Other maternal disorders predominantly related to pregnancy

Clinical Information

Intractable vomiting that develops in early pregnancy and persists. This can lead to dehydration and weight loss.
Severe, intractable vomiting during pregnancy (usually the first trimester) accompanied by dehydration, weight loss, and electrolyte imbalances.

Code History

2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
2017 (effective 10/1/2016): No change
2018 (effective 10/1/2017): No change
2019 (effective 10/1/2018): No change
2020 (effective 10/1/2019): No change
2021 (effective 10/1/2020): No change
2022 (effective 10/1/2021): No change
2023 (effective 10/1/2022): No change

Code annotations containing back-references to O21:

Type 1 Excludes: R11

ICD-10-CM Diagnosis Code R11
Nausea and vomiting
Type 1 Excludes
- cyclical vomiting associated with migraine (G43.A-)
- excessive vomiting in pregnancy (O21.-)
- hematemesis (K92.0)
- neonatal hematemesis (P54.0)
- newborn vomiting (P92.0-)
- psychogenic vomiting (F50.89)
- vomiting associated with bulimia nervosa (F50.2)
- vomiting following gastrointestinal surgery (K91.0)

ICD-10-CM Codes Adjacent To O21

O16.1 Unspecified maternal hypertension, first trimester

O16.2 Unspecified maternal hypertension, second trimester

O16.3 Unspecified maternal hypertension, third trimester

O16.4 Unspecified maternal hypertension, complicating childbirth

O16.5 Unspecified maternal hypertension, complicating the puerperium

O16.9 Unspecified maternal hypertension, unspecified trimester

O20 Hemorrhage in early pregnancy

O20.0 Threatened abortion

O20.8 Other hemorrhage in early pregnancy

O20.9 Hemorrhage in early pregnancy, unspecified

O21 Excessive vomiting in pregnancy

O21.0 Mild hyperemesis gravidarum

O21.1 Hyperemesis gravidarum with metabolic disturbance

O21.2 Late vomiting of pregnancy

O21.8 Other vomiting complicating pregnancy

O21.9 Vomiting of pregnancy, unspecified

O22 Venous complications and hemorrhoids in pregnancy

O22.0 Varicose veins of lower extremity in pregnancy

O22.00 …… unspecified trimester

O22.01 …… first trimester

O22.02 …… second trimester

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

2023 ICD-10-CM Diagnosis Code O21

Excessive vomiting in pregnancy

Pregnancy, childbirth and the puerperium

Other maternal disorders predominantly related to pregnancy

Nausea and vomiting