1. ICD-10-CM Codes
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2. P00-P96 Certain conditions originating in the perinatal period
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3. P50-P61 Hemorrhagic and hematological disorders of newborn
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4. P55- Hemolytic disease of newborn
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5. 2021 ICD-10-CM Diagnosis Code P55

2021 ICD-10-CM Diagnosis Code P55

Hemolytic disease of newborn

2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code

• P55 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
• The 2021 edition of ICD-10-CM P55 became effective on October 1, 2020.
• This is the American ICD-10-CM version of P55 - other international versions of ICD-10 P55 may differ.

• A condition characterized by the abnormal presence of erythroblasts in the circulation of the fetus or newborns. It is a disorder due to blood group incompatibility, such as the maternal alloimmunization by fetal antigen rh factors leading to hemolysis of erythrocytes, hemolytic anemia (anemia, hemolytic), general edema (hydrops fetalis), and severe jaundice in newborn.
• Hemolytic anemia of the fetus or newborn caused by transplacental transmission of maternally formed antibody, usually secondary to an incompatibility between the blood groups of mother and offspring.

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change
• 2021 (effective 10/1/2020): No change

• Type 1 Excludes: D58
  , R17
  , R71
  , R76.0
  ICD-10-CM Diagnosis Code D58

  Other hereditary hemolytic anemias

  2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code

  Type 1 Excludes

  • hemolytic anemia of the newborn (P55.-)
  ICD-10-CM Diagnosis Code R17

  Unspecified jaundice

  2016 2017 2018 2019 2020 2021 Billable/Specific Code

  Type 1 Excludes

  • neonatal jaundice (P55, P57-P59)
  ICD-10-CM Diagnosis Code R71

  Abnormality of red blood cells

  2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code

  Type 1 Excludes

  • anemias (D50-D64)
  • anemia of premature infant (P61.2)
  • benign (familial) polycythemia (D75.0)
  • congenital anemias (P61.2-P61.4)
  • newborn anemia due to isoimmunization (P55.-)
  • polycythemia neonatorum (P61.1)
  • polycythemia NOS (D75.1)
  • polycythemia vera (D45)
  • secondary polycythemia (D75.1)
  ICD-10-CM Diagnosis Code R76.0

  Raised antibody titer

  2016 2017 2018 2019 2020 2021 Billable/Specific Code

  Type 1 Excludes

  • isoimmunization in pregnancy (O36.0-O36.1)
  • isoimmunization affecting newborn (P55.-)
• Type 2 Excludes: D59.1
  ICD-10-CM Diagnosis Code D59.1

  Other autoimmune hemolytic anemias

  2016 2017 2018 2019 2020 2021 - Converted to Parent Code Non-Billable/Non-Specific Code

  Type 2 Excludes

  • Evans syndrome (D69.41)
  • hemolytic disease of newborn (P55.-)
  • paroxysmal cold hemoglobinuria (D59.6)

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.