2020 ICD-10-CM Diagnosis Code Z15

Genetic susceptibility to disease

    2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
  • Z15 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2020 edition of ICD-10-CM Z15 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of Z15 - other international versions of ICD-10 Z15 may differ.
Use Additional
Use Additional Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • code, if applicable, for any associated family history of the disease (
    ICD-10-CM Diagnosis Code Z80

    Family history of primary malignant neoplasm

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Z80
    -
    ICD-10-CM Diagnosis Code Z84

    Family history of other conditions

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Z84
    )
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as Z15. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • chromosomal anomalies (Q90-Q99
    ICD-10-CM Range Q90-Q99

    Chromosomal abnormalities, not elsewhere classified

    Type 2 Excludes
    • mitochondrial metabolic disorders (E88.4-)
    • Q90 Down syndrome
    • Q91 Trisomy 18 and Trisomy 13
    • Q92 Other trisomies and partial trisomies of...
    • Q93 Monosomies and deletions from the autoso...
    • Q95 Balanced rearrangements and structural m...
    • Q96 Turner's syndrome
    • Q97 Other sex chromosome abnormalities, fema...
    • Q98 Other sex chromosome abnormalities, male...
    • Q99 Other chromosome abnormalities, not else...
    )
Includes
Includes Help
"Includes" further defines, or give examples of, the content of the code or category.
  • confirmed abnormal gene
The following code(s) above Z15 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to Z15:
  • Z00-Z99
    2020 ICD-10-CM Range Z00-Z99

    Factors influencing health status and contact with health services

    Note
    • Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
    • (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
    • (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.
    Factors influencing health status and contact with health services
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
ICD-10-CM Codes Adjacent To Z15
Z13.858 Encounter for screening for other nervous system disorders
Z13.88 Encounter for screening for disorder due to exposure to contaminants
Z13.89 Encounter for screening for other disorder
Z13.9 Encounter for screening, unspecified
Z14 Genetic carrier
Z14.0 Hemophilia A carrier
Z14.01 Asymptomatic hemophilia A carrier
Z14.02 Symptomatic hemophilia A carrier
Z14.1 Cystic fibrosis carrier
Z14.8 Genetic carrier of other disease
Z15 Genetic susceptibility to disease
Z15.0 Genetic susceptibility to malignant neoplasm
Z15.01 …… of breast
Z15.02 …… of ovary
Z15.03 …… of prostate
Z15.04 …… of endometrium
Z15.09 Genetic susceptibility to other malignant neoplasm
Z15.8 Genetic susceptibility to other disease
Z15.81 Genetic susceptibility to multiple endocrine neoplasia [MEN]
Z15.89 Genetic susceptibility to other disease
Z16 Resistance to antimicrobial drugs

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.