1. ICD-10-CM Codes
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2. S00-T88
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3. T66-T78
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4. T78-
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5. 2023 ICD-10-CM Diagnosis Code T78.2

2023 ICD-10-CM Diagnosis Code T78.2

Anaphylactic shock, unspecified

2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code

• T78.2 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
• The 2023 edition of ICD-10-CM T78.2 became effective on October 1, 2022.
• This is the American ICD-10-CM version of T78.2 - other international versions of ICD-10 T78.2 may differ.

• A disorder characterized by an acute inflammatory reaction resulting from the release of histamine and histamine-like substances from mast cells, causing a hypersensitivity immune response. Clinically, it presents with breathing difficulty, dizziness, hypotension, cyanosis and loss of consciousness and may lead to death.
• A manifestation of immediate hypersensitivity in which exposure of a sensitized individual to a specific antigen or hapten results in urticaria, pruritis and angioedema, followed by vascular collapse and shock often accompanied by life threatening respiratory distress.
• A severe and sometimes life-threatening immune system reaction to an antigen that a person has been previously exposed to. The reaction may include itchy skin, edema, collapsed blood vessels, fainting, difficulty in breathing, and death.
• An acute hypersensitivity reaction due to exposure to a previously encountered antigen. The reaction may include rapidly progressing urticaria, respiratory distress, vascular collapse, systemic shock, and death.
• An acute inflammatory reaction resulting from combination of a soluble antigen with ige bound to a mast cell that leads to degranulation of the mast cell and release of histamine and histamine like substances, causing localized or global hypersensitivity immune reponses.
• An acute inflammatory reaction resulting from the release of histamine and histamine-like substances from mast cells, causing a hypersensitivity immune response. Clinically, it presents with breathing difficulty, dizziness, hypotension, cyanosis and loss of consciousness, and may lead to death.
• Immunologic or allergic reaction to antigens such as drugs or foreign proteins to which a hypersensitivity has been established by previous contact.
• Obsolete. Extreme immunological sensitivity of the body or tissues to the reintroduction of an antigen. It is a form of anamnestic reaction and is accompanied by pathological changes in tissues or organs due to the release of pharmacologically active substances. [isbn:0198506732 "oxford dictionary of biochemistry and molecular biology"]
• Obsolete. Extreme immunological sensitivity of the body or tissues to the reintroduction of an antigen. It is a form of anamnestic reaction and is accompanied by pathological changes in tissues or organs due to the release of pharmacologically active substances. [isbn:0198506732]
• Pertaining to anaphylaxis.
• Systemic anaphylaxis is the most dramatic example of an immediate hypersensitivity reaction; is uncommon and unexpected in nature and occasionally results in a fatal outcome.
• Systemic anaphylaxis is the most dramatic example of an immediate hypersensitivity reaction; is uncommon and unexpected in nature and occasionally results in a fatal outcome. (cdrh)

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change
• 2021 (effective 10/1/2020): No change
• 2022 (effective 10/1/2021): No change
• 2023 (effective 10/1/2022): No change

• Type 1 Excludes: R57
  , T79.4
  , T80.5
  , T80.5
  , T81.1
  ICD-10-CM Diagnosis Code R57

  Shock, not elsewhere classified

  2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code

  Type 1 Excludes

  • anaphylactic shock NOS (T78.2)
  • anaphylactic reaction or shock due to adverse food reaction (T78.0-)
  • anaphylactic shock due to adverse effect of correct drug or medicament properly administered (T88.6)
  • anaphylactic shock due to serum (T80.5-)
  • electric shock (T75.4)
  • obstetric shock (O75.1)
  • postprocedural shock (T81.1-)
  • psychic shock (F43.0)
  • shock complicating or following ectopic or molar pregnancy (O00-O07, O08.3)
  • shock due to anesthesia (T88.2)
  • shock due to lightning (T75.01)
  • traumatic shock (T79.4)
  • toxic shock syndrome (A48.3)
  ICD-10-CM Diagnosis Code T79.4

  Traumatic shock

  2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code

  Applicable To

  • Shock (immediate) (delayed) following injury

  Type 1 Excludes

  • anaphylactic shock due to adverse food reaction (T78.0-)
  • anaphylactic shock due to correct medicinal substance properly administered (T88.6)
  • anaphylactic shock due to serum (T80.5-)
  • anaphylactic shock NOS (T78.2)
  • electric shock (T75.4)
  • nontraumatic shock NEC (R57.-)
  • obstetric shock (O75.1)
  • postprocedural shock (T81.1-)
  • septic shock (R65.21)
  • shock complicating abortion or ectopic or molar pregnancy (O00-O07, O08.3)
  • shock due to anesthesia (T88.2)
  • shock due to lightning (T75.01)
  • shock NOS (R57.9)
  ICD-10-CM Diagnosis Code T80.5

  Anaphylactic reaction due to serum

  2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code

  Applicable To

  • Allergic shock due to serum
  • Anaphylactic shock due to serum
  • Anaphylactoid reaction due to serum
  • Anaphylaxis due to serum

  Type 1 Excludes

  • ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-)
  • allergic reaction or shock NOS (T78.2)
  • anaphylactic reaction or shock NOS (T78.2)
  • anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6)
  • other serum reaction (T80.6-)
  ICD-10-CM Diagnosis Code T80.5

  Anaphylactic reaction due to serum

  2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code

  Applicable To

  • Allergic shock due to serum
  • Anaphylactic shock due to serum
  • Anaphylactoid reaction due to serum
  • Anaphylaxis due to serum

  Type 1 Excludes

  • ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-)
  • allergic reaction or shock NOS (T78.2)
  • anaphylactic reaction or shock NOS (T78.2)
  • anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6)
  • other serum reaction (T80.6-)
  ICD-10-CM Diagnosis Code T81.1

  Postprocedural shock

  2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code

  Applicable To

  • Shock during or resulting from a procedure, not elsewhere classified

  Type 1 Excludes

  • anaphylactic shock NOS (T78.2)
  • anaphylactic shock due to correct substance properly administered (T88.6)
  • anaphylactic shock due to serum (T80.5-)
  • electric shock (T75.4)
  • obstetric shock (O75.1)
  • septic shock (R65.21)
  • shock due to anesthesia (T88.2)
  • shock following abortion or ectopic or molar pregnancy (O00-O07, O08.3)
  • traumatic shock (T79.4)

• Allergy, allergic (reaction) (to) T78.40
  ICD-10-CM Diagnosis Code T78.40

  Allergy, unspecified

  2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code

  Applicable To

  • Allergic reaction NOS
  • Hypersensitivity NOS
  • shock (anaphylactic) T78.2
  • anaphylactic reaction or shock T78.2
• Shock R57.9
  ICD-10-CM Diagnosis Code R57.9

  Shock, unspecified

  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

  Applicable To

  • Failure of peripheral circulation NOS
  • anaphylactic T78.2

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.