2021

  1. ICD-10-CM Codes
    2. ›
  2. Z00-Z99 Factors influencing health status and contact with health services
    3. ›
  3. Z14-Z15 Genetic carrier and genetic susceptibility to disease
    4. ›
  4. Z15- Genetic susceptibility to disease
    5. ›
  5. 2021 ICD-10-CM Diagnosis Code Z15.81

2021 ICD-10-CM Diagnosis Code Z15.81

Genetic susceptibility to multiple endocrine neoplasia [MEN]

    2016 2017 2018 2019 2020 2021 Billable/Specific Code POA Exempt
  • Z15.81 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2021 edition of ICD-10-CM Z15.81 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of Z15.81 - other international versions of ICD-10 Z15.81 may differ.
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as Z15.81. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • multiple endocrine neoplasia [MEN] syndromes (
    ICD-10-CM Diagnosis Code E31.2

    Multiple endocrine neoplasia [MEN] syndromes

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Applicable To
    • Multiple endocrine adenomatosis
    Code Also
    • any associated malignancies and other conditions associated with the syndromes
    E31.2-
    )
The following code(s) above Z15.81 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to Z15.81:
  • Z00-Z99
    2021 ICD-10-CM Range Z00-Z99

    Factors influencing health status and contact with health services

    Note
    • Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
    • (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
    • (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.
    Factors influencing health status and contact with health services
  • Z15
    ICD-10-CM Diagnosis Code Z15

    Genetic susceptibility to disease

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Includes
    • confirmed abnormal gene
    Type 1 Excludes
    Use Additional
    • code, if applicable, for any associated family history of the disease (Z80-Z84)
    Genetic susceptibility to disease
Approximate Synonyms
  • Genetic susceptibility to multiple endocrine neoplasia
Present On Admission
POA Help
"Present On Admission" is defined as present at the time the order for inpatient admission occurs — conditions that develop during an outpatient encounter, including emergency department, observation, or outpatient surgery, are considered POA.
  • Z15.81 is considered exempt from POA reporting.
ICD-10-CM Z15.81 is grouped within Diagnostic Related Group(s) (MS-DRG v38.0):
  • 951 Other factors influencing health status

Convert Z15.81 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change

Diagnosis Index entries containing back-references to Z15.81:
  • Genetic
    • susceptibility to disease NEC Z15.89
      ICD-10-CM Diagnosis Code Z15.89

      Genetic susceptibility to other disease

        2016 2017 2018 2019 2020 2021 Billable/Specific Code POA Exempt
      • multiple endocrine neoplasia Z15.81
  • Susceptibility to disease, genetic Z15.89
    ICD-10-CM Diagnosis Code Z15.89

    Genetic susceptibility to other disease

      2016 2017 2018 2019 2020 2021 Billable/Specific Code POA Exempt
    • multiple endocrine neoplasia Z15.81

ICD-10-CM Codes Adjacent To Z15.81
Z14.1 Cystic fibrosis carrier
Z14.8 Genetic carrier of other disease
Z15 Genetic susceptibility to disease
Z15.0 Genetic susceptibility to malignant neoplasm
Z15.01 …… of breast
Z15.02 …… of ovary
Z15.03 …… of prostate
Z15.04 …… of endometrium
Z15.09 Genetic susceptibility to other malignant neoplasm
Z15.8 Genetic susceptibility to other disease
Z15.81 Genetic susceptibility to multiple endocrine neoplasia [MEN]
Z15.89 Genetic susceptibility to other disease
Z16 Resistance to antimicrobial drugs
Z16.1 Resistance to beta lactam antibiotics
Z16.10 Resistance to unspecified beta lactam antibiotics
Z16.11 Resistance to penicillins
Z16.12 Extended spectrum beta lactamase (ESBL) resistance
Z16.19 Resistance to other specified beta lactam antibiotics
Z16.2 Resistance to other antibiotics
Z16.20 Resistance to unspecified antibiotic
Z16.21 Resistance to vancomycin

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

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