2020 ICD-10-CM Diagnosis Code O21.1

Hyperemesis gravidarum with metabolic disturbance

    2016 2017 2018 2019 2020 Billable/Specific Code Maternity Dx (12-55 years)
  • O21.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2020 edition of ICD-10-CM O21.1 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of O21.1 - other international versions of ICD-10 O21.1 may differ.
ICD-10-CM Coding Rules
  • O21.1 is applicable to maternity patients aged 12 - 55 years inclusive.
Applicable To
  • Hyperemesis gravidarum, starting before the end of the 20th week of gestation, with metabolic disturbance such as carbohydrate depletion
  • Hyperemesis gravidarum, starting before the end of the 20th week of gestation, with metabolic disturbance such as dehydration
  • Hyperemesis gravidarum, starting before the end of the 20th week of gestation, with metabolic disturbance such as electrolyte imbalance
The following code(s) above O21.1 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to O21.1:
  • O00-O9A
    2020 ICD-10-CM Range O00-O9A

    Pregnancy, childbirth and the puerperium

    Note
    • CODES FROM THIS CHAPTER ARE FOR USE ONLY ON MATERNAL RECORDS, NEVER ON NEWBORN RECORDS
    • Codes from this chapter are for use for conditions related to or aggravated by the pregnancy, childbirth, or by the puerperium (maternal causes or obstetric causes)
    • Trimesters are counted from the first day of the last menstrual period. They are defined as follows:
    • 1st trimester- less than 14 weeks 0 days
    • 2nd trimester- 14 weeks 0 days to less than 28 weeks 0 days
    • 3rd trimester- 28 weeks 0 days until delivery
    Type 1 Excludes
    • supervision of normal pregnancy (Z34.-)
    Type 2 Excludes
    • mental and behavioral disorders associated with the puerperium (F53.-)
    • obstetrical tetanus (A34)
    • postpartum necrosis of pituitary gland (E23.0)
    • puerperal osteomalacia (M83.0)
    Use Additional
    • code from category Z3A, Weeks of gestation, to identify the specific week of the pregnancy, if known.
    Pregnancy, childbirth and the puerperium
  • O20-O29
    2020 ICD-10-CM Range O20-O29

    Other maternal disorders predominantly related to pregnancy

    Type 2 Excludes
    • maternal care related to the fetus and amniotic cavity and possible delivery problems (O30-O48)
    • maternal diseases classifiable elsewhere but complicating pregnancy, labor and delivery, and the puerperium (O98-O99)
    Other maternal disorders predominantly related to pregnancy
Approximate Synonyms
  • Hyperemesis gravidarum (excessive vomiting in pregnancy), severe
  • Hyperemesis gravidarum (severe vomiting in pregnancy) with metabolic disturbance
  • Severe hyperemesis gravidarum
ICD-10-CM O21.1 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0):
  • 817 Other antepartum diagnoses with o.r. Procedure with mcc
  • 818 Other antepartum diagnoses with o.r. Procedure with cc
  • 819 Other antepartum diagnoses with o.r. Procedure without cc/mcc
  • 831 Other antepartum diagnoses without o.r. Procedure with mcc
  • 832 Other antepartum diagnoses without o.r. Procedure with cc
  • 833 Other antepartum diagnoses without o.r. Procedure without cc/mcc

Convert O21.1 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
Code annotations containing back-references to O21.1:
  • Type 1 Excludes: E87
    ICD-10-CM Diagnosis Code E87

    Other disorders of fluid, electrolyte and acid-base balance

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • diabetes insipidus (E23.2)
    • electrolyte imbalance associated with hyperemesis gravidarum (O21.1)
    • electrolyte imbalance following ectopic or molar pregnancy (O08.5)
    • familial periodic paralysis (G72.3)

Diagnosis Index entries containing back-references to O21.1:
  • Hyperemesis R11.10
    ICD-10-CM Diagnosis Code R11.10

    Vomiting, unspecified

      2016 2017 2018 2019 2020 Billable/Specific Code
    Applicable To
    • Vomiting NOS
    • gravidarum (mild) O21.0
      ICD-10-CM Diagnosis Code O21.0

      Mild hyperemesis gravidarum

        2016 2017 2018 2019 2020 Billable/Specific Code Maternity Dx (12-55 years)
      Applicable To
      • Hyperemesis gravidarum, mild or unspecified, starting before the end of the 20th week of gestation
      • with
        • carbohydrate depletion O21.1
        • dehydration O21.1
        • electrolyte imbalance O21.1
        • metabolic disturbance O21.1
      • severe O21.1 (with metabolic disturbance)
  • Imbalance R26.89
    ICD-10-CM Diagnosis Code R26.89

    Other abnormalities of gait and mobility

      2016 2017 2018 2019 2020 Billable/Specific Code
    • electrolyte E87.8
      ICD-10-CM Diagnosis Code E87.8

      Other disorders of electrolyte and fluid balance, not elsewhere classified

        2016 2017 2018 2019 2020 Billable/Specific Code
      Applicable To
      • Electrolyte imbalance NOS
      • Hyperchloremia
      • Hypochloremia
      • due to hyperemesis gravidarum O21.1

ICD-10-CM Codes Adjacent To O21.1
O16.3 Unspecified maternal hypertension, third trimester
O16.4 Unspecified maternal hypertension, complicating childbirth
O16.5 Unspecified maternal hypertension, complicating the puerperium
O16.9 Unspecified maternal hypertension, unspecified trimester
O20 Hemorrhage in early pregnancy
O20.0 Threatened abortion
O20.8 Other hemorrhage in early pregnancy
O20.9 Hemorrhage in early pregnancy, unspecified
O21 Excessive vomiting in pregnancy
O21.0 Mild hyperemesis gravidarum
O21.1 Hyperemesis gravidarum with metabolic disturbance
O21.2 Late vomiting of pregnancy
O21.8 Other vomiting complicating pregnancy
O21.9 Vomiting of pregnancy, unspecified
O22 Venous complications and hemorrhoids in pregnancy
O22.0 Varicose veins of lower extremity in pregnancy
O22.00 …… unspecified trimester
O22.01 …… first trimester
O22.02 …… second trimester
O22.03 …… third trimester
O22.1 Genital varices in pregnancy

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.