2022 ICD-10-CM Diagnosis Code Q93.88

Other microdeletions

    2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code POA Exempt
  • Q93.88 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2022 edition of ICD-10-CM Q93.88 became effective on October 1, 2021.
  • This is the American ICD-10-CM version of Q93.88 - other international versions of ICD-10 Q93.88 may differ.
Applicable To
  • Miller-Dieker syndrome
  • Smith-Magenis syndrome
The following code(s) above Q93.88 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to Q93.88:
  • Q00-Q99
    2022 ICD-10-CM Range Q00-Q99

    Congenital malformations, deformations and chromosomal abnormalities

    • Codes from this chapter are not for use on maternal records
    Type 2 Excludes
    • inborn errors of metabolism (E70-E88)
    Congenital malformations, deformations and chromosomal abnormalities
  • Q90-Q99
    2022 ICD-10-CM Range Q90-Q99

    Chromosomal abnormalities, not elsewhere classified

    Type 2 Excludes
    • mitochondrial metabolic disorders (E88.4-)
    Chromosomal abnormalities, not elsewhere classified
Approximate Synonyms
  • Smith magenis syndrome
Clinical Information
  • A developmental defect of the brain caused by incomplete neuronal migration and characterized by smoothness of the surface of the brain (lissencephaly) occurring in association with absence of the sulci and gyri (agyria) and thickening of the cerebral cortex with four rather than six layers (pachygyria), microcephaly, characteristic facial appearance, retarded growth and mental development, neurological complications, and multiple abnormalities of the brain, kidneys, heart, gastrointestinal tract, and other organs. Lissencephaly, once considered as synonymous with walker-warburg syndrome and norman-roberts syndrome, is now recognized as a component of several other syndromes. Type i (the classical form) is a component of miller-dieker and norman-roberts syndromes, also occurring as a separate entity; type ii the walker-warburg and muscle-eye-brain syndrome, also occurring in the neu-laxova syndrome.
  • A genetic syndrome caused by an interstitial deletion in chromosome 17p11.2. It is characterized by mild to moderate mental retardation, distinctive facial features (flat head, square face, and deep set-eyes), sleep disturbances, attention deficit disorders, and temper tantrums.
  • A rare chromosomal disorder characterized by abnormalities of the craniofacial area (brachycephaly, prognathism, cleft palate), delays in the acquisition of skills requiring the coordination of mental and muscular activities, mental retardation; most affected individuals experience speech delays that may occur in association with hearing impairment; behavioral abnormalities may include hyperactivity and self-destructive behavior.
  • Complex neurobehavioral disorder characterized by distinctive facial features (facies), developmental delay and intellectual disability. Behavioral phenotypes include sleep disturbance, maladaptive, self-injurious and attention-seeking behaviors. The sleep disturbance is linked to an abnormal circadian secretion pattern of melatonin. The syndrome is associated with de novo deletion or mutation and haploinsufficiency of the retinoic acid-induced 1 protein on chromosome 17p11.2.
  • Deletion of the short arm of chromosome 17. As initially reported, the syndrome consisted mainly of cleft palate and congenital heart defect. The phenotype was later expanded to include brachycephaly, midfacial hypoplasia, broad nasal bridge, highly arched palate, mandibular prognathism, malformed ears, short hands, mental retardation, and other less constant abnormalities.
Present On Admission
POA Help
"Present On Admission" is defined as present at the time the order for inpatient admission occurs — conditions that develop during an outpatient encounter, including emergency department, observation, or outpatient surgery, are considered POA.
  • Q93.88 is considered exempt from POA reporting.
ICD-10-CM Q93.88 is grouped within Diagnostic Related Group(s) (MS-DRG v39.0):
  • 884 Organic disturbances and intellectual disability

Convert Q93.88 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change

Diagnosis Index entries containing back-references to Q93.88:
  • Deletion(s)
    • microdeletions NEC Q93.88
  • Microdeletions NEC Q93.88
  • Syndrome - see also Disease
    • Miller-Dieker Q93.88
    • Smith-Magenis Q93.88

ICD-10-CM Codes Adjacent To Q93.88
Q93.2 Chromosome replaced with ring, dicentric or isochromosome
Q93.3 Deletion of short arm of chromosome 4
Q93.4 Deletion of short arm of chromosome 5
Q93.5 Other deletions of part of a chromosome
Q93.51 Angelman syndrome
Q93.59 Other deletions of part of a chromosome
Q93.7 Deletions with other complex rearrangements
Q93.8 Other deletions from the autosomes
Q93.81 Velo-cardio-facial syndrome
Q93.82 Williams syndrome
Q93.88 Other microdeletions
Q93.89 Other deletions from the autosomes
Q93.9 Deletion from autosomes, unspecified
Q95 Balanced rearrangements and structural markers, not elsewhere classified
Q95.0 Balanced translocation and insertion in normal individual
Q95.1 Chromosome inversion in normal individual
Q95.2 Balanced autosomal rearrangement in abnormal individual
Q95.3 Balanced sex/autosomal rearrangement in abnormal individual
Q95.5 Individual with autosomal fragile site
Q95.8 Other balanced rearrangements and structural markers
Q95.9 Balanced rearrangement and structural marker, unspecified

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.