2021

  1. ICD-10-CM Codes
    2. ›
  2. S00-T88 Injury, poisoning and certain other consequences of external causes
    3. ›
  3. T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
    4. ›
  4. T45- Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified
    5. ›
  5. 2021 ICD-10-CM Diagnosis Code T45.515

2021 ICD-10-CM Diagnosis Code T45.515

Adverse effect of anticoagulants

    2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
  • T45.515 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2021 edition of ICD-10-CM T45.515 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of T45.515 - other international versions of ICD-10 T45.515 may differ.
The following code(s) above T45.515 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to T45.515:
  • S00-T88
    2021 ICD-10-CM Range S00-T88

    Injury, poisoning and certain other consequences of external causes

    Note
    • Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
    Type 1 Excludes
    Use Additional
    • code to identify any retained foreign body, if applicable (Z18.-)
    Injury, poisoning and certain other consequences of external causes
  • T36-T50
    2021 ICD-10-CM Range T36-T50

    Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances

    Code First
    • , for adverse effects, the nature of the adverse effect, such as:
    • adverse effect NOS (T88.7)
    • aspirin gastritis (K29.-)
    • blood disorders (D56-D76)
    • contact dermatitis (L23-L25)
    • dermatitis due to substances taken internally (L27.-)
    • nephropathy (N14.0-N14.2)
    Includes
    • adverse effect of correct substance properly administered
    • poisoning by overdose of substance
    • poisoning by wrong substance given or taken in error
    • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
    Note
    • The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
    Type 1 Excludes
    • toxic reaction to local anesthesia in pregnancy (O29.3-)
    Type 2 Excludes
    • abuse and dependence of psychoactive substances (F10-F19)
    • abuse of non-dependence-producing substances (F55.-)
    • immunodeficiency due to drugs (D84.821)
    • drug reaction and poisoning affecting newborn (P00-P96)
    • pathological drug intoxication (inebriation) (F10-F19)
    Use Additional
    • code(s) to specify:
    • manifestations of poisoning
    • underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
    • underdosing of medication regimen (Z91.12-, Z91.13-)
    Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
Code annotations containing back-references to T45.515:
  • Use Additional: D68.32
    ICD-10-CM Diagnosis Code D68.32

    Hemorrhagic disorder due to extrinsic circulating anticoagulants

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Drug-induced hemorrhagic disorder
    • Hemorrhagic disorder due to increase in anti-IIa
    • Hemorrhagic disorder due to increase in anti-Xa
    • Hyperheparinemia
    Use Additional
    • code for adverse effect, if applicable, to identify drug (T45.515, T45.525)
ICD-10-CM Codes Adjacent To T45.515
T45.512D …… subsequent encounter
T45.512S …… sequela
T45.513 Poisoning by anticoagulants, assault
T45.513A …… initial encounter
T45.513D …… subsequent encounter
T45.513S …… sequela
T45.514 Poisoning by anticoagulants, undetermined
T45.514A …… initial encounter
T45.514D …… subsequent encounter
T45.514S …… sequela
T45.515 Adverse effect of anticoagulants
T45.515A …… initial encounter
T45.515D …… subsequent encounter
T45.515S …… sequela
T45.516 Underdosing of anticoagulants
T45.516A …… initial encounter
T45.516D …… subsequent encounter
T45.516S …… sequela
T45.52 Poisoning by, adverse effect of and underdosing of antithrombotic drugs
T45.521 Poisoning by antithrombotic drugs, accidental (unintentional)
T45.521A …… initial encounter

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

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