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ICD-10-CM Codes
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S00-T88
Injury, poisoning and certain other consequences of external causes
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T80-T88
Complications of surgical and medical care, not elsewhere classified
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T88-
Other complications of surgical and medical care, not elsewhere classified
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2022 ICD-10-CM Diagnosis Code T88.3
2022 ICD-10-CM Diagnosis Code T88.3
Malignant hyperthermia due to anesthesia
2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
- T88.3 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
- The 2022 edition of ICD-10-CM T88.3 became effective on October 1, 2021.
- This is the American ICD-10-CM version of T88.3 - other international versions of ICD-10 T88.3 may differ.
Use AdditionalUse Additional Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
The following code(s) above
T88.3 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
- Applicable To annotations, or
- Code Also annotations, or
- Code First annotations, or
- Excludes1 annotations, or
- Excludes2 annotations, or
- Includes annotations, or
- Note annotations, or
- Use Additional annotations
that may be applicable to
T88.3:
- S00-T88
2022 ICD-10-CM Range S00-T88
Injury, poisoning and certain other consequences of external causesNote- Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
Use Additional- code to identify any retained foreign body, if applicable (Z18.-)
- T80-T88
2022 ICD-10-CM Range T80-T88
Complications of surgical and medical care, not elsewhere classifiedType 2 Excludes- any encounters with medical care for postprocedural conditions in which no complications are present, such as:
- artificial opening status (Z93.-)
- closure of external stoma (Z43.-)
- fitting and adjustment of external prosthetic device (Z44.-)
- burns and corrosions from local applications and irradiation (T20-T32)
- complications of surgical procedures during pregnancy, childbirth and the puerperium (O00-O9A)
- mechanical complication of respirator [ventilator] (J95.850)
- poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
- postprocedural fever (R50.82)
- specified complications classified elsewhere, such as:
- cerebrospinal fluid leak from spinal puncture (G97.0)
- colostomy malfunction (K94.0-)
- disorders of fluid and electrolyte imbalance (E86-E87)
- functional disturbances following cardiac surgery (I97.0-I97.1)
- intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)
- ostomy complications (J95.0-, K94.-, N99.5-)
- postgastric surgery syndromes (K91.1)
- postlaminectomy syndrome NEC (M96.1)
- postmastectomy lymphedema syndrome (I97.2)
- postsurgical blind-loop syndrome (K91.2)
- ventilator associated pneumonia (J95.851)
Use Additional- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- T88
ICD-10-CM Diagnosis Code T88
Other complications of surgical and medical care, not elsewhere classified
2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
Type 2 Excludes- complication following infusion, transfusion and therapeutic injection (T80.-)
- complication following procedure NEC (T81.-)
- complications of anesthesia in labor and delivery (O74.-)
- complications of anesthesia in pregnancy (O29.-)
- complications of anesthesia in puerperium (O89.-)
- complications of devices, implants and grafts (T82-T85)
- complications of obstetric surgery and procedure (O75.4)
- dermatitis due to drugs and medicaments (L23.3, L24.4, L25.1, L27.0-L27.1)
- poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
- specified complications classified elsewhere
- A rare disorder characterized by rapid rise of the body temperature, accompanied by rhabdomyolysis and, if untreated, by collapse and death. It occurs in susceptible individuals who receive certain drugs for general anesthesia, gas anesthetics, or succinylcholine. It may be inherited in an autosomal dominant pattern.
- Rapid and excessive rise of temperature accompanied by muscular rigidity following general anesthesia.
- Usually inherited reaction to general anesthesia manifested as a sudden, rapid rise in temperature, hypermetabolism, and skeletal muscle rigidity; mutation is in the calcium release channel of skeletal muscle sarcoplasmic reticulum.
Code History
- 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
- 2017 (effective 10/1/2016): No change
- 2018 (effective 10/1/2017): No change
- 2019 (effective 10/1/2018): No change
- 2020 (effective 10/1/2019): No change
- 2021 (effective 10/1/2020): No change
- 2022 (effective 10/1/2021): No change
Code annotations containing back-references to T88.3:
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Type 1 Excludes: T67, R50
ICD-10-CM Diagnosis Code T67
Effects of heat and light
2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
Type 1 Excludes- erythema [dermatitis] ab igne (L59.0)
- malignant hyperpyrexia due to anesthesia (T88.3)
- radiation-related disorders of the skin and subcutaneous tissue (L55-L59)
ICD-10-CM Diagnosis Code R50
Fever of other and unknown origin
2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
Type 1 Excludes- chills without fever (R68.83)
- febrile convulsions (R56.0-)
- fever of unknown origin during labor (O75.2)
- fever of unknown origin in newborn (P81.9)
- hypothermia due to illness (R68.0)
- malignant hyperthermia due to anesthesia (T88.3)
- puerperal pyrexia NOS (O86.4)
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Type 2 Excludes: T81.8
ICD-10-CM Diagnosis Code T81.8
Other complications of procedures, not elsewhere classified
2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
Type 2 Excludes- hypothermia following anesthesia (T88.51)
- malignant hyperpyrexia due to anesthesia (T88.3)
- Complication(s) (from) (of)
- Hyperpyrexia R50.9
ICD-10-CM Diagnosis Code R50.9
Fever, unspecified
2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
Applicable To- Fever NOS
- Fever of unknown origin [FUO]
- Fever with chills
- Fever with rigors
- Hyperpyrexia NOS
- Persistent fever
- Pyrexia NOS
- malignant, due to anesthetic T88.3
- Hyperthermia (of unknown origin) - see also Hyperpyrexia
- malignant, due to anesthesia T88.3
ICD-10-CM Codes Adjacent To T88.3
T88.1 Other complications following immunization, not elsewhere classified
T88.2 Shock due to anesthesia
T88.3
Malignant hyperthermia due to anesthesia
T88.4 Failed or difficult intubation
T88.5 Other complications of anesthesia
T88.51 Hypothermia following anesthesia
Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.
