Resistance, resistant (to)

• activated protein C D68.51
  ICD-10-CM Diagnosis Code D68.51

  Activated protein C resistance

  2016 2017 2018 2019 2020 Billable/Specific Code

  Applicable To

  • Factor V Leiden mutation
• complicating pregnancy O26.89
  ICD-10-CM Diagnosis Code O26.89

  Other specified pregnancy related conditions

  2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
• insulin E88.81
  ICD-10-CM Diagnosis Code E88.81

  Metabolic syndrome

  2016 2017 2018 2019 2020 Billable/Specific Code

  Applicable To

  • Dysmetabolic syndrome X

  Use Additional

  • codes for associated manifestations, such as:
  • obesity (E66.-)
• organism(s)
  • to
    • drug Z16.30
      ICD-10-CM Diagnosis Code Z16.30

      Resistance to unspecified antimicrobial drugs

      2016 2017 2018 2019 2020 Billable/Specific Code

      Applicable To

      • Drug resistance NOS
      • aminoglycosides Z16.29
        ICD-10-CM Diagnosis Code Z16.29

        Resistance to other single specified antibiotic

        2016 2017 2018 2019 2020 Billable/Specific Code

        Applicable To

        • Resistance to aminoglycosides
        • Resistance to macrolides
        • Resistance to sulfonamides
        • Resistance to tetracyclines
      • amoxicillin Z16.11
        ICD-10-CM Diagnosis Code Z16.11

        Resistance to penicillins

        2016 2017 2018 2019 2020 Billable/Specific Code

        Applicable To

        • Resistance to amoxicillin
        • Resistance to ampicillin
      • ampicillin Z16.11
        ICD-10-CM Diagnosis Code Z16.11

        Resistance to penicillins

        2016 2017 2018 2019 2020 Billable/Specific Code

        Applicable To

        • Resistance to amoxicillin
        • Resistance to ampicillin
      • antibiotic(s) Z16.20
        ICD-10-CM Diagnosis Code Z16.20

        Resistance to unspecified antibiotic

        2016 2017 2018 2019 2020 Billable/Specific Code

        Applicable To

        • Resistance to antibiotics NOS
        • multiple Z16.24
          ICD-10-CM Diagnosis Code Z16.24

          Resistance to multiple antibiotics

          2016 2017 2018 2019 2020 Billable/Specific Code
        • specified NEC Z16.29
          ICD-10-CM Diagnosis Code Z16.29

          Resistance to other single specified antibiotic

          2016 2017 2018 2019 2020 Billable/Specific Code

          Applicable To

          • Resistance to aminoglycosides
          • Resistance to macrolides
          • Resistance to sulfonamides
          • Resistance to tetracyclines
      • antifungal Z16.32
        ICD-10-CM Diagnosis Code Z16.32

        Resistance to antifungal drug(s)

        2016 2017 2018 2019 2020 Billable/Specific Code
      • antimicrobial (single) Z16.30
        ICD-10-CM Diagnosis Code Z16.30

        Resistance to unspecified antimicrobial drugs

        2016 2017 2018 2019 2020 Billable/Specific Code

        Applicable To

        • Drug resistance NOS
        • multiple Z16.35
          ICD-10-CM Diagnosis Code Z16.35

          Resistance to multiple antimicrobial drugs

          2016 2017 2018 2019 2020 Billable/Specific Code

          Type 1 Excludes

          • Resistance to multiple antibiotics only (Z16.24)
        • specified NEC Z16.39
          ICD-10-CM Diagnosis Code Z16.39

          Resistance to other specified antimicrobial drug

          2016 2017 2018 2019 2020 Billable/Specific Code
      • antimycobacterial (single) Z16.341
        ICD-10-CM Diagnosis Code Z16.341

        Resistance to single antimycobacterial drug

        2016 2017 2018 2019 2020 Billable/Specific Code

        Applicable To

        • Resistance to antimycobacterial drug NOS
        • multiple Z16.342
          ICD-10-CM Diagnosis Code Z16.342

          Resistance to multiple antimycobacterial drugs

          2016 2017 2018 2019 2020 Billable/Specific Code
      • antiparasitic Z16.31
        ICD-10-CM Diagnosis Code Z16.31

        Resistance to antiparasitic drug(s)

        2016 2017 2018 2019 2020 Billable/Specific Code

        Applicable To

        • Resistance to quinine and related compounds
      • antiviral Z16.33
        ICD-10-CM Diagnosis Code Z16.33

        Resistance to antiviral drug(s)

        2016 2017 2018 2019 2020 Billable/Specific Code
      • beta lactam antibiotics Z16.10
        ICD-10-CM Diagnosis Code Z16.10

        Resistance to unspecified beta lactam antibiotics

        2016 2017 2018 2019 2020 Billable/Specific Code
        • specified NEC Z16.19
          ICD-10-CM Diagnosis Code Z16.19

