2020 ICD-10-CM Diagnosis Code T78.2

Anaphylactic shock, unspecified

    2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
  • T78.2 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2020 edition of ICD-10-CM T78.2 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of T78.2 - other international versions of ICD-10 T78.2 may differ.
Applicable To
  • Allergic shock
  • Anaphylactic reaction
  • Anaphylaxis
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as T78.2. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (
    ICD-10-CM Diagnosis Code T88.6

    Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Applicable To
    • Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
    • Anaphylactoid reaction NOS
    Type 1 Excludes
    • anaphylactic reaction due to serum (T80.5-)
    • anaphylactic shock or reaction due to adverse food reaction (T78.0-)
    Use Additional
    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
    T88.6
    )
  • anaphylactic reaction or shock due to adverse food reaction (
    ICD-10-CM Diagnosis Code T78.0

    Anaphylactic reaction due to food

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Applicable To
    • Anaphylactic reaction due to adverse food reaction
    • Anaphylactic shock or reaction due to nonpoisonous foods
    • Anaphylactoid reaction due to food
    T78.0-
    )
  • anaphylactic reaction or shock due to serum (
    ICD-10-CM Diagnosis Code T80.5

    Anaphylactic reaction due to serum

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Applicable To
    • Allergic shock due to serum
    • Anaphylactic shock due to serum
    • Anaphylactoid reaction due to serum
    • Anaphylaxis due to serum
    Type 1 Excludes
    • ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-)
    • allergic reaction or shock NOS (T78.2)
    • anaphylactic reaction or shock NOS (T78.2)
    • anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6)
    • other serum reaction (T80.6-)
    T80.5-
    )
The following code(s) above T78.2 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to T78.2:
  • S00-T88
    2020 ICD-10-CM Range S00-T88

    Injury, poisoning and certain other consequences of external causes

    Note
    • Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
    Type 1 Excludes
    Use Additional
    • code to identify any retained foreign body, if applicable (Z18.-)
    Injury, poisoning and certain other consequences of external causes
  • T78
    ICD-10-CM Diagnosis Code T78

    Adverse effects, not elsewhere classified

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Type 2 Excludes
    • complications of surgical and medical care NEC (T80-T88)
    Adverse effects, not elsewhere classified
Clinical Information
  • A disorder characterized by an acute inflammatory reaction resulting from the release of histamine and histamine-like substances from mast cells, causing a hypersensitivity immune response. Clinically, it presents with breathing difficulty, dizziness, hypotension, cyanosis and loss of consciousness and may lead to death.
  • A manifestation of immediate hypersensitivity in which exposure of a sensitized individual to a specific antigen or hapten results in urticaria, pruritis and angioedema, followed by vascular collapse and shock often accompanied by life threatening respiratory distress.
  • A severe and sometimes life-threatening immune system reaction to an antigen that a person has been previously exposed to. The reaction may include itchy skin, edema, collapsed blood vessels, fainting, difficulty in breathing, and death.
  • An acute hypersensitivity reaction due to exposure to a previously encountered antigen. The reaction may include rapidly progressing urticaria, respiratory distress, vascular collapse, systemic shock, and death.
  • An acute inflammatory reaction resulting from combination of a soluble antigen with ige bound to a mast cell that leads to degranulation of the mast cell and release of histamine and histamine like substances, causing localized or global hypersensitivity immune reponses.
  • An acute inflammatory reaction resulting from the release of histamine and histamine-like substances from mast cells, causing a hypersensitivity immune response. Clinically, it presents with breathing difficulty, dizziness, hypotension, cyanosis and loss of consciousness, and may lead to death.
  • Immunologic or allergic reaction to antigens such as drugs or foreign proteins to which a hypersensitivity has been established by previous contact.
  • Obsolete. Extreme immunological sensitivity of the body or tissues to the reintroduction of an antigen. It is a form of anamnestic reaction and is accompanied by pathological changes in tissues or organs due to the release of pharmacologically active substances. [isbn:0198506732 "oxford dictionary of biochemistry and molecular biology"]
  • Obsolete. Extreme immunological sensitivity of the body or tissues to the reintroduction of an antigen. It is a form of anamnestic reaction and is accompanied by pathological changes in tissues or organs due to the release of pharmacologically active substances. [isbn:0198506732]
  • Pertaining to anaphylaxis.
  • Systemic anaphylaxis is the most dramatic example of an immediate hypersensitivity reaction; is uncommon and unexpected in nature and occasionally results in a fatal outcome.
  • Systemic anaphylaxis is the most dramatic example of an immediate hypersensitivity reaction; is uncommon and unexpected in nature and occasionally results in a fatal outcome. (cdrh)
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
Code annotations containing back-references to T78.2:
  • Type 1 Excludes: T79.4
    , T80.5
    , T80.5
    , T81.1
    , R57
    ICD-10-CM Diagnosis Code T79.4

