2023 ICD-10-CM Diagnosis Code Z79.818

Long term (current) use of other agents affecting estrogen receptors and estrogen levels

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code POA Exempt
  • Z79.818 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • Short description: Lng trm (crnt) use of agnt aff estrog recpt & estrog levels
  • The 2023 edition of ICD-10-CM Z79.818 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of Z79.818 - other international versions of ICD-10 Z79.818 may differ.
Applicable To
  • Long term (current) use of estrogen receptor downregulators
  • Long term (current) use of fulvestrant (Faslodex)
  • Long term (current) use of gonadotropin-releasing hormone (GnRH) agonist
  • Long term (current) use of goserelin acetate (Zoladex)
  • Long term (current) use of leuprolide acetate (leuprorelin) (Lupron)
  • Long term (current) use of megestrol acetate (Megace)
The following code(s) above Z79.818 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to Z79.818:
  • Z00-Z99
    2023 ICD-10-CM Range Z00-Z99

    Factors influencing health status and contact with health services

    Note
    • Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
    • (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
    • (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.
    Factors influencing health status and contact with health services
  • Z77-Z99
    2023 ICD-10-CM Range Z77-Z99

    Persons with potential health hazards related to family and personal history and certain conditions influencing health status

    Code Also
    • any follow-up examination (Z08-Z09)
    Persons with potential health hazards related to family and personal history and certain conditions influencing health status
  • Z79
    ICD-10-CM Diagnosis Code Z79

    Long term (current) drug therapy

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Code Also
    • any therapeutic drug level monitoring (Z51.81)
    Includes
    • long term (current) drug use for prophylactic purposes
    Type 2 Excludes
    • drug abuse and dependence (F11-F19)
    • drug use complicating pregnancy, childbirth, and the puerperium (O99.32-)
    Long term (current) drug therapy
  • Z79.81
    ICD-10-CM Diagnosis Code Z79.81

    Long term (current) use of agents affecting estrogen receptors and estrogen levels

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Code First
    • , if applicable:
    • malignant neoplasm of breast (C50.-)
    • malignant neoplasm of prostate (C61)
    Type 1 Excludes
    • hormone replacement therapy (Z79.890)
    Use Additional
    • code, if applicable, to identify:
    • estrogen receptor positive status (Z17.0)
    • family history of breast cancer (Z80.3)
    • genetic susceptibility to malignant neoplasm (cancer) (Z15.0-)
    • personal history of breast cancer (Z85.3)
    • personal history of prostate cancer (Z85.46)
    • postmenopausal status (Z78.0)
    Long term (current) use of agents affecting estrogen receptors and estrogen levels
Approximate Synonyms
  • Long term current use of leuprorelin (lupron) dosed by calendar
  • Long term current use of leuprorelin (lupron) dosed by psa level
  • Long term current use of leuprorelin (lupron) dosed by testosterone level
  • Long term leuprolide therapy
  • Long-term current use of leuprolide
  • Long-term current use of leuprolide, dosed by calendar
  • Long-term current use of leuprolide, dosed by prostate specific antigen level
  • Long-term current use of leuprolide, dosed by testosterone level
Present On Admission
POA Help
"Present On Admission" is defined as present at the time the order for inpatient admission occurs — conditions that develop during an outpatient encounter, including emergency department, observation, or outpatient surgery, are considered POA.
  • Z79.818 is considered exempt from POA reporting.
ICD-10-CM Z79.818 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 951 Other factors influencing health status

Convert Z79.818 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change

Diagnosis Index entries containing back-references to Z79.818:
  • Long-term (current) (prophylactic) drug therapy (use of)
    • agents affecting estrogen receptors and estrogen levels NEC Z79.818
    • estrogen receptor downregulators Z79.818
    • fulvestrant Z79.818 (Faslodex)
    • gonadotropin-releasing hormone Z79.818 (GnRH)
    • goserelin acetate Z79.818 (Zoladex)
    • leuprolide acetate Z79.818 (leuprorelin) (Lupron)
    • megestrol acetate Z79.818 (Megace)
  • Therapy
    • drug, long-term (current) (prophylactic)
      • agents affecting estrogen receptors and estrogen levels NEC Z79.818
      • estrogen receptor downregulators Z79.818
      • fulvestrant Z79.818 (Faslodex)
      • gonadotropin-releasing hormone Z79.818 (GnRH)
      • goserelin acetate Z79.818 (Zoladex)
      • leuprolide acetate Z79.818 (leuprorelin) (Lupron)
      • megestrol acetate Z79.818 (Megace)

ICD-10-CM Codes Adjacent To Z79.818
Z79.631 Long term (current) use of antimetabolite agent
Z79.632 Long term (current) use of antitumor antibiotic
Z79.633 Long term (current) use of mitotic inhibitor
Z79.634 Long term (current) use of topoisomerase inhibitor
Z79.64 Long term (current) use of myelosuppressive agent
Z79.69 Long term (current) use of other immunomodulators and immunosuppressants
Z79.8 Other long term (current) drug therapy
Z79.81 Long term (current) use of agents affecting estrogen receptors and estrogen levels
Z79.810 Long term (current) use of selective estrogen receptor modulators (SERMs)
Z79.811 Long term (current) use of aromatase inhibitors
Z79.818 Long term (current) use of other agents affecting estrogen receptors and estrogen levels
Z79.82 Long term (current) use of aspirin
Z79.83 Long term (current) use of bisphosphonates
Z79.84 Long term (current) use of oral hypoglycemic drugs
Z79.85 Long-term (current) use of injectable non-insulin antidiabetic drugs
Z79.89 Other long term (current) drug therapy
Z79.890 Hormone replacement therapy
Z79.891 Long term (current) use of opiate analgesic
Z79.899 Other long term (current) drug therapy
Z80 Family history of primary malignant neoplasm
Z80.0 Family history of malignant neoplasm of digestive organs

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.