ICD-10-CM Codes
S00-T88
T80-T88
T80-
2023 ICD-10-CM Diagnosis Code T80.51

2023 ICD-10-CM Diagnosis Code T80.51

Anaphylactic reaction due to administration of blood and blood products

2016

2017

2018

2019

2020

2021

2022

2023

Non-Billable/Non-Specific Code

T80.51 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
Short description: Anaphylactic reaction due to admin blood/products
The 2023 edition of ICD-10-CM T80.51 became effective on October 1, 2022.
This is the American ICD-10-CM version of T80.51 - other international versions of ICD-10 T80.51 may differ.

The following code(s) above T80.51 contain annotation back-references

Annotation Back-References

In this context, annotation back-references refer to codes that contain:

Applicable To annotations, or
Code Also annotations, or
Code First annotations, or
Excludes1 annotations, or
Excludes2 annotations, or
Includes annotations, or
Note annotations, or
Use Additional annotations

that may be applicable to T80.51:

S00-T88
2023 ICD-10-CM Range S00-T88
Injury, poisoning and certain other consequences of external causes
Note
- Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
Type 1 Excludes
- birth trauma (P10-P15)
- obstetric trauma (O70-O71)
Use Additional
- code to identify any retained foreign body, if applicable (Z18.-)
Injury, poisoning and certain other consequences of external causes
T80-T88
2023 ICD-10-CM Range T80-T88
Complications of surgical and medical care, not elsewhere classified
Type 2 Excludes
- any encounters with medical care for postprocedural conditions in which no complications are present, such as:
- artificial opening status (Z93.-)
- closure of external stoma (Z43.-)
- fitting and adjustment of external prosthetic device (Z44.-)
- burns and corrosions from local applications and irradiation (T20-T32)
- complications of surgical procedures during pregnancy, childbirth and the puerperium (O00-O9A)
- mechanical complication of respirator [ventilator] (J95.850)
- poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
- postprocedural fever (R50.82)
- specified complications classified elsewhere, such as:
- cerebrospinal fluid leak from spinal puncture (G97.0)
- colostomy malfunction (K94.0-)
- disorders of fluid and electrolyte imbalance (E86-E87)
- functional disturbances following cardiac surgery (I97.0-I97.1)
- intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)
- ostomy complications (J95.0-, K94.-, N99.5-)
- postgastric surgery syndromes (K91.1)
- postlaminectomy syndrome NEC (M96.1)
- postmastectomy lymphedema syndrome (I97.2)
- postsurgical blind-loop syndrome (K91.2)
- ventilator associated pneumonia (J95.851)
Use Additional
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
Complications of surgical and medical care, not elsewhere classified
T80
ICD-10-CM Diagnosis Code T80
Complications following infusion, transfusion and therapeutic injection
Includes
- complications following perfusion
Type 2 Excludes
- bone marrow transplant rejection (T86.01)
- febrile nonhemolytic transfusion reaction (R50.84)
- fluid overload due to transfusion (E87.71)
- posttransfusion purpura (D69.51)
- transfusion associated circulatory overload (TACO) (E87.71)
- transfusion (red blood cell) associated hemochromatosis (E83.111)
- transfusion related acute lung injury (TRALI) (J95.84)
Complications following infusion, transfusion and therapeutic injection
T80.5
ICD-10-CM Diagnosis Code T80.5
Anaphylactic reaction due to serum
Applicable To
- Allergic shock due to serum
- Anaphylactic shock due to serum
- Anaphylactoid reaction due to serum
- Anaphylaxis due to serum
Type 1 Excludes
- ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-)
- allergic reaction or shock NOS (T78.2)
- anaphylactic reaction or shock NOS (T78.2)
- anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6)
- other serum reaction (T80.6-)
Anaphylactic reaction due to serum

Code History

2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
2017 (effective 10/1/2016): No change
2018 (effective 10/1/2017): No change
2019 (effective 10/1/2018): No change
2020 (effective 10/1/2019): No change
2021 (effective 10/1/2020): No change
2022 (effective 10/1/2021): No change
2023 (effective 10/1/2022): No change

Diagnosis Index entries containing back-references to T80.51:

Allergy, allergic (reaction) (to) T78.40
ICD-10-CM Diagnosis Code T78.40
Allergy, unspecified
Applicable To
Allergic reaction NOS
Hypersensitivity NOS
- shock (anaphylactic) T78.2
  ICD-10-CM Diagnosis Code T78.2
  Anaphylactic shock, unspecified
  2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
  Applicable To
  Allergic shock
  Anaphylactic reaction
  Anaphylaxis
  Type 1 Excludes
  anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6)
  anaphylactic reaction or shock due to adverse food reaction (T78.0-)
  anaphylactic reaction or shock due to serum (T80.5-)
  - due to
    - administration of blood and blood products T80.51
Shock R57.9
ICD-10-CM Diagnosis Code R57.9
Shock, unspecified
Applicable To
Failure of peripheral circulation NOS
- anaphylactic T78.2
  ICD-10-CM Diagnosis Code T78.2
  Anaphylactic shock, unspecified
  2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
  Applicable To
  Allergic shock
  Anaphylactic reaction
  Anaphylaxis
  Type 1 Excludes
  anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6)
  anaphylactic reaction or shock due to adverse food reaction (T78.0-)
  anaphylactic reaction or shock due to serum (T80.5-)
  - serum T80.59
    ICD-10-CM Diagnosis Code T80.59
    Anaphylactic reaction due to other serum
    2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    - blood and blood products T80.51

ICD-10-CM Codes Adjacent To T80.51

T80.A11S …… sequela

T80.A19 Non-ABO incompatibility with hemolytic transfusion reaction, unspecified

T80.A19A …… initial encounter

T80.A19D …… subsequent encounter

T80.A19S …… sequela

T80.A9 Other non-ABO incompatibility reaction due to transfusion of blood or blood products

T80.A9XA …… initial encounter

T80.A9XD …… subsequent encounter

T80.A9XS …… sequela

T80.5 Anaphylactic reaction due to serum

T80.51 Anaphylactic reaction due to administration of blood and blood products

T80.51XA …… initial encounter

T80.51XD …… subsequent encounter

T80.51XS …… sequela

T80.52 Anaphylactic reaction due to vaccination

T80.52XA …… initial encounter

T80.52XD …… subsequent encounter

T80.52XS …… sequela

T80.59 Anaphylactic reaction due to other serum

T80.59XA …… initial encounter

T80.59XD …… subsequent encounter

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

2023 ICD-10-CM Diagnosis Code T80.51

Anaphylactic reaction due to administration of blood and blood products

Injury, poisoning and certain other consequences of external causes

Complications of surgical and medical care, not elsewhere classified

Complications following infusion, transfusion and therapeutic injection

Anaphylactic reaction due to serum

Allergy, unspecified

Anaphylactic shock, unspecified

Shock, unspecified

Anaphylactic shock, unspecified

Anaphylactic reaction due to other serum