    Traumatic shock

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Applicable To
    • Shock (immediate) (delayed) following injury
    Type 1 Excludes
    • anaphylactic shock due to adverse food reaction (T78.0-)
    • anaphylactic shock due to correct medicinal substance properly administered (T88.6)
    • anaphylactic shock due to serum (T80.5-)
    • anaphylactic shock NOS (T78.2)
    • anesthetic shock (T88.2)
    • electric shock (T75.4)
    • nontraumatic shock NEC (R57.-)
    • obstetric shock (O75.1)
    • postprocedural shock (T81.1-)
    • septic shock (R65.21)
    • shock complicating abortion or ectopic or molar pregnancy (O00-O07, O08.3)
    • shock due to lightning (T75.01)
    • shock NOS (R57.9)
    ICD-10-CM Diagnosis Code T80.5

    Anaphylactic reaction due to serum

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Applicable To
    • Allergic shock due to serum
    • Anaphylactic shock due to serum
    • Anaphylactoid reaction due to serum
    • Anaphylaxis due to serum
    Type 1 Excludes
    • ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-)
    • allergic reaction or shock NOS (T78.2)
    • anaphylactic reaction or shock NOS (T78.2)
    • anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6)
    • other serum reaction (T80.6-)
    ICD-10-CM Diagnosis Code T80.5

    Anaphylactic reaction due to serum

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Applicable To
    • Allergic shock due to serum
    • Anaphylactic shock due to serum
    • Anaphylactoid reaction due to serum
    • Anaphylaxis due to serum
    Type 1 Excludes
    • ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-)
    • allergic reaction or shock NOS (T78.2)
    • anaphylactic reaction or shock NOS (T78.2)
    • anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6)
    • other serum reaction (T80.6-)
    ICD-10-CM Diagnosis Code T81.1

    Postprocedural shock

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Applicable To
    • Shock during or resulting from a procedure, not elsewhere classified
    Type 1 Excludes
    • anaphylactic shock NOS (T78.2)
    • anaphylactic shock due to correct substance properly administered (T88.6)
    • anaphylactic shock due to serum (T80.5-)
    • anesthetic shock (T88.2)
    • electric shock (T75.4)
    • obstetric shock (O75.1)
    • septic shock (R65.21)
    • shock following abortion or ectopic or molar pregnancy (O00-O07, O08.3)
    • traumatic shock (T79.4)
    ICD-10-CM Diagnosis Code R57

    Shock, not elsewhere classified

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • anaphylactic shock NOS (T78.2)
    • anaphylactic reaction or shock due to adverse food reaction (T78.0-)
    • anaphylactic shock due to adverse effect of correct drug or medicament properly administered (T88.6)
    • anaphylactic shock due to serum (T80.5-)
    • anesthetic shock (T88.3)
    • electric shock (T75.4)
    • obstetric shock (O75.1)
    • postprocedural shock (T81.1-)
    • psychic shock (F43.0)
    • shock complicating or following ectopic or molar pregnancy (O00-O07, O08.3)
    • shock due to lightning (T75.01)
    • traumatic shock (T79.4)
    • toxic shock syndrome (A48.3)

Diagnosis Index entries containing back-references to T78.2:
  • Allergy, allergic (reaction) (to) T78.40
    ICD-10-CM Diagnosis Code T78.40

    Allergy, unspecified

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Applicable To
    • Allergic reaction NOS
    • Hypersensitivity NOS
    • shock (anaphylactic) T78.2
    • anaphylactic reaction or shock T78.2
  • Shock R57.9
    ICD-10-CM Diagnosis Code R57.9

    Shock, unspecified

      2016 2017 2018 2019 2020 Billable/Specific Code
    Applicable To
    • Failure of peripheral circulation NOS

ICD-10-CM Codes Adjacent To T78.2
T78.08XD …… subsequent encounter
T78.08XS …… sequela
T78.09 Anaphylactic reaction due to other food products
T78.09XA …… initial encounter
T78.09XD …… subsequent encounter
T78.09XS …… sequela
T78.1 Other adverse food reactions, not elsewhere classified
T78.1XXA …… initial encounter
T78.1XXD …… subsequent encounter
T78.1XXS …… sequela
T78.2 Anaphylactic shock, unspecified
T78.2XXA …… initial encounter
T78.2XXD …… subsequent encounter
T78.2XXS …… sequela
T78.3 Angioneurotic edema
T78.3XXA …… initial encounter
T78.3XXD …… subsequent encounter
T78.3XXS …… sequela
T78.4 Other and unspecified allergy
T78.40 Allergy, unspecified
T78.40XA …… initial encounter

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.