2022 ICD-10-CM Diagnosis Code T78.41

Arthus phenomenon

    2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
  • T78.41 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2022 edition of ICD-10-CM T78.41 became effective on October 1, 2021.
  • This is the American ICD-10-CM version of T78.41 - other international versions of ICD-10 T78.41 may differ.
Applicable To
  • Arthus reaction
The following code(s) above T78.41 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to T78.41:
  • S00-T88
    2022 ICD-10-CM Range S00-T88

    Injury, poisoning and certain other consequences of external causes

    • Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
    Type 1 Excludes
    Use Additional
    • code to identify any retained foreign body, if applicable (Z18.-)
    Injury, poisoning and certain other consequences of external causes
  • T78
    ICD-10-CM Diagnosis Code T78

    Adverse effects, not elsewhere classified

      2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
    Type 2 Excludes
    • complications of surgical and medical care NEC (T80-T88)
    Adverse effects, not elsewhere classified
  • T78.4
    ICD-10-CM Diagnosis Code T78.4

    Other and unspecified allergy

      2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • specified types of allergic reaction such as:
    • allergic diarrhea (K52.29)
    • allergic gastroenteritis and colitis (K52.29)
    • dermatitis (L23-L25, L27.-)
    • food protein-induced enterocolitis syndrome (K52.21)
    • food protein-induced enteropathy (K52.22)
    • hay fever (J30.1)
    Other and unspecified allergy
Clinical Information
  • A dermal inflammatory reaction produced under conditions of antibody excess, when a second injection of antigen produces intravascular antigen-antibody complexes which bind complement, causing cell clumping, endothelial damage, and vascular necrosis.
  • Development of an inflammatory lesion a few hours after intradermal injection of antigen into a sensitized animal; the lesion results from precipitation of immune complex, which causes complement activation and tissue destruction.
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change

Diagnosis Index entries containing back-references to T78.41:

ICD-10-CM Codes Adjacent To T78.41
T78.2XXS …… sequela
T78.3 Angioneurotic edema
T78.3XXA …… initial encounter
T78.3XXD …… subsequent encounter
T78.3XXS …… sequela
T78.4 Other and unspecified allergy
T78.40 Allergy, unspecified
T78.40XA …… initial encounter
T78.40XD …… subsequent encounter
T78.40XS …… sequela
T78.41 Arthus phenomenon
T78.41XA …… initial encounter
T78.41XD …… subsequent encounter
T78.41XS …… sequela
T78.49 Other allergy
T78.49XA …… initial encounter
T78.49XD …… subsequent encounter
T78.49XS …… sequela
T78.8 Other adverse effects, not elsewhere classified
T78.8XXA …… initial encounter
T78.8XXD …… subsequent encounter

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.