2023 ICD-10-CM Diagnosis Code P58.4

Neonatal jaundice due to drugs or toxins transmitted from mother or given to newborn

    2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
  • P58.4 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • Short description: Neontl jaundice d/t mother drugs/toxins
  • The 2023 edition of ICD-10-CM P58.4 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of P58.4 - other international versions of ICD-10 P58.4 may differ.
Use Additional
Use Additional Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • code for adverse effect, if applicable, to identify drug (T36-T50
    ICD-10-CM Range T36-T50

    Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances

    Code First
    • , for adverse effects, the nature of the adverse effect, such as:
    • adverse effect NOS (T88.7)
    • aspirin gastritis (K29.-)
    • blood disorders (D56-D76)
    • contact dermatitis (L23-L25)
    • dermatitis due to substances taken internally (L27.-)
    • nephropathy (N14.0-N14.2)
    Includes
    • adverse effect of correct substance properly administered
    • poisoning by overdose of substance
    • poisoning by wrong substance given or taken in error
    • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
    Note
    • The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
    Type 1 Excludes
    • toxic reaction to local anesthesia in pregnancy (O29.3-)
    Type 2 Excludes
    • abuse and dependence of psychoactive substances (F10-F19)
    • abuse of non-dependence-producing substances (F55.-)
    • immunodeficiency due to drugs (D84.821)
    • drug reaction and poisoning affecting newborn (P00-P96)
    • pathological drug intoxication (inebriation) (F10-F19)
    Use Additional
    • code(s) to specify:
    • manifestations of poisoning
    • underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
    • underdosing of medication regimen (Z91.12-, Z91.13-)
    • T36 Poisoning by, adverse effect of and unde...
    • T37 Poisoning by, adverse effect of and unde...
    • T38 Poisoning by, adverse effect of and unde...
    • T39 Poisoning by, adverse effect of and unde...
    • T40 Poisoning by, adverse effect of and unde...
    • T41 Poisoning by, adverse effect of and unde...
    • T42 Poisoning by, adverse effect of and unde...
    • T43 Poisoning by, adverse effect of and unde...
    • T44 Poisoning by, adverse effect of and unde...
    • T45 Poisoning by, adverse effect of and unde...
    • T46 Poisoning by, adverse effect of and unde...
    • T47 Poisoning by, adverse effect of and unde...
    • T48 Poisoning by, adverse effect of and unde...
    • T49 Poisoning by, adverse effect of and unde...
    • T50 Poisoning by, adverse effect of and unde...
    with fifth or sixth character 5)
Code First
Code First Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • poisoning due to drug or toxin, if applicable (
    ICD-10-CM Diagnosis Code T36

    Poisoning by, adverse effect of and underdosing of systemic antibiotics

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • antineoplastic antibiotics (T45.1-)
    • locally applied antibiotic NEC (T49.0)
    • topically used antibiotic for ear, nose and throat (T49.6)
    • topically used antibiotic for eye (T49.5)
    T36
    -
    ICD-10-CM Diagnosis Code T65

    Toxic effect of other and unspecified substances

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    T65
    with fifth or sixth character 1-4 or 6)
The following code(s) above P58.4 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to P58.4:
  • P00-P96
    2023 ICD-10-CM Range P00-P96

    Certain conditions originating in the perinatal period

    Includes
    • conditions that have their origin in the fetal or perinatal period (before birth through the first 28 days after birth) even if morbidity occurs later
    Note
    • Codes from this chapter are for use on newborn records only, never on maternal records
    Type 2 Excludes
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • tetanus neonatorum (A33)
    Certain conditions originating in the perinatal period
  • P50-P61
    2023 ICD-10-CM Range P50-P61

    Hemorrhagic and hematological disorders of newborn

    Type 1 Excludes
    • congenital stenosis and stricture of bile ducts (Q44.3)
    • Crigler-Najjar syndrome (E80.5)
    • Dubin-Johnson syndrome (E80.6)
    • Gilbert syndrome (E80.4)
    • hereditary hemolytic anemias (D55-D58)
    Hemorrhagic and hematological disorders of newborn
  • P58
    ICD-10-CM Diagnosis Code P58

    Neonatal jaundice due to other excessive hemolysis

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • jaundice due to isoimmunization (P55-P57)
    Neonatal jaundice due to other excessive hemolysis
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
Code annotations containing back-references to P58.4:
  • Type 1 Excludes: P93
    ICD-10-CM Diagnosis Code P93

    Reactions and intoxications due to drugs administered to newborn

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Includes
    • reactions and intoxications due to drugs administered to fetus affecting newborn
    Type 1 Excludes
    • jaundice due to drugs or toxins transmitted from mother or given to newborn (P58.4-)
    • reactions and intoxications from maternal opiates, tranquilizers and other medication (P04.0-P04.1, P04.4-)
    • withdrawal symptoms from maternal use of drugs of addiction (P96.1)
    • withdrawal symptoms from therapeutic use of drugs in newborn (P96.2)
  • Type 2 Excludes: P04
    ICD-10-CM Diagnosis Code P04

    Newborn affected by noxious substances transmitted via placenta or breast milk

      2016 2017 - Revised Code 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Code First
    • any current condition in newborn, if applicable
    Includes
    • nonteratogenic effects of substances transmitted via placenta
    Type 2 Excludes
    • congenital malformations (Q00-Q99)
    • encounter for observation of newborn for suspected diseases and conditions ruled out (Z05.-)
    • neonatal jaundice from excessive hemolysis due to drugs or toxins transmitted from mother (P58.4)
    • newborn in contact with and (suspected) exposures hazardous to health not transmitted via placenta or breast milk (Z77.-)
ICD-10-CM Codes Adjacent To P58.4
P56.99 Hydrops fetalis due to other hemolytic disease
P57 Kernicterus
P57.0 Kernicterus due to isoimmunization
P57.8 Other specified kernicterus
P57.9 Kernicterus, unspecified
P58 Neonatal jaundice due to other excessive hemolysis
P58.0 Neonatal jaundice due to bruising
P58.1 Neonatal jaundice due to bleeding
P58.2 Neonatal jaundice due to infection
P58.3 Neonatal jaundice due to polycythemia
P58.4 Neonatal jaundice due to drugs or toxins transmitted from mother or given to newborn
P58.41 Neonatal jaundice due to drugs or toxins transmitted from mother
P58.42 Neonatal jaundice due to drugs or toxins given to newborn
P58.5 Neonatal jaundice due to swallowed maternal blood
P58.8 Neonatal jaundice due to other specified excessive hemolysis
P58.9 Neonatal jaundice due to excessive hemolysis, unspecified
P59 Neonatal jaundice from other and unspecified causes
P59.0 Neonatal jaundice associated with preterm delivery
P59.1 Inspissated bile syndrome
P59.2 Neonatal jaundice from other and unspecified hepatocellular damage
P59.20 Neonatal jaundice from unspecified hepatocellular damage

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.