2021 ICD-10-CM Diagnosis Code Q93.3

Deletion of short arm of chromosome 4

    2016 2017 2018 2019 2020 2021 Billable/Specific Code POA Exempt
  • Q93.3 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2021 edition of ICD-10-CM Q93.3 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of Q93.3 - other international versions of ICD-10 Q93.3 may differ.
Applicable To
  • Wolff-Hirschorn syndrome
The following code(s) above Q93.3 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to Q93.3:
  • Q00-Q99
    2021 ICD-10-CM Range Q00-Q99

    Congenital malformations, deformations and chromosomal abnormalities

    Note
    • Codes from this chapter are not for use on maternal records
    Type 2 Excludes
    • inborn errors of metabolism (E70-E88)
    Congenital malformations, deformations and chromosomal abnormalities
  • Q90-Q99
    2021 ICD-10-CM Range Q90-Q99

    Chromosomal abnormalities, not elsewhere classified

    Type 2 Excludes
    • mitochondrial metabolic disorders (E88.4-)
    Chromosomal abnormalities, not elsewhere classified
Approximate Synonyms
  • 4p partial monosomy syndrome
  • Chromosome 4 short arm deletion
Clinical Information
  • A genetic syndrome resulting from a partial deletion on the short arm of chromosome 4 (4p deletion syndrome). It is characterized by mental retardation, microcephaly, seizures, muscle hypotonia, a distinctive facial appearance with prominent forehead and wide set eyes, growth failure with malformations of the spine, hands, and feet, congenital heart defects, and genitourinary malformations.
  • A syndrome caused by large deletions of the telomereic end of the short arm of chromosome 4 (4p) in wolf-hirchhorn syndrome critial regions (whscrs). Several candidate genes have been identified including whsc1 and whsch2 which appear to be responsible for the core phenotype and in combination with other linked and unlinked genes determine the severity and inclusion of rarer phenotypes. Most cases have a characteristic cranio-facial defect often referred to as "greek helmet face" - a combined result of microcephaly, broad forehead, prominent glabella, hypertelorism, high arched eyebrows, short philtrum and micrognathia. In addition there is mental retardation, growth delays, epilepsy, and frequently a wide range of midline and skeletal defects, including hypospadias; congenital heart defects; cleft lip; cleft palate; colobomata; clubfoot; clinodactyly; scoliosis; and kyphosis.
  • Partial deletion of the short arm of chromosome 4 with severe psychomotor deficiency and abnormalities of the craniofacial structures, heart, kidneys, and other organs. The most common defects include asymmetric skull, microcephaly, high forehead, beaked nose, hypertelorism, epicanthal folds, and prominent glabella. The phenotype of proximal interstitial deletion (del4p15) differs from that in the wolf-hirschhorn syndrome and is characterized by distinct facies, multiple minor congenital anomalies, psychomotor retardation and normal growth. Deletion 4p15-16 is expressed in a different phenotype which includes long face, midface hypoplasia, upslanted palpebral fissures, epicanthal folds, large beaked nose, highly arched palate, thick lower lip, micrognathia, broad and short neck, broad hands and feet, tall and thin habitus, delayed growth and mental development, and hypotonia.
Present On Admission
POA Help
"Present On Admission" is defined as present at the time the order for inpatient admission occurs — conditions that develop during an outpatient encounter, including emergency department, observation, or outpatient surgery, are considered POA.
  • Q93.3 is considered exempt from POA reporting.
ICD-10-CM Q93.3 is grouped within Diagnostic Related Group(s) (MS-DRG v38.0):
  • 884 Organic disturbances and intellectual disability

Convert Q93.3 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change

Diagnosis Index entries containing back-references to Q93.3:

ICD-10-CM Codes Adjacent To Q93.3
Q92.6 Marker chromosomes
Q92.61 …… in normal individual
Q92.62 …… in abnormal individual
Q92.7 Triploidy and polyploidy
Q92.8 Other specified trisomies and partial trisomies of autosomes
Q92.9 Trisomy and partial trisomy of autosomes, unspecified
Q93 Monosomies and deletions from the autosomes, not elsewhere classified
Q93.0 Whole chromosome monosomy, nonmosaicism (meiotic nondisjunction)
Q93.1 Whole chromosome monosomy, mosaicism (mitotic nondisjunction)
Q93.2 Chromosome replaced with ring, dicentric or isochromosome
Q93.3 Deletion of short arm of chromosome 4
Q93.4 Deletion of short arm of chromosome 5
Q93.5 Other deletions of part of a chromosome
Q93.51 Angelman syndrome
Q93.59 Other deletions of part of a chromosome
Q93.7 Deletions with other complex rearrangements
Q93.8 Other deletions from the autosomes
Q93.81 Velo-cardio-facial syndrome
Q93.82 Williams syndrome
Q93.88 Other microdeletions
Q93.89 Other deletions from the autosomes

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.