2023

  1. ICD-10-CM Codes
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  2. R00-R99
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  3. R70-R79
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  4. R74-
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  5. 2023 ICD-10-CM Diagnosis Code R74.8

2023 ICD-10-CM Diagnosis Code R74.8

Abnormal levels of other serum enzymes

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • R74.8 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2023 edition of ICD-10-CM R74.8 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of R74.8 - other international versions of ICD-10 R74.8 may differ.
Applicable To
  • Abnormal level of acid phosphatase
  • Abnormal level of alkaline phosphatase
  • Abnormal level of amylase
  • Abnormal level of lipase [triacylglycerol lipase]
The following code(s) above R74.8 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to R74.8:
  • R00-R99
    2023 ICD-10-CM Range R00-R99

    Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

    Note
    • This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
    • Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
    • The conditions and signs or symptoms included in categories R00-R94 consist of:
    • (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
    • (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
    • (c) provisional diagnosis in a patient who failed to return for further investigation or care;
    • (d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
    • (e) cases in which a more precise diagnosis was not available for any other reason;
    • (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.
    Type 2 Excludes
    • abnormal findings on antenatal screening of mother (O28.-)
    • certain conditions originating in the perinatal period (P04-P96)
    • signs and symptoms classified in the body system chapters
    • signs and symptoms of breast (N63, N64.5)
    Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
  • R70-R79
    2023 ICD-10-CM Range R70-R79

    Abnormal findings on examination of blood, without diagnosis

    Type 2 Excludes
    • abnormal findings on antenatal screening of mother (O28.-)
    • abnormalities of lipids (E78.-)
    • abnormalities of platelets and thrombocytes (D69.-)
    • abnormalities of white blood cells classified elsewhere (D70-D72)
    • coagulation hemorrhagic disorders (D65-D68)
    • diagnostic abnormal findings classified elsewhere - see Alphabetical Index
    • hemorrhagic and hematological disorders of newborn (P50-P61)
    Abnormal findings on examination of blood, without diagnosis
Approximate Synonyms
  • Alkaline phosphatase raised
  • Elevated alkaline phosphatase
  • Elevated amylase
  • Elevated cpk
  • Hyperamylasemia
  • Increased creatine kinase level
  • Macroamylasemia
  • Serum amylase raised
ICD-10-CM R74.8 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 947 Signs and symptoms with mcc
  • 948 Signs and symptoms without mcc

Convert R74.8 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change

Diagnosis Index entries containing back-references to R74.8:
  • Abnormal, abnormality, abnormalities - see also Anomaly
    • serum level (of)
      • enzymes R74.9
        ICD-10-CM Diagnosis Code R74.9

        Abnormal serum enzyme level, unspecified

          2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
        • specified NEC R74.8
      • acid phosphatase R74.8
      • alkaline phosphatase R74.8
      • amylase R74.8
      • lipase R74.8
      • triacylglycerol lipase R74.8
  • Elevated, elevation
    • liver function
      • test R79.89
        ICD-10-CM Diagnosis Code R79.89

        Other specified abnormal findings of blood chemistry

          2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
        • alkaline phosphatase R74.8
        • hepatic enzyme R74.8

ICD-10-CM Codes Adjacent To R74.8
R73.0 Abnormal glucose
R73.01 Impaired fasting glucose
R73.02 Impaired glucose tolerance (oral)
R73.03 Prediabetes
R73.09 Other abnormal glucose
R73.9 Hyperglycemia, unspecified
R74 Abnormal serum enzyme levels
R74.0 Nonspecific elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
R74.01 Elevation of levels of liver transaminase levels
R74.02 Elevation of levels of lactic acid dehydrogenase [LDH]
R74.8 Abnormal levels of other serum enzymes
R74.9 Abnormal serum enzyme level, unspecified
R75 Inconclusive laboratory evidence of human immunodeficiency virus [HIV]
R76 Other abnormal immunological findings in serum
R76.0 Raised antibody titer
R76.1 Nonspecific reaction to test for tuberculosis
R76.11 Nonspecific reaction to tuberculin skin test without active tuberculosis
R76.12 Nonspecific reaction to cell mediated immunity measurement of gamma interferon antigen response without active tuberculosis
R76.8 Other specified abnormal immunological findings in serum
R76.9 Abnormal immunological finding in serum, unspecified
R77 Other abnormalities of plasma proteins

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

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