DRG 808

Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders with mcc

  • D59.0
    Drug-induced autoimmune hemolytic anemia
  • D59.10
    Autoimmune hemolytic anemia, unspecified
  • D59.11
    Warm autoimmune hemolytic anemia
  • D59.12
    Cold autoimmune hemolytic anemia
  • D59.13
    Mixed type autoimmune hemolytic anemia
  • D59.19
    Other autoimmune hemolytic anemia
  • D59.2
    Drug-induced nonautoimmune hemolytic anemia
  • D59.4
    Other nonautoimmune hemolytic anemias
  • D59.5
    Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]
  • D59.6
    Hemoglobinuria due to hemolysis from other external causes
  • D59.8
    Other acquired hemolytic anemias
  • D59.9
    Acquired hemolytic anemia, unspecified
  • D60.0
    Chronic acquired pure red cell aplasia
  • D60.1
    Transient acquired pure red cell aplasia
  • D60.8
    Other acquired pure red cell aplasias
  • D60.9
    Acquired pure red cell aplasia, unspecified
  • D61.01
    Constitutional (pure) red blood cell aplasia
  • D61.09
    Other constitutional aplastic anemia
  • D61.1
    Drug-induced aplastic anemia
  • D61.2
    Aplastic anemia due to other external agents
  • D61.3
    Idiopathic aplastic anemia
  • D61.810
    Antineoplastic chemotherapy induced pancytopenia
  • D61.811
    Other drug-induced pancytopenia
  • D61.818
    Other pancytopenia
  • D61.89
    Other specified aplastic anemias and other bone marrow failure syndromes
  • D61.9
    Aplastic anemia, unspecified
  • D70.0
    Congenital agranulocytosis
  • D70.1
    Agranulocytosis secondary to cancer chemotherapy
  • D70.2
    Other drug-induced agranulocytosis
  • D70.3
    Neutropenia due to infection
  • D70.4
    Cyclic neutropenia
  • D70.8
    Other neutropenia
  • D70.9
    Neutropenia, unspecified
  • D71
    Functional disorders of polymorphonuclear neutrophils
  • D72.0
    Genetic anomalies of leukocytes
  • D80.6
    Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia
  • D80.8
    Other immunodeficiencies with predominantly antibody defects
  • D80.9
    Immunodeficiency with predominantly antibody defects, unspecified
  • D81.0
    Severe combined immunodeficiency [SCID] with reticular dysgenesis
  • D81.1
    Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
  • D81.2
    Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
  • D81.4
    Nezelof's syndrome
  • D81.6
    Major histocompatibility complex class I deficiency
  • D81.7
    Major histocompatibility complex class II deficiency
  • D81.82
    Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]
  • D81.89
    Other combined immunodeficiencies
  • D81.9
    Combined immunodeficiency, unspecified
  • D82.0
    Wiskott-Aldrich syndrome
  • D82.1
    Di George's syndrome
  • D89.810
    Acute graft-versus-host disease
  • D89.811
    Chronic graft-versus-host disease
  • D89.812
    Acute on chronic graft-versus-host disease
  • D89.813
    Graft-versus-host disease, unspecified
  • T86.00
    Unspecified complication of bone marrow transplant
  • T86.01
    Bone marrow transplant rejection
  • T86.02
    Bone marrow transplant failure
  • T86.03
    Bone marrow transplant infection
  • T86.09
    Other complications of bone marrow transplant
ICD-10-CM D59.0

Drug-induced autoimmune hemolytic anemia

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Use Additional
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
ICD-10-CM D59.10

Autoimmune hemolytic anemia, unspecified

    2021 - New Code 2022 2023 Billable/Specific Code
ICD-10-CM D59.11

Warm autoimmune hemolytic anemia

    2021 - New Code 2022 2023 Billable/Specific Code
Applicable To
  • Warm type (primary) (secondary) (symptomatic) autoimmune hemolytic anemia
  • Warm type autoimmune hemolytic disease
ICD-10-CM D59.12

Cold autoimmune hemolytic anemia

    2021 - New Code 2022 2023 Billable/Specific Code
Applicable To
  • Chronic cold hemagglutinin disease
  • Cold agglutinin disease
  • Cold agglutinin hemoglobinuria
  • Cold type (primary) (secondary) (symptomatic) autoimmune hemolytic anemia
  • Cold type autoimmune hemolytic disease
ICD-10-CM D59.13

Mixed type autoimmune hemolytic anemia

    2021 - New Code 2022 2023 Billable/Specific Code
Applicable To
  • Mixed type autoimmune hemolytic disease
  • Mixed type, cold and warm, (primary) (secondary) (symptomatic) autoimmune hemolytic anemia
ICD-10-CM D59.19

Other autoimmune hemolytic anemia

    2021 - New Code 2022 2023 Billable/Specific Code
ICD-10-CM D59.2

Drug-induced nonautoimmune hemolytic anemia

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To
  • Drug-induced enzyme deficiency anemia
Use Additional
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
ICD-10-CM D59.4

Other nonautoimmune hemolytic anemias

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To
  • Mechanical hemolytic anemia
  • Microangiopathic hemolytic anemia
  • Toxic hemolytic anemia
ICD-10-CM D59.5

Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Type 1 Excludes
  • hemoglobinuria NOS (R82.3)
ICD-10-CM D59.6

Hemoglobinuria due to hemolysis from other external causes

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To
  • Hemoglobinuria from exertion
  • March hemoglobinuria
  • Paroxysmal cold hemoglobinuria
Type 1 Excludes
  • hemoglobinuria NOS (R82.3)
Use Additional
  • code (Chapter 20) to identify external cause
ICD-10-CM D59.8