          Resistance to other specified beta lactam antibiotics

          2016 2017 2018 2019 2020 Billable/Specific Code

          Applicable To

          • Resistance to cephalosporins
      • cephalosporins Z16.19
        ICD-10-CM Diagnosis Code Z16.19

        Resistance to other specified beta lactam antibiotics

        2016 2017 2018 2019 2020 Billable/Specific Code

        Applicable To

        • Resistance to cephalosporins
      • extended beta lactamase Z16.12
        (ESBL)
        ICD-10-CM Diagnosis Code Z16.12

        Extended spectrum beta lactamase (ESBL) resistance

        2016 2017 2018 2019 2020 Billable/Specific Code

        Type 2 Excludes

        • Methicillin resistant Staphylococcus aureus infection in diseases classified elsewhere (B95.62)
      • fluoroquinolones Z16.23
        ICD-10-CM Diagnosis Code Z16.23

        Resistance to quinolones and fluoroquinolones

        2016 2017 2018 2019 2020 Billable/Specific Code
      • macrolides Z16.29
        ICD-10-CM Diagnosis Code Z16.29

        Resistance to other single specified antibiotic

        2016 2017 2018 2019 2020 Billable/Specific Code

        Applicable To

        • Resistance to aminoglycosides
        • Resistance to macrolides
        • Resistance to sulfonamides
        • Resistance to tetracyclines
      • methicillin - see MRSA
      • multiple drugs (MDRO)
        • antibiotics Z16.24
          ICD-10-CM Diagnosis Code Z16.24

          Resistance to multiple antibiotics

          2016 2017 2018 2019 2020 Billable/Specific Code
        • antimicrobial Z16.35
          ICD-10-CM Diagnosis Code Z16.35

          Resistance to multiple antimicrobial drugs

          2016 2017 2018 2019 2020 Billable/Specific Code

          Type 1 Excludes

          • Resistance to multiple antibiotics only (Z16.24)
        • antimycobacterials Z16.342
          ICD-10-CM Diagnosis Code Z16.342

          Resistance to multiple antimycobacterial drugs

          2016 2017 2018 2019 2020 Billable/Specific Code
      • penicillins Z16.11
        ICD-10-CM Diagnosis Code Z16.11

        Resistance to penicillins

        2016 2017 2018 2019 2020 Billable/Specific Code

        Applicable To

        • Resistance to amoxicillin
        • Resistance to ampicillin
      • quinine Z16.31
        (and related compounds)
        ICD-10-CM Diagnosis Code Z16.31

        Resistance to antiparasitic drug(s)

        2016 2017 2018 2019 2020 Billable/Specific Code

        Applicable To

        • Resistance to quinine and related compounds
      • quinolones Z16.23
        ICD-10-CM Diagnosis Code Z16.23

        Resistance to quinolones and fluoroquinolones

        2016 2017 2018 2019 2020 Billable/Specific Code
      • sulfonamides Z16.29
        ICD-10-CM Diagnosis Code Z16.29

        Resistance to other single specified antibiotic

        2016 2017 2018 2019 2020 Billable/Specific Code

        Applicable To

        • Resistance to aminoglycosides
        • Resistance to macrolides
        • Resistance to sulfonamides
        • Resistance to tetracyclines
      • tetracyclines Z16.29
        ICD-10-CM Diagnosis Code Z16.29

        Resistance to other single specified antibiotic

        2016 2017 2018 2019 2020 Billable/Specific Code

        Applicable To

        • Resistance to aminoglycosides
        • Resistance to macrolides
        • Resistance to sulfonamides
        • Resistance to tetracyclines
      • tuberculostatics (single) Z16.341
        ICD-10-CM Diagnosis Code Z16.341

        Resistance to single antimycobacterial drug

        2016 2017 2018 2019 2020 Billable/Specific Code

        Applicable To

        • Resistance to antimycobacterial drug NOS
        • multiple Z16.342
          ICD-10-CM Diagnosis Code Z16.342

          Resistance to multiple antimycobacterial drugs

          2016 2017 2018 2019 2020 Billable/Specific Code
      • vancomycin Z16.21
        ICD-10-CM Diagnosis Code Z16.21

        Resistance to vancomycin

        2016 2017 2018 2019 2020 Billable/Specific Code
        • related antibiotics Z16.22
          ICD-10-CM Diagnosis Code Z16.22

          Resistance to vancomycin related antibiotics

          2016 2017 2018 2019 2020 Billable/Specific Code
• thyroid hormone E07.89
  ICD-10-CM Diagnosis Code E07.89

  Other specified disorders of thyroid

  2016 2017 2018 2019 2020 Billable/Specific Code

  Applicable To

  • Abnormality of thyroid-binding globulin
  • Hemorrhage of thyroid
  • Infarction of thyroid