2020 ICD-10-CM Diagnosis Code P55

Hemolytic disease of newborn

    2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
  • P55 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2020 edition of ICD-10-CM P55 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of P55 - other international versions of ICD-10 P55 may differ.
The following code(s) above P55 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to P55:
  • P00-P96
    2020 ICD-10-CM Range P00-P96

    Certain conditions originating in the perinatal period

    Includes
    • conditions that have their origin in the fetal or perinatal period (before birth through the first 28 days after birth) even if morbidity occurs later
    Note
    • Codes from this chapter are for use on newborn records only, never on maternal records
    Type 2 Excludes
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • tetanus neonatorum (A33)
    Certain conditions originating in the perinatal period
  • P50-P61
    2020 ICD-10-CM Range P50-P61

    Hemorrhagic and hematological disorders of newborn

    Type 1 Excludes
    • congenital stenosis and stricture of bile ducts (Q44.3)
    • Crigler-Najjar syndrome (E80.5)
    • Dubin-Johnson syndrome (E80.6)
    • Gilbert syndrome (E80.4)
    • hereditary hemolytic anemias (D55-D58)
    Hemorrhagic and hematological disorders of newborn
Clinical Information
  • A condition characterized by the abnormal presence of erythroblasts in the circulation of the fetus or newborns. It is a disorder due to blood group incompatibility, such as the maternal alloimmunization by fetal antigen rh factors leading to hemolysis of erythrocytes, hemolytic anemia (anemia, hemolytic), general edema (hydrops fetalis), and severe jaundice in newborn.
  • Hemolytic anemia of the fetus or newborn caused by transplacental transmission of maternally formed antibody, usually secondary to an incompatibility between the blood groups of mother and offspring.
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
Code annotations containing back-references to P55:
  • Type 1 Excludes: D58
    , D59.1
    , R17
    , R76.0
    , R71
    ICD-10-CM Diagnosis Code D58

    Other hereditary hemolytic anemias

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • hemolytic anemia of the newborn (P55.-)
    ICD-10-CM Diagnosis Code D59.1

    Other autoimmune hemolytic anemias

      2016 2017 2018 2019 2020 Billable/Specific Code
    Applicable To
    • Autoimmune hemolytic disease (cold type) (warm type)
    • Chronic cold hemagglutinin disease
    • Cold agglutinin disease
    • Cold agglutinin hemoglobinuria
    • Cold type (secondary) (symptomatic) hemolytic anemia
    • Warm type (secondary) (symptomatic) hemolytic anemia
    Type 1 Excludes
    • Evans syndrome (D69.41)
    • hemolytic disease of newborn (P55.-)
    • paroxysmal cold hemoglobinuria (D59.6)
    ICD-10-CM Diagnosis Code R17

    Unspecified jaundice

      2016 2017 2018 2019 2020 Billable/Specific Code
    Type 1 Excludes
    ICD-10-CM Diagnosis Code R76.0

    Raised antibody titer

      2016 2017 2018 2019 2020 Billable/Specific Code
    Type 1 Excludes
    • isoimmunization in pregnancy (O36.0-O36.1)
    • isoimmunization affecting newborn (P55.-)
    ICD-10-CM Diagnosis Code R71

    Abnormality of red blood cells

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • anemias (D50-D64)
    • anemia of premature infant (P61.2)
    • benign (familial) polycythemia (D75.0)
    • congenital anemias (P61.2-P61.4)
    • newborn anemia due to isoimmunization (P55.-)
    • polycythemia neonatorum (P61.1)
    • polycythemia NOS (D75.1)
    • polycythemia vera (D45)
    • secondary polycythemia (D75.1)
ICD-10-CM Codes Adjacent To P55
P54 Other neonatal hemorrhages
P54.0 Neonatal hematemesis
P54.1 Neonatal melena
P54.2 Neonatal rectal hemorrhage
P54.3 Other neonatal gastrointestinal hemorrhage
P54.4 Neonatal adrenal hemorrhage
P54.5 Neonatal cutaneous hemorrhage
P54.6 Neonatal vaginal hemorrhage
P54.8 Other specified neonatal hemorrhages
P54.9 Neonatal hemorrhage, unspecified
P55 Hemolytic disease of newborn
P55.0 Rh isoimmunization of newborn
P55.1 ABO isoimmunization of newborn
P55.8 Other hemolytic diseases of newborn
P55.9 Hemolytic disease of newborn, unspecified
P56 Hydrops fetalis due to hemolytic disease
P56.0 Hydrops fetalis due to isoimmunization
P56.9 Hydrops fetalis due to other and unspecified hemolytic disease
P56.90 Hydrops fetalis due to unspecified hemolytic disease
P56.99 Hydrops fetalis due to other hemolytic disease
P57 Kernicterus

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.