Other acquired hemolytic anemias

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D59.9

Acquired hemolytic anemia, unspecified

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To
  • Idiopathic hemolytic anemia, chronic
ICD-10-CM D60.0

Chronic acquired pure red cell aplasia

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D60.1

Transient acquired pure red cell aplasia

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D60.8

Other acquired pure red cell aplasias

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D60.9

Acquired pure red cell aplasia, unspecified

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D61.01

Constitutional (pure) red blood cell aplasia

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To
  • Blackfan-Diamond syndrome
  • Congenital (pure) red cell aplasia
  • Familial hypoplastic anemia
  • Primary (pure) red cell aplasia
  • Red cell (pure) aplasia of infants
Type 1 Excludes
  • acquired red cell aplasia (D60.9)
ICD-10-CM D61.09

Other constitutional aplastic anemia

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To
  • Fanconi's anemia
  • Pancytopenia with malformations
ICD-10-CM D61.1

Drug-induced aplastic anemia

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Use Additional
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
ICD-10-CM D61.2

Aplastic anemia due to other external agents

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Code First
  • , if applicable, toxic effects of substances chiefly nonmedicinal as to source (T51-T65)
ICD-10-CM D61.3

Idiopathic aplastic anemia

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D61.810

Antineoplastic chemotherapy induced pancytopenia

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Type 2 Excludes
  • aplastic anemia due to antineoplastic chemotherapy (D61.1)
ICD-10-CM D61.811

Other drug-induced pancytopenia

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Type 2 Excludes
  • aplastic anemia due to drugs (D61.1)
ICD-10-CM D61.818

Other pancytopenia

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D61.89

Other specified aplastic anemias and other bone marrow failure syndromes

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D61.9

Aplastic anemia, unspecified

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To
  • Hypoplastic anemia NOS
  • Medullary hypoplasia
ICD-10-CM D70.0

Congenital agranulocytosis

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To
  • Congenital neutropenia
  • Infantile genetic agranulocytosis
  • Kostmann's disease
ICD-10-CM D70.1

Agranulocytosis secondary to cancer chemotherapy

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Code Also
  • underlying neoplasm
Use Additional
  • code for adverse effect, if applicable, to identify drug (T45.1X5)
ICD-10-CM D70.2

Other drug-induced agranulocytosis

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Use Additional
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
ICD-10-CM D70.3

Neutropenia due to infection

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D70.4

Cyclic neutropenia

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To
  • Cyclic hematopoiesis
  • Periodic neutropenia
ICD-10-CM D70.8

Other neutropenia

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D70.9

Neutropenia, unspecified

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D71

Functional disorders of polymorphonuclear neutrophils

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To
  • Cell membrane receptor complex [CR3] defect
  • Chronic (childhood) granulomatous disease
  • Congenital dysphagocytosis
  • Progressive septic granulomatosis
ICD-10-CM D72.0

Genetic anomalies of leukocytes

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To
  • Alder (granulation) (granulocyte) anomaly
  • Alder syndrome
  • Hereditary leukocytic hypersegmentation
  • Hereditary leukocytic hyposegmentation
  • Hereditary leukomelanopathy
  • May-Hegglin (granulation) (granulocyte) anomaly
  • May-Hegglin syndrome
  • Pelger-Huët (granulation) (granulocyte) anomaly
  • Pelger-Huët syndrome
Type 1 Excludes
  • Chédiak (-Steinbrinck)-Higashi syndrome (E70.330)
ICD-10-CM D80.6

Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D80.8

Other immunodeficiencies with predominantly antibody defects

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To
  • Kappa light chain deficiency
ICD-10-CM D80.9

Immunodeficiency with predominantly antibody defects, unspecified

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D81.0

Severe combined immunodeficiency [SCID] with reticular dysgenesis

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D81.1

Severe combined immunodeficiency [SCID] with low T- and B-cell numbers

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D81.2

Severe combined immunodeficiency [SCID] with low or normal B-cell numbers

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D81.4

Nezelof's syndrome

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D81.6

Major histocompatibility complex class I deficiency

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To
  • Bare lymphocyte syndrome
ICD-10-CM D81.7

Major histocompatibility complex class II deficiency

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D81.82

Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]

    2023 - New Code Billable/Specific Code
Applicable To
  • p110d-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency [PASLI] disease
Code Also
  • , if applicable, any associated manifestations, such as:
  • bronchiectasis (J47.-)
  • herpes virus infections (B00.-)
  • other acute respiratory tract infections (J00-J06; J20-J22)
  • other infections (A00-B99)
  • pneumonia (J12-J18)
ICD-10-CM D81.89

Other combined immunodeficiencies

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D81.9

Combined immunodeficiency, unspecified

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To
  • Severe combined immunodeficiency disorder [SCID] NOS
ICD-10-CM D82.0

Wiskott-Aldrich syndrome

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To
  • Immunodeficiency with thrombocytopenia and eczema
ICD-10-CM D82.1

Di George's syndrome

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To
  • Pharyngeal pouch syndrome
  • Thymic alymphoplasia
  • Thymic aplasia or hypoplasia with immunodeficiency
ICD-10-CM D89.810

Acute graft-versus-host disease

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D89.811

Chronic graft-versus-host disease

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D89.812

Acute on chronic graft-versus-host disease

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM D89.813

Graft-versus-host disease, unspecified

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM T86.00

Unspecified complication of bone marrow transplant

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM T86.01

Bone marrow transplant rejection

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM T86.02

Bone marrow transplant failure

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM T86.03

Bone marrow transplant infection

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM T86.09

Other complications of bone marrow transplant

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code