2023 ICD-10-CM Diagnosis Code R64

Cachexia

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • R64 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2023 edition of ICD-10-CM R64 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of R64 - other international versions of ICD-10 R64 may differ.
Applicable To
  • Wasting syndrome
Code First
Code First Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • underlying condition, if known
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as R64. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • abnormal weight loss (
    ICD-10-CM Diagnosis Code R63.4

    Abnormal weight loss

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    R63.4
    )
  • nutritional marasmus (
    ICD-10-CM Diagnosis Code E41

    Nutritional marasmus

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Applicable To
    • Severe malnutrition with marasmus
    Type 1 Excludes
    • marasmic kwashiorkor (E42)
    E41
    )
The following code(s) above R64 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to R64:
  • R00-R99
    2023 ICD-10-CM Range R00-R99

    Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

    Note
    • This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
    • Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
    • The conditions and signs or symptoms included in categories R00-R94 consist of:
    • (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
    • (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
    • (c) provisional diagnosis in a patient who failed to return for further investigation or care;
    • (d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
    • (e) cases in which a more precise diagnosis was not available for any other reason;
    • (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.
    Type 2 Excludes
    • abnormal findings on antenatal screening of mother (O28.-)
    • certain conditions originating in the perinatal period (P04-P96)
    • signs and symptoms classified in the body system chapters
    • signs and symptoms of breast (N63, N64.5)
    Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
Approximate Synonyms
  • Aids wasting disease
  • Cachexia (wasting syndrome)
  • Cachexia associated with aids
Clinical Information
  • A condition of involuntary weight loss of greater then 10% of baseline body weight. It is characterized by atrophy of muscles and depletion of lean body mass. Wasting is a sign of malnutrition as a result of inadequate dietary intake, malabsorption, or hypermetabolism.
  • General ill health, malnutrition, and weight loss, usually associated with chronic disease.
  • State of general ill health characterized by malnutrition, weakness, and emaciation; occurs during the course of a chronic disease.
  • The loss of body weight and muscle mass frequently seen in patients with cancer, aids, or other diseases.
ICD-10-CM R64 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 947 Signs and symptoms with mcc
  • 948 Signs and symptoms without mcc

Convert R64 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change

Diagnosis Index entries containing back-references to R64:

ICD-10-CM Codes Adjacent To R64
R63.2 Polyphagia
R63.3 Feeding difficulties
R63.30 …… unspecified
R63.31 Pediatric feeding disorder, acute
R63.32 Pediatric feeding disorder, chronic
R63.39 Other feeding difficulties
R63.4 Abnormal weight loss
R63.5 Abnormal weight gain
R63.6 Underweight
R63.8 Other symptoms and signs concerning food and fluid intake
R64 Cachexia
R65 Symptoms and signs specifically associated with systemic inflammation and infection
R65.1 Systemic inflammatory response syndrome (SIRS) of non-infectious origin
R65.10 …… without acute organ dysfunction
R65.11 …… with acute organ dysfunction
R65.2 Severe sepsis
R65.20 …… without septic shock
R65.21 …… with septic shock
R68 Other general symptoms and signs
R68.0 Hypothermia, not associated with low environmental temperature
R68.1 Nonspecific symptoms peculiar to infancy

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.