ICD-10-CM Codes
S00-T88 Injury, poisoning and certain other consequences of external causes
T66-T78 Other and unspecified effects of external causes
T78- Adverse effects, not elsewhere classified
2022 ICD-10-CM Diagnosis Code T78.3

2022 ICD-10-CM Diagnosis Code T78.3

Angioneurotic edema

2016

2017

2018

2019

2020

2021

2022

Non-Billable/Non-Specific Code

T78.3 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
The 2022 edition of ICD-10-CM T78.3 became effective on October 1, 2021.
This is the American ICD-10-CM version of T78.3 - other international versions of ICD-10 T78.3 may differ.

Applicable To

Allergic angioedema
Giant urticaria
Quincke's edema

Type 1 Excludes

Type 1 Excludes Help

A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as T78.3. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

serum urticaria (
ICD-10-CM Diagnosis Code T80.6
Other serum reactions
Applicable To
- Intoxication by serum
- Protein sickness
- Serum rash
- Serum sickness
- Serum urticaria
Type 2 Excludes
- serum hepatitis (B16-B19)
T80.6-
)
urticaria (
ICD-10-CM Diagnosis Code L50
- L50 Urticaria
  - L50.0 Allergic urticaria
  - L50.1 Idiopathic urticaria
  - L50.2 Urticaria due to cold and heat
  - L50.3 Dermatographic urticaria
  - L50.4 Vibratory urticaria
  - L50.5 Cholinergic urticaria
  - L50.6 Contact urticaria
  - L50.8 Other urticaria
  - L50.9 Urticaria, unspecified
L50.-
)

The following code(s) above T78.3 contain annotation back-references

Annotation Back-References

In this context, annotation back-references refer to codes that contain:

Applicable To annotations, or
Code Also annotations, or
Code First annotations, or
Excludes1 annotations, or
Excludes2 annotations, or
Includes annotations, or
Note annotations, or
Use Additional annotations

that may be applicable to T78.3:

S00-T88
2022 ICD-10-CM Range S00-T88
Injury, poisoning and certain other consequences of external causes
Note
- Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
Type 1 Excludes
- birth trauma (P10-P15)
- obstetric trauma (O70-O71)
Use Additional
- code to identify any retained foreign body, if applicable (Z18.-)
Injury, poisoning and certain other consequences of external causes
T78
ICD-10-CM Diagnosis Code T78
Adverse effects, not elsewhere classified
Type 2 Excludes
- complications of surgical and medical care NEC (T80-T88)
Adverse effects, not elsewhere classified

Clinical Information

Recurring attacks of transient edema suddenly appearing in areas of the skin or mucous membranes
Swelling involving the deep dermis, subcutaneous, or submucosal tissues, representing localized edema. Angioedema often occurs in the face, lips, tongue, and larynx.

Code History

2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
2017 (effective 10/1/2016): No change
2018 (effective 10/1/2017): No change
2019 (effective 10/1/2018): No change
2020 (effective 10/1/2019): No change
2021 (effective 10/1/2020): No change
2022 (effective 10/1/2021): No change

Code annotations containing back-references to T78.3:

