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ICD-10-CM Codes
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S00-T88
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T36-T50
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T45-
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2023 ICD-10-CM Diagnosis Code T45.1X5
2023 ICD-10-CM Diagnosis Code T45.1X5
Adverse effect of antineoplastic and immunosuppressive drugs
2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
- T45.1X5 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
- The 2023 edition of ICD-10-CM T45.1X5 became effective on October 1, 2022.
- This is the American ICD-10-CM version of T45.1X5 - other international versions of ICD-10 T45.1X5 may differ.
The following code(s) above
T45.1X5 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
- Applicable To annotations, or
- Code Also annotations, or
- Code First annotations, or
- Excludes1 annotations, or
- Excludes2 annotations, or
- Includes annotations, or
- Note annotations, or
- Use Additional annotations
that may be applicable to
T45.1X5:
- S00-T88
2023 ICD-10-CM Range S00-T88
Injury, poisoning and certain other consequences of external causesNote- Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
Use Additional- code to identify any retained foreign body, if applicable (Z18.-)
- T36-T50
2023 ICD-10-CM Range T36-T50
Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substancesCode First- , for adverse effects, the nature of the adverse effect, such as:
- adverse effect NOS (T88.7)
- aspirin gastritis (K29.-)
- blood disorders (D56-D76)
- contact dermatitis (L23-L25)
- dermatitis due to substances taken internally (L27.-)
- nephropathy (N14.0-N14.2)
Includes- adverse effect of correct substance properly administered
- poisoning by overdose of substance
- poisoning by wrong substance given or taken in error
- underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
Note- The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
Type 1 Excludes- toxic reaction to local anesthesia in pregnancy (O29.3-)
Type 2 Excludes- abuse and dependence of psychoactive substances (F10-F19)
- abuse of non-dependence-producing substances (F55.-)
- immunodeficiency due to drugs (D84.821)
- drug reaction and poisoning affecting newborn (P00-P96)
- pathological drug intoxication (inebriation) (F10-F19)
Use Additional- code(s) to specify:
- manifestations of poisoning
- underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
- underdosing of medication regimen (Z91.12-, Z91.13-)
- T45.1
ICD-10-CM Diagnosis Code T45.1
Poisoning by, adverse effect of and underdosing of antineoplastic and immunosuppressive drugs
2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
Type 1 Excludes- poisoning by, adverse effect of and underdosing of tamoxifen (T38.6)
- 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
- 2017 (effective 10/1/2016): No change
- 2018 (effective 10/1/2017): No change
- 2019 (effective 10/1/2018): No change
- 2020 (effective 10/1/2019): No change
- 2021 (effective 10/1/2020): No change
- 2022 (effective 10/1/2021): No change
- 2023 (effective 10/1/2022): No change
Code annotations containing back-references to T45.1X5:
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Use Additional: D70.1, E88.3, K12.31
ICD-10-CM Diagnosis Code D70.1
Agranulocytosis secondary to cancer chemotherapy
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Use Additional- code for adverse effect, if applicable, to identify drug (T45.1X5)
ICD-10-CM Diagnosis Code E88.3
Tumor lysis syndrome
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To- Tumor lysis syndrome (spontaneous)
- Tumor lysis syndrome following antineoplastic drug chemotherapy
Use Additional- code for adverse effect, if applicable, to identify drug (T45.1X5)
ICD-10-CM Diagnosis Code K12.31
Oral mucositis (ulcerative) due to antineoplastic therapy
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Use Additional- code for adverse effect, if applicable, to identify antineoplastic and immunosuppressive drugs (T45.1X5)
ICD-10-CM Codes Adjacent To T45.1X5
T45.1X3 Poisoning by antineoplastic and immunosuppressive drugs, assault
T45.1X4 Poisoning by antineoplastic and immunosuppressive drugs, undetermined
T45.1X5
Adverse effect of antineoplastic and immunosuppressive drugs
T45.1X6 Underdosing of antineoplastic and immunosuppressive drugs
T45.2 Poisoning by, adverse effect of and underdosing of vitamins
T45.2X Poisoning by, adverse effect of and underdosing of vitamins
T45.2X1 Poisoning by vitamins, accidental (unintentional)
Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.
