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ICD-10-CM Codes
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R00-R99
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
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R50-R69
General symptoms and signs
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R59-
Enlarged lymph nodes
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2021 ICD-10-CM Diagnosis Code R59
2021 ICD-10-CM Diagnosis Code R59
Enlarged lymph nodes
2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
- R59 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
- The 2021 edition of ICD-10-CM R59 became effective on October 1, 2020.
- This is the American ICD-10-CM version of R59 - other international versions of ICD-10 R59 may differ.
Type 1 ExcludesType 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as R59. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- lymphadenitis NOS (
ICD-10-CM Diagnosis Code I88.9
Nonspecific lymphadenitis, unspecified
2016 2017 2018 2019 2020 2021 Billable/Specific Code
I88.9) - acute lymphadenitis (
ICD-10-CM Diagnosis Code L04
- L04 Acute lymphadenitis
- L04.0 Acute lymphadenitis of face, head and neck
- L04.1 Acute lymphadenitis of trunk
- L04.2 Acute lymphadenitis of upper limb
- L04.3 Acute lymphadenitis of lower limb
- L04.8 Acute lymphadenitis of other sites
- L04.9 Acute lymphadenitis, unspecified
L04.-) - chronic lymphadenitis (
ICD-10-CM Diagnosis Code I88.1
Chronic lymphadenitis, except mesenteric
2016 2017 2018 2019 2020 2021 Billable/Specific Code
I88.1) - mesenteric (acute) (chronic) lymphadenitis (
ICD-10-CM Diagnosis Code I88.0
Nonspecific mesenteric lymphadenitis
2016 2017 2018 2019 2020 2021 Billable/Specific Code
Applicable To- Mesenteric lymphadenitis (acute)(chronic)
I88.0)
IncludesIncludes Help
"Includes" further defines, or give examples of, the content of the code or category.
The following code(s) above
R59 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
- Applicable To annotations, or
- Code Also annotations, or
- Code First annotations, or
- Excludes1 annotations, or
- Excludes2 annotations, or
- Includes annotations, or
- Note annotations, or
- Use Additional annotations
that may be applicable to
R59:
Clinical Information
- A clinical finding indicating that a lymph node is enlarged. Causes include viral and bacterial infections and cancers that affect the lymph nodes.
- Disease or swelling of the lymph nodes.
- Lymphadenopathy: the abnormal enlargement of lymph nodes.
Code History
- 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
- 2017 (effective 10/1/2016): No change
- 2018 (effective 10/1/2017): No change
- 2019 (effective 10/1/2018): No change
- 2020 (effective 10/1/2019): No change
- 2021 (effective 10/1/2020): No change
Code annotations containing back-references to R59:
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Type 1 Excludes: I88, I89, L04, R22
ICD-10-CM Diagnosis Code I88
Nonspecific lymphadenitis
2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
Type 1 Excludes- acute lymphadenitis, except mesenteric (L04.-)
- enlarged lymph nodes NOS (R59.-)
- human immunodeficiency virus [HIV] disease resulting in generalized lymphadenopathy (B20)
ICD-10-CM Diagnosis Code I89
Other noninfective disorders of lymphatic vessels and lymph nodes
2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
Type 1 Excludes- chylocele, tunica vaginalis (nonfilarial) NOS (N50.89)
- enlarged lymph nodes NOS (R59.-)
- filarial chylocele (B74.-)
- hereditary lymphedema (Q82.0)
ICD-10-CM Diagnosis Code L04
Acute lymphadenitis
2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
Includes- abscess (acute) of lymph nodes, except mesenteric
- acute lymphadenitis, except mesenteric
Type 1 Excludes- chronic or subacute lymphadenitis, except mesenteric (I88.1)
- enlarged lymph nodes (R59.-)
- human immunodeficiency virus [HIV] disease resulting in generalized lymphadenopathy (B20)
- lymphadenitis NOS (I88.9)
- nonspecific mesenteric lymphadenitis (I88.0)
ICD-10-CM Diagnosis Code R22
Localized swelling, mass and lump of skin and subcutaneous tissue
2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
Includes- subcutaneous nodules (localized)(superficial)
Type 1 Excludes- abnormal findings on diagnostic imaging (R90-R93)
- edema (R60.-)
- enlarged lymph nodes (R59.-)
- localized adiposity (E65)
- swelling of joint (M25.4-)
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Type 2 Excludes: D75
ICD-10-CM Diagnosis Code D75
Other and unspecified diseases of blood and blood-forming organs
2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
Type 2 Excludes- acute lymphadenitis (L04.-)
- chronic lymphadenitis (I88.1)
- enlarged lymph nodes (R59.-)
- hypergammaglobulinemia NOS (D89.2)
- lymphadenitis NOS (I88.9)
- mesenteric lymphadenitis (acute) (chronic) (I88.0)
ICD-10-CM Codes Adjacent To R59
R56.00 Simple febrile convulsions
R56.01 Complex febrile convulsions
R56.1 Post traumatic seizures
R56.9 Unspecified convulsions
R57 Shock, not elsewhere classified
R58 Hemorrhage, not elsewhere classified
R59
Enlarged lymph nodes
R59.0 Localized enlarged lymph nodes
R59.1 Generalized enlarged lymph nodes
R59.9 Enlarged lymph nodes, unspecified
R60 Edema, not elsewhere classified
R61 Generalized hyperhidrosis
R62 Lack of expected normal physiological development in childhood and adults
R62.0 Delayed milestone in childhood
Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.