Type 1 Excludes: L50
, L50
, L50
, R60

ICD-10-CM Diagnosis Code L50
Urticaria
Type 1 Excludes
- allergic contact dermatitis (L23.-)
- angioneurotic edema (T78.3)
- giant urticaria (T78.3)
- hereditary angio-edema (D84.1)
- Quincke's edema (T78.3)
- serum urticaria (T80.6-)
- solar urticaria (L56.3)
- urticaria neonatorum (P83.8)
- urticaria papulosa (L28.2)
- urticaria pigmentosa (D47.01)
ICD-10-CM Diagnosis Code L50
Urticaria
Type 1 Excludes
- allergic contact dermatitis (L23.-)
- angioneurotic edema (T78.3)
- giant urticaria (T78.3)
- hereditary angio-edema (D84.1)
- Quincke's edema (T78.3)
- serum urticaria (T80.6-)
- solar urticaria (L56.3)
- urticaria neonatorum (P83.8)
- urticaria papulosa (L28.2)
- urticaria pigmentosa (D47.01)
ICD-10-CM Diagnosis Code L50
Urticaria
Type 1 Excludes
- allergic contact dermatitis (L23.-)
- angioneurotic edema (T78.3)
- giant urticaria (T78.3)
- hereditary angio-edema (D84.1)
- Quincke's edema (T78.3)
- serum urticaria (T80.6-)
- solar urticaria (L56.3)
- urticaria neonatorum (P83.8)
- urticaria papulosa (L28.2)
- urticaria pigmentosa (D47.01)
ICD-10-CM Diagnosis Code R60
Edema, not elsewhere classified
Type 1 Excludes
- angioneurotic edema (T78.3)
- ascites (R18.-)
- cerebral edema (G93.6)
- cerebral edema due to birth injury (P11.0)
- edema of larynx (J38.4)
- edema of nasopharynx (J39.2)
- edema of pharynx (J39.2)
- gestational edema (O12.0-)
- hereditary edema (Q82.0)
- hydrops fetalis NOS (P83.2)
- hydrothorax (J94.8)
- newborn edema (P83.3)
- pulmonary edema (J81.-)

Diagnosis Index entries containing back-references to T78.3:

Allergy, allergic (reaction) (to) T78.40
ICD-10-CM Diagnosis Code T78.40
Allergy, unspecified
Applicable To
Allergic reaction NOS
Hypersensitivity NOS
- angioneurotic edema T78.3
Angioedema (allergic) (any site) (with urticaria) T78.3
Angioneurotic edema (allergic) (any site) (with urticaria) T78.3
Bannister's disease T78.3
Disease, diseased - see also Syndrome
- Bannister's T78.3
Edema, edematous (infectious) (pitting) (toxic) R60.9
ICD-10-CM Diagnosis Code R60.9
Edema, unspecified
Applicable To
Fluid retention NOS
- angioneurotic (allergic) (any site) (with urticaria) T78.3
- circumscribed, acute T78.3
- essential, acute T78.3
- glottis, glottic, glottidis (obstructive) (passive) J38.4
  ICD-10-CM Diagnosis Code J38.4
  Edema of larynx
  2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
  Applicable To
  Edema (of) glottis
  Subglottic edema
  Supraglottic edema
  Type 1 Excludes
  acute obstructive laryngitis [croup] (J05.0)
  edematous laryngitis (J04.0)
  - allergic T78.3
- periodic T78.3
- Quincke's T78.3
- allergic T78.3
Giant
- urticaria T78.3
Quincke's disease or edema T78.3
Urticaria L50.9
ICD-10-CM Diagnosis Code L50.9
Urticaria, unspecified
- with angioneurotic edema T78.3
- giant T78.3
- larynx T78.3
- gigantea T78.3

ICD-10-CM Codes Adjacent To T78.3

T78.09XD …… subsequent encounter

T78.09XS …… sequela

T78.1 Other adverse food reactions, not elsewhere classified

T78.1XXA …… initial encounter

T78.1XXD …… subsequent encounter

T78.1XXS …… sequela

T78.2 Anaphylactic shock, unspecified

T78.2XXA …… initial encounter

T78.2XXD …… subsequent encounter

T78.2XXS …… sequela

T78.3 Angioneurotic edema

T78.3XXA …… initial encounter

T78.3XXD …… subsequent encounter

T78.3XXS …… sequela

T78.4 Other and unspecified allergy

T78.40 Allergy, unspecified

T78.40XA …… initial encounter

T78.40XD …… subsequent encounter

T78.40XS …… sequela

T78.41 Arthus phenomenon

T78.41XA …… initial encounter

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

2022 ICD-10-CM Diagnosis Code T78.3

Angioneurotic edema

Other serum reactions

Injury, poisoning and certain other consequences of external causes

Adverse effects, not elsewhere classified

Urticaria

Urticaria

Urticaria

Edema, not elsewhere classified

Allergy, unspecified

Edema, unspecified

Edema of larynx

Urticaria, unspecified