2021

  1. ICD-10-CM Codes
    2. ›
  2. R00-R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
    3. ›
  3. R50-R69 General symptoms and signs
    4. ›
  4. R59- Enlarged lymph nodes
    5. ›
  5. 2021 ICD-10-CM Diagnosis Code R59

2021 ICD-10-CM Diagnosis Code R59

Enlarged lymph nodes

    2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
  • R59 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2021 edition of ICD-10-CM R59 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of R59 - other international versions of ICD-10 R59 may differ.
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as R59. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • lymphadenitis NOS (
    ICD-10-CM Diagnosis Code I88.9

    Nonspecific lymphadenitis, unspecified

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Lymphadenitis NOS
    I88.9
    )
  • acute lymphadenitis (
    ICD-10-CM Diagnosis Code L04
    • L04 Acute lymphadenitis
      • L04.0 Acute lymphadenitis of face, head and neck
      • L04.1 Acute lymphadenitis of trunk
      • L04.2 Acute lymphadenitis of upper limb
      • L04.3 Acute lymphadenitis of lower limb
      • L04.8 Acute lymphadenitis of other sites
      • L04.9 Acute lymphadenitis, unspecified
    L04.-
    )
  • chronic lymphadenitis (
    ICD-10-CM Diagnosis Code I88.1

    Chronic lymphadenitis, except mesenteric

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Adenitis
    • Lymphadenitis
    I88.1
    )
  • mesenteric (acute) (chronic) lymphadenitis (
    ICD-10-CM Diagnosis Code I88.0

    Nonspecific mesenteric lymphadenitis

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Mesenteric lymphadenitis (acute)(chronic)
    I88.0
    )
Includes
Includes Help
"Includes" further defines, or give examples of, the content of the code or category.
  • swollen glands
The following code(s) above R59 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to R59:
  • R00-R99
    2021 ICD-10-CM Range R00-R99

    Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

    Note
    • This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
    • Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
    • The conditions and signs or symptoms included in categories R00-R94 consist of:
    • (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
    • (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
    • (c) provisional diagnosis in a patient who failed to return for further investigation or care;
    • (d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
    • (e) cases in which a more precise diagnosis was not available for any other reason;
    • (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.
    Type 2 Excludes
    • abnormal findings on antenatal screening of mother (O28.-)
    • certain conditions originating in the perinatal period (P04-P96)
    • signs and symptoms classified in the body system chapters
    • signs and symptoms of breast (N63, N64.5)
    Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
Clinical Information
  • A clinical finding indicating that a lymph node is enlarged. Causes include viral and bacterial infections and cancers that affect the lymph nodes.
  • Disease or swelling of the lymph nodes.
  • Lymphadenopathy: the abnormal enlargement of lymph nodes.
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
Code annotations containing back-references to R59:
  • Type 1 Excludes: I88
    , I89
    , L04
    , R22
    ICD-10-CM Diagnosis Code I88

    Nonspecific lymphadenitis

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • acute lymphadenitis, except mesenteric (L04.-)
    • enlarged lymph nodes NOS (R59.-)
    • human immunodeficiency virus [HIV] disease resulting in generalized lymphadenopathy (B20)
    ICD-10-CM Diagnosis Code I89

    Other noninfective disorders of lymphatic vessels and lymph nodes

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • chylocele, tunica vaginalis (nonfilarial) NOS (N50.89)
    • enlarged lymph nodes NOS (R59.-)
    • filarial chylocele (B74.-)
    • hereditary lymphedema (Q82.0)
    ICD-10-CM Diagnosis Code L04

    Acute lymphadenitis

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Includes
    • abscess (acute) of lymph nodes, except mesenteric
    • acute lymphadenitis, except mesenteric
    Type 1 Excludes
    • chronic or subacute lymphadenitis, except mesenteric (I88.1)
    • enlarged lymph nodes (R59.-)
    • human immunodeficiency virus [HIV] disease resulting in generalized lymphadenopathy (B20)
    • lymphadenitis NOS (I88.9)
    • nonspecific mesenteric lymphadenitis (I88.0)
    ICD-10-CM Diagnosis Code R22

    Localized swelling, mass and lump of skin and subcutaneous tissue

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Includes
    • subcutaneous nodules (localized)(superficial)
    Type 1 Excludes
    • abnormal findings on diagnostic imaging (R90-R93)
    • edema (R60.-)
    • enlarged lymph nodes (R59.-)
    • localized adiposity (E65)
    • swelling of joint (M25.4-)
  • Type 2 Excludes: D75
    ICD-10-CM Diagnosis Code D75

    Other and unspecified diseases of blood and blood-forming organs

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 2 Excludes
    • acute lymphadenitis (L04.-)
    • chronic lymphadenitis (I88.1)
    • enlarged lymph nodes (R59.-)
    • hypergammaglobulinemia NOS (D89.2)
    • lymphadenitis NOS (I88.9)
    • mesenteric lymphadenitis (acute) (chronic) (I88.0)
ICD-10-CM Codes Adjacent To R59
R56.00 Simple febrile convulsions
R56.01 Complex febrile convulsions
R56.1 Post traumatic seizures
R56.9 Unspecified convulsions
R57 Shock, not elsewhere classified
R57.0 Cardiogenic shock
R57.1 Hypovolemic shock
R57.8 Other shock
R57.9 Shock, unspecified
R58 Hemorrhage, not elsewhere classified
R59 Enlarged lymph nodes
R59.0 Localized enlarged lymph nodes
R59.1 Generalized enlarged lymph nodes
R59.9 Enlarged lymph nodes, unspecified
R60 Edema, not elsewhere classified
R60.0 Localized edema
R60.1 Generalized edema
R60.9 Edema, unspecified
R61 Generalized hyperhidrosis
R62 Lack of expected normal physiological development in childhood and adults
R62.0 Delayed milestone in childhood

